查询词典 inducible

Objective: To explore the role of hypoxia-inducible factor-1α(HIF-1α) in formation of multidrug resistance induced by microenvironment and to find a new and effective molecular target on preventing and reversing chemoresistance in hepatocellular carcinoma.

目的探讨缺氧诱导因子1α(HIF-1α)在微环境诱导的肝癌多药耐药表型形成过程中的作用和地位，并为预防和逆转肝癌耐药提供有效的新的分子靶点。

Two inducible and extracellular chitosanases secreted by Penicillium sp. D-l were purified by ammonium sulfate precipitation as well as gel filtration. The purified enzymes of ChoA and ChoB had molecular masses of 93 and 21 kDa by SDS-PAGE. Both ChoA and ChoB have an acidic pH optimum, which were 4.0. The enzymes were stable over the pH range 3 to 5 for 1 h.

采用(NH_4)_2SO_4盐析法和凝胶过滤层析对Penicillium sp.D-1的壳聚糖酶进行分离提纯，得到两种壳聚糖酶，酶A经变性聚丙烯酰胺凝胶电泳分析，结果显示该酶的分子量约为93 kD；酶B经非变性聚丙烯酰胺凝胶电泳和SDS-PAGE分析，得出分子量约为21 kD。

Study the activity of inducible nitric oxide synthase in the liver of rabbits infected with Eimeria stiedai, the concentration of nitric oxide in the serum、the coccidian oosysts per gram feces ,Score the pathologies according to anatomic structures of rabiits'livers and micoscopic pathological changes. So as to study the effect of exogenous NO and NOS of the rabbits infected with E.stiedai. The results showed that when the rabbits were infected with E.stiedai, the activity of iNOS in the liver and the concentration of NO in the serum gradually increased and they both reached the peak after 12 days in the control group , GTN and GSNO groups.

为了探讨外源性一氧化氮和一氧化氮合酶在家兔球虫感染时的作用，本试验以腹腔注射的途径给予感染斯氏艾美耳球虫的家兔NO供体硝酸甘油和亚硝基谷胱甘肽，对球虫感染家兔诱导型一氧化氮合酶活性、血清中NO的浓度、每克粪便的球虫卵囊数、肝的剖检和镜下病变及其病变计分进行了研究。

COX-1 is mainly expressed constituently, catalyzing synthesized prostaglandins and participating in normal physiological processes of the kidneys, the gastrointestinal tract, platelets and other histological systems; while COX-2 is an inducible enzyme, expressed inductively under the action of stimulating factors, bacterial endotoxins, cytokines and growth factors, catalyzing synthesized PG monomer to participate in pathological molecular incidents such as regulating cell

COX-2在癌前病变组织如Barrett's综合征，肺不典型腺瘤增生，膀胱原位导管癌和光化性角化病中过度表达。

Objective To investigate the role of hypoxia inducible factor-1α(HIF-1α) and von Hippel-Lindau in murine endochondral ossification.

目的 研究低氧诱导因子1α(HIF-1a)和von Hippel-Lindau在成骨细胞水平对小鼠软骨内成骨过程的调控机制。

In eukaryotic cells,Toll-like receptors in endosomal membrane were show to recognize viral RNA in endosome and thereby initiate innate immunity pathways for virus resistance.By contrast,a cytosolic RNA receptor protein, RIG-Ⅰ(retinoic acid inducible gene-Ⅰ),has recently been identified for recognition of the viral RNA.

在真核生物体内，除了定位于内吞体膜上的TOLL样受体能够识别入侵机体的病毒RNA，启动机体抗病毒的固有免疫反应外，近年来发现了另一种能够识别病毒RNA的细胞质内受体——RIG-Ⅰ。

Purpose To study the expression of endothelia nitric oxide synthase and inducible nitric oxide synthase in breast cancer and their relationships to metastasis.

目的 ：研究内皮型一氧化氮合酶、诱导型一氧化氮合酶在乳癌中表达及与淋巴结转移的关系。

In this paper, we tried to construct an inducible transgenic expression system based on tetracycline for falciparum parasites.

本文拟建立一种抑制型疟疾四环素可诱导转基因表达系统，为研究可能在疟疾预防与治疗中有重要作用的新基因打下基础。

Id3 was originally identified as a serm-inducible immediate early gene in an established murine fibroblastic cell line.

Id3蛋白的表达和功能涉及许多复杂的调控机制，Id3在不同种类的肿瘤中具有截然不同的表达谱。

The expression of BjCHI1 was highly inducible by methyl jasmonate treatment, wounding, caterpillar feeding, and pathogenic fugal infection. These observations suggest that the promoter of BjCHI1 gene might contain specific cis-acting elements for stress responses.

BjCHI1基因受伤害、茉莉酸甲酯、虫食、真菌侵染等的强烈诱导表达，这暗示BjCHI1启动子可能含有相应的诱导元件。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。