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Recent studies show that the binding of HCV enveloped E2 protein to CD81 molecule leads to the lymphocyte functional disorders, which may play an important role in HCV chronic infection and have closed relation with B cell lymphadenoma and cryoglobulinemia. Associated with formation of HCV infection is hard to induce neutralizing antibody and thus leading to chronic infection.

最近的一些研究发现,HCV包膜E2蛋白与CD81分子结合所致免疫细胞的功能紊乱也可能是HCV慢性感染的重要原因,并且与B细胞淋巴瘤以及冷球蛋白血症具有重要相关性。

Nosocomial infection also affected prognosis of cancer, with longer hospital stay and higher death rate. Respiratory infection was the main infection and counted for 48.72%. Monilia ranked the first in pathogenic bacteria, and the ratio between bacillus and coccobacteria showed obvious disorder.

医院感染还影响恶性肿瘤的预后,表现在受感染的患者住院时间延长、死亡率提高;感染部位以呼吸道感染为主,感染率为48.72%;引起医院感染的病原菌以念珠菌为首,杆菌与球菌比例明显失调。

Although atypical lymphocytes are often present in cases of either CMV or EBV infection, the appearance of atypical lymphocytes in CMV infection may be delayed for several weeks, as appeared to happen in this case, and may persist for months.2 During the course of CMV infection in many patients, a rash develops that has been described variably as macular, papular, morbilliform, and scarlatiniform.

虽然非典型淋巴细胞的出现在两种疾病中都常见,但是在CMV 感染中可能会延迟几周出现,就如本例患者,而且可能持续数月[2]。很多病人在CMV感染病程中,皮疹形态各异,如有斑点样、丘疹样、麻疹样和猩红热样。

Logistic regression analysis and multiple factor variance analysis showed clearing degree and H2O2 concentration promoted HPV6.11/16.18 infection and speeded infection process. But pyocyte, mycetes, neuraminidase had no dependability with HPV6.11/16.18 infection.

Logistic回归和多因素方差分析结果表明,清洁度和H2O2浓度与HPV6.11/16.18感染和加速感染进程密切相关,与脓细胞、霉菌、唾液酸苷酶并无相关性。pH值、白细胞、霉菌、滴虫、线索细胞、白细胞酯酶与HPV6.11/16.18感染虽无相关性,但在引起HPV6.11/16.18感染方面起到重要作用。

Results the positive rate of hpv6.11,hpv16.18,hpv6.11/16.18 were 52(25.4%)、45(22.0%)、26(12.7%) respectivelys. logistic regression analysis and multiple factor variance analysis showed clearing degree and h2o2 concentration promoted hpv6.11/16.18 infection and speeded infection process. but pyocyte, mycetes, neuraminidase had no dependability with hpv6.11/16.18 infection.

结果 205例疑似尖锐湿疣感染患者检出hpv6.11、hpv16.18、hpv6.11/16.18阳性例数为52、45、26.logistic回归和多因素方差分析结果表明,清洁度和h2o2浓度与hpv6.11/16.18感染和加速感染进程密切相关,与脓细胞、霉菌、唾液酸苷酶并无相关性。ph值、白细胞、霉菌、滴虫、线索细胞、白细胞酯酶与hpv6.11/16.18感染虽无相关性,但在引起hpv6.11/16.18感染方面起到重要作用。

Result The incidence of SNHL in children with symptomatic cytomegalovirus infection is higher than noninfection (82.5%), majority of them was associated with hepatosplenomegaly (77.5%), pneumonia (35%). Patients with congential infection tended to have deformity (32.5%) blood system damage (15%), prematurity (12.5%), biliary tract obstruction (10%), seizures (10%). and sometimes combine with opportunistic infection (7.5%).

结果:有症状的CMV感染导致感音神经性耳聋的发病率更高(82.5%),多伴有肝脾肿大(77.5%)、肺炎(35%)、先天性感染易合并先天畸形(32.5%)、血液系统受累(15%)、早产(12.5%)、胆道闭锁(10%)、抽搐(10%),病程中可并发机会致病菌败血症(7.5%)。

Chronicity maybe result from many factors with complex mechanism.HCV may evade the host immune surveillance due to the hypermutation of HCV gene; HCV has the nature of pantropic,the tissues outside liver can provide virus for repeatedly infection of liver; The HCV receptors,such as CD81,LDL receptor,scavenger receptor B type I,L-SIGN,DC-SIGN and so on,may influence organism humoral immunity and the cellular immunity function in different degrees; HCV infection also may cause the reduction of quantity of organism immune cell or functional defect,low response of humoral immune response,tolerance of cellular immunity,then,the host finally transforms into chronic infection condition.

其慢性化的机制非常复杂,是由多个因素造成的,HCV因其基因高变性可以逃避宿主的免疫监视;HCV具有泛嗜性,肝外组织又可为肝组织的反复感染提供病毒来源;CD81、LDL受体、清道夫受体B类Ⅰ型及L-SIGN、DC-SIGN等HCV受体又可不同程度地影响机体的体液免疫和细胞免疫功能;HCV感染亦可直接导致机体免疫细胞数量减少或功能缺陷,体液免疫应答水平低下、细胞免疫耐受,宿主最终转变为慢性感染状态。

But being different from the others, drainage of the peripancreatic infection after the occurrence of SPI is very difficult, which needs many times of operation. Especially, the infection can be a vicious cycle, in which the systemic septicemia can be caused by localized infection or vice versa.

实际上,许多疾病的发生、发展和预后均与肠源性感染密切相关,但是SPI的特殊性在于发生感染后难以进行有效的手术引流、常常需要多次手术和多次置管引流,而且全身性败血症和局部感染交替出现,成为恶性循环。

The results indicated as below: 1.The total latent infection rate and infection rate of two major fungi(Alternaria alternata and Fusarium sp)was reduced effectively with preharvest BTH treatment . The latent infection rate decreased with increasing of spraying times.Results showed that the four times of treatment by BTH is the best.

结果表明: 1。采前BTH处理有效地降低了果实生长发育期间的总潜伏侵染率及两种优势病原菌(Alternaria alternata和Fusarium sp)的潜伏侵染率,控制效果随处理次数的增加而提高,以100mg/L BTH处理4次效果最好。

Conclusions\ Enhancing ICU administration in every aspect and infection surveillance, strict aseptic technique and sterilization-Isolation technique, using semisupine position, reducing unnecessary suctioning and nebulization. Avoiding the risk factors which associated with pulmonary infection was the effective method to reduce the pulmonary infection.

加强ICU全方位管理和感染监测,严格无菌技术和消毒隔离,尽量采用半卧位,减少不必要的吸痰和雾化吸入,避免肺部感染的危险因素是降低肺部感染行之有效的措施

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