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ResultsThe PSAR obviously suppressed the mice's auricle swelling induced by xylene, reduced the number of mice's spraining body induced by acetic acid, increased their latencies of spraining body and stimulation of hot board, and improved their pain threshold value.

结果制川乌能明显抑制二甲苯所致小鼠耳廓肿胀；显著减少醋酸所致小鼠扭体次数，延长小鼠扭体潜伏期；明显延长热板刺激小鼠舔足潜伏期，提高热板小鼠痛阈值。

Aloe-emodin blocks PHA-induced proliferation of T lymphocytes and the mechanism for this may be due to its inhibition on PHA-induced [Ca_(2 )]_imobilization.

结论芦荟大黄素可抑制T淋巴细胞增殖，其作用机制可能与抑制淋巴细胞内[Ca2 ]i升高相关。

MethodsThe pharmacological effects of the Ziziphus jujube leaf extract on the autonomic activities of mice, the time of sleep induced by pentobarbital sodium, the sleeping synergistic action of mice with barbital sodium at sub-threshold and hypnotic dosages and the central inhibitory effects in mice induced by amphetamine were investigated.

目的观察酸枣叶提取物对中枢神经系统作用。方法考察酸枣叶提取物对小鼠自主活动的影响、对延长戊巴比妥钠诱导的小鼠睡眠时间、对阈下巴比妥钠的睡眠协同作用以及对苯丙胺中枢兴奋作用的影响。

The blood glucose levels in many strain animal models were determined after oral administration, with the models of diabetes induced by alloxan, of hyperglycemic mice induced by epinephrine and glucose, and normal mice.

采用四氧嘧啶所致糖尿病模型、肾上腺素和葡萄糖引起的高血糖小鼠模型，以及正常小鼠口服给药，测定各模型小鼠的血糖水平；并对GXTF进行了急性毒性试验。

The deflection induced by creep is based on effective modulus method and the deflection induced by shrinkage is directly computed.

论文同时对现行规范方法和文献方法进行了分析，现行规范中考虑收缩和徐变的计算方法不全面，且偏于不安全，而文献的其它方法在收缩变形分析中也存在一些不足。

The coagulating effect of the two proteinases and their mixtureon 7S and 11S was compared. Results indicated that two proteinases interacted witheach other during the coagulating process. 11S gel induced by mixture of twoproteinases was more elastic, and 7S gel induced by separated proteinase was moreelastic.

然后采用SP-sepharose阳离子交换剂从木瓜蛋白酶分离出2种蛋白酶组分，对比它们单独作用和复合作用于7S和11S蛋白的促凝能力，结果表明木瓜蛋白酶中两种组分对7S和11S蛋白的促凝过程中存在协同作用，复合作用可以促使11S蛋白形成弹性更强的凝胶，而单独作用可以促使7S蛋白形成弹性更强的凝胶。

Cinnamomea, antrocamphin A was purified from previous ethanol extraction using bioactivity-guided fractionation. As results, the antrocamphin A could significantly inhibit NO and PGE2 autacoids production in LPS-induced RAW 264.7 macrophage cells. Meanwhile, the mRNA and protein expression levels of iNOS and COX-2 were inhibited by antrocamphin A in a dose-dependent manner. Antrocamphin A also reduced the translocation of NF-κB induced by LPS, which was associated with the prevention of the degradation of I-κB, and subsequently decreased p65/p50 proteins level in the nucleus. This is the first report demostrating the A.

接著并以活性为导向的分离策略，从樟芝子实体乙醇抽出物中分离出具抗发炎活性成分antrocamphin A，续利用LPS诱导小鼠巨噬细胞（RAW 264.7）产生发炎的模式，解析antrocamphin A之抗发炎机制，结果证实antrocamphin A确可有效抑制一氧化氮自由基和前列腺素的生成，透过蛋白质表现分析得知，antrocamphin A之抗发炎活性是经由抑制一氧化氮生成酵素和第二型环氧酵素的mRNA表现，进而抑制了一氧化氮生成酵素、第二型环氧酵素和核转录因子-κB等酵素之表现。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

Similarly, after microinjection of glucocorticoid or mineralocorticoid into bilateral rVLM with the pretreatment of DKJ-21, the elevation of BP, HR and the pressor response induced by the dPAG stimulation was abolished, which suggested that adrenal corticoids may exert their effects on the incidence of stress-induced hypertension through their modulation onto the muscarinic recptors in the rVLM.

再进一步的实验表明，以DKJ-21预先处理的正常血压大鼠，由双侧rVLM分别微量注射肾上腺糖、盐皮质激素引起的升压、加快心率、以及增强防御性升压反应的效应也能被全部阻断，提示肾上腺皮质激素在rVLM增强心血管活动以及在应激致高血压发病机制中的作用可能是通过对该部位有关心血管神经元细胞膜上M-受体的调节作用而实现的。

The results showed that thrombin elevated the activity of RhoA and the binding capability of RhoA with mDia1 during thrombin-induced platelet aggregation and spreading on Fg coated coverslips. Wortmannin inhibited the rising of RhoA activity and the binding level of RhoA with mDia1 induced by thrombin.

结果表明：凝血酶能够诱导聚集血小板中RhoA活性上调，且与mDia1相结合的RhoA-GTP显著增高；渥曼青霉素能够阻断由凝血酶诱导的聚集血小板中RhoA活性上调，并阻断凝血酶诱导的RhoA-GTP与mDia1的结合。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。