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The rats were tested for rotational behavior induced by apomorphine for 40 min every week.

用小动脉旋转行为监测仪记录Apomorphine诱发的大鼠异常旋转行为、脑组织液生化和组织形态的变化。

At different stages (1, 3, 5, 7, 9, 11, 14, 18 and 21 d after injection), the spontaneous behavioral abnormalities were observed. the changes in the contralateral rotations induced by apomorphine and the spontaneous behavior in the rats in the open-field tests were tracked.

术后1、3、5、7、9、11、14、18和21 d,追踪观察大鼠自主行为和阿扑吗啡诱导的旋转行为变化;开野实验观察大鼠自发运动行为改变。

From the second week on, the Apomorphine induced rotation behavior is detected once a week in the second, third, and forth week after the operation.

从术后第2周开始,分别于术后第二、三、四每周一次检测动物的Apomorphine诱导的旋转行为。

From the second week on, the Apomorphine induced rotation behavior is detected once a week in the second, third, and forth week aft...

从术后第2周开始,分别于术后第二、三、四每周一次检测动物的Apomorphine诱导的旋转行为。

Four weeks following the lesions, rats were tested for apomorphine -induced asymmetric rotation.

结果是:实验组的PD鼠,在移植后的12d内旋转数比移植前明显减少,到d15后,旋转数接近移植前水平。

Methods The diabetes mellitus rat model was induced by streptozotozin, and then apomorphine was administrated to set ED diabetes model.

采用链脲佐菌素制备高血糖大鼠模型,选择符合要求的模型再用阿朴吗啡诱导,筛选出符合最终造模要求的糖尿病ED大鼠模型。

In vitro DA and its agonists apomorphine could only inhibit GTH release induced by GnRH and could not inhibit basal GTH release, the results were agreement with that in vivo.

DA不能抑制长臀鮠脑垂体碎片基础GTH的分泌,而只能抑制GnRH诱导的GTH的分泌,与在体注射的结果一致,APO的效果和DA相类似。

Results After the stimulation ,the rotating behaviour induced by apomorphine and improved distinctly, and DA content in the striatum increased (P<0.01), and Glu content reduced significantly ( P<0. 05).Content of the ASP had no change significantly.

结果 电刺激丘脑底核后,改善了PD大鼠的旋转行为,纹状体中多巴胺含量明显增加(P<0.01),谷氨酸含量明显减少(P<0.01),天门冬氨酸则无明显改变(P>0.05)。

Methods Turning tests induced by apomorphine and forelimb functional tests were performed. Also, the expression of TH mRNA in mesencephalon of the rats was detected by semi-quantitative analysis of one step RT-PCR.

利用阿朴吗啡诱发旋转试验和前肢功能试验,检测PD大鼠的神经行为学特点,一管法逆转录聚合酶链反应半定量检测其中脑TH mRNA的表达。

In addition, an expression of c-fos gene could be induced in the caudate putamen by injection of apomorphine from the rats survived 2 months in the experiment group.

免疫组化染色结果表明:6-OHDA损毁7 d,损毁侧TH阳性神经元及强阳性神经元较正常侧数目明显减少(P<0.05),但阿朴吗啡不能诱导c-fos表达。

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