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The study of Curcumine on oleic acid-induced acute lung injury in rats During the experiment, acute lung injury was induced by oleic acid in rat. The changes of dynamic lung compliance were recorded by anrise2005 pulmonary function test apparatus, light microscope was used to examine histological changes and lung index as well as wet to dry weight ratio was calculated by weighting method.

急性肺损伤是由多种原因引起的以肺泡毛细血管膜通透性增高为特征的肺损伤，是临床重症监护病人主要的死亡原因，死亡率达到30%-50%，其严重形式是急性呼吸窘迫综合症，迄今仍无有效治疗ALI和ARDS的方法和药物。

Methods Human monocyte cell line THP-1 was cultured and induced to macrophage by PMA treatment. The effect of 9-cisRA on the differentiation induced by PMA was studied. Cell morphology was observed by phase contrast microscope and the adhesion rate of THP-1 was detected by methyl thiazolyltetrazolium assay. The cell surface markers involved in differentiation of mono cyte/macmphage (CD11b, CD36) were analyzed by flow cytometry.

体外培养人单核细胞系THP-1，经佛波酯诱导分化为巨噬细胞，同时给予9-顺式维甲酸对佛波酯诱导分化进行干预，通过相差显微镜观察细胞形态，MTT比色法检测细胞贴壁率，流式细胞仪检测与单核／巨噬细胞分化有关的细胞表面标志物CD11b和CD36的表达。

METHODSMice with swelling of the earflaps induced by xylene, proliferation of granulation tissue induced by cotton pellets were treated with ethanol extract of the walnut leaf, and the weight of immune organ was weighed.

方法］采用二甲苯致小鼠耳壳肿胀，植入棉球致小鼠肉芽组织增生及称取免疫器官质量等方法，观察核桃叶乙醇提取物对小鼠抗炎作用及对免疫器官质量的影响。

Objective: To study the changes of intracellular free Ca2+ levels in 3T3 cells induced by electrets and discuss the relationship between electrets induced apoptosis of 3T3 cells and the changes of free Ca2+ levels.

目的：研究驻极体对3T3细胞内游离Ca2+浓度变化的影响，探讨驻极体诱导3T3细胞凋亡与游离Ca2+浓度变化之间的关系。

The effect of AA on BEL-7402 was not significant; However, AA could effectively enhance AT-induced hepatocarcinoma cell apoptosis and lesion severity through activation of caspase-3 but not ERKs-Conclusion; Caspase-3 and ERKs proteins could involve in arsenic-induced hepatocarcinoma cell apoptosis and differentiation respectively as intracellular signaling molecules; The effect between AT and AA on hepatocarcinoma is synergistic, which further inhibits cell growth and induces apoptosis in human hepatocarcinoma cells through activation of caspase-3 but not ERRs.

AA对BEL-7402无明显的作用，但能有效的通过caspase-3而不是ERKs的激活促进AT对肝癌细胞的凋亡效应。结论：ERKs和caspse-3信号蛋白可能分别参与了砷剂诱导的人肝癌细胞促分化和凋亡效应，AT和AA对肝癌细胞的作用有协同性，他们通过caaspase-3而不是ERKs的激活进一步抑制了肝癌的生长，诱导其凋亡。

Object to investigate the diagnosis value of Fibro Index and APRI and its consociation in hepatitis B induced hepatic fibrosis,To develop noninvasive method for detecting the severity and activity of the patients with hepatitis B induced hepatic fibrosis.

中文摘要目的：通过分析Fibro Index和APRI及其联合应用对慢性乙型肝炎患者肝纤维化的诊断价值，从而为临床评估慢性乙型肝炎肝纤维化提供简单、可靠的无创性诊断方法。

Clue to: the exercise-induced lower hemoglobin during the five-week endurance training was not induced by iron deficiency.

提示：本研究中出现的运动性Hb降低并非铁缺乏所致。

The results indicate that when soil and pile are same, the shear stresses between pile and soil under the ultimate situations of different modes are different; the negative friction on pile induced by surcharge is maximum; and the negative friction of uplift pile is minimum; the friction of pile top induced by pressing pile and bottom-loaded pile is between them.

结果表明，同种土体和桩体条件下，各种模式达到极限状态时桩－土间剪切应力不同，堆载作用下负摩擦力值最大，抗拔桩负摩阻力值最小，桩顶受压桩、托桩的摩阻力值介于其间；桩材泊松比在0.15~0.35范围内时，桩侧摩阻力随泊松比的增大而增大。

Objective To study the protective effects of imipramine on glutamate-induced neurotoxicity in cultured rat cerebral cortical neurons.Methods Cortical neurons of fetal of rat were cultured in vitro.The protective effects of Imi on glutamate-induced neurotoxicity were obserced.

目的 研究米帕明对谷氨酸损伤培养鼠皮层神经细胞的保护作用方法分离培养15～18 d胎龄的大鼠神经细胞，加入谷氨酸，观察谷氨酸对神经细胞的损伤作用及米帕明的保护作用。

The results showed the appropriate concentration of taxol (10 μM) or taxotere (35 μM) activate the influxes of H+, ROS accumulation, PAL activity and biosynthesis of taxol, as well as apoptosis, however, the high concentration taxol or taxotere (140 μM) did not show above results. Ten plots of protein were only observed in taxol-induced cells and there were differences at expression level of some plots between control and taxol-induced cells using two dimension electrophoresis, which reflect those differential protein were highly relevant to signal moleculars of cell defense responses, suggesting cell apoptosis and taxol biosynthesis might be parallel or two events in the same pathway of defense responses.

采用二维凝胶电泳技术，分析了taxol诱导细胞产生早期防御响应的蛋白表达差异，发现taxol诱导了10个新蛋白点的表达，其中一些新蛋白点的分子量与细胞信号分子G-蛋白、Ca2+依赖蛋白激酶的分子量接近。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。