查询词典 induced current

In this thesis the process of constructing the non-perturbative Hamiltonian theory is de-scribed and is applied to estimate the vacuum condensate. It contains the following contents:At the very beginning, by using the path integral method and eliminating the gluon freedom, aGCM action 〓 of current quarks including lower order current-current coupling was derivedfrom the QCD Lagrangian and the effective Hamiltonian operator that could hardly be doneby the normal methods was derived. After doing this, the broken vacuum is introduced whichincludes quark-antiquark condensate through the generalized Bogoliubov-Valatin transformation,the effective Hamiltonian of constituent quark was derived. The detailed formulas containingthe spatial current-current coupling term for the effective Hamiltonian and gap equations wasworked out by parameterizing the correlation kernel as a quadratic potential. And then, the gapequation was solved and the quark-antiquark condensate of vacuum was studied both in the casesof instantaneous interaction and retarded interaction. In the end, the effective Hamiltionian withtwo-body quark-quark interaction was derived with one-body approximation, and with the helpof the functional integral method the coupling non-linear dynamic equations for systems withnuclear matter was derived. Finally, these equations were solved by selfconsistent method andthe effect of nuclear matter on vacuum condensate was studied. The spatial current-current coupling term is too difficult to handle, hence the correlationkernel is assumed to be not important and usually omitted in the pure vacuum condensate, andthe instantaneous interaction generally is adopted. Retaining the spatial current-current termand partial retardation effect, the quark pairs condensate in pure vacuum was studied, and theeffect of quark mass was also studied. At present, little study is focused in the case with nuclearmatter and spatial current-current term also omitted. Under the approximation with partialspatial current-current term, the effect of nuclear matter on vacuum condensate was studied.

本论文描述了量子色动力学整体色对称模型哈密顿量方法的构建过程，得到了反映正反夸克对凝聚真空结构的关于组分夸克的有效哈密顿量算符，它隐含了胶子作用，并且准确至流-流耦合项；接着，通过参数化哈密顿量中的夸克作用关联核，导出平方禁闭势参数化选择的哈密顿量的具体公式和能隙方程；随后，应用公式，编程求解，考察了瞬时作用下和部分延迟作用下真空的正反夸克对凝聚，在计算中保留了空间流-流耦合作用；之后，导出瞬时势和延迟势下包含二体作用项的哈密顿量公式，并采用单体化近似，通过泛函变分方法得到核物质存在时耦合的非线性动力学方程；在保留部分空间双流耦合作用的近似下，求解核物质的动力学方程，考察核物质密度对真空凝聚的影响，以往考察真空凝聚，对关联核的选用，由于空间流-流耦合项不易处理，也认为作用不大，常忽略该项，并且常采用瞬时作用；本文保留空间双流项和部分延迟作用，考察了真空情形的夸克对凝聚，还考察了夸克质量对纯真空凝聚的影响，以往对核物质存在情形的真空凝聚考察很少，也都忽略空间流-流项，本文在考虑部分空间流-流项近似下，考察了核物质存在对真空凝聚的影响。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

Results Qidan Granules could relieve the pain caused by glacial acetic acid and heat stimuli; significantly inhibit the oxytocin-induced dysmenorrheal in mice; It also showed obvious inhibitory effects on the increased capillary permeability induced by glacial acetic acid, carrageen-induced toe edema in rats and dimethylbenzene-induced ear swelling in mice, and cotton pellet-induced granuloma formation in rats. It could also significantly inhibit oxytocin-induced dysmenorrhea in mice.

结果 奇丹颗粒能明显抑制乙酸和热刺激所致的小鼠疼痛反应；对缩宫素所致实验性痛经小鼠具有良好的镇痛作用，对乙酸所致小鼠腹腔毛细血管通透性增高以及大鼠角叉菜胶足趾肿胀、二甲苯所致小鼠耳廓肿胀、大鼠棉球肉芽肿等急慢性炎症模型均有明显抑制作用。

In this study,the muscarinic current was induced by carbachol(50 umol/ L) or GTPYB(0.5 mmol/L).The results showed that hyposmotic superfusate(202mOsmol/ L) increased carbachol-induced current by 145士27%and increased GTPYS-induced current by 183士30%;but in the presence of cytochalasirr B(cyt- B,20 umol/ L),an actin cytoskeleton disrupter,posmotic membrane stretch increased 1CC6 by 70士6%.However,hypos motic membrane tretch induced increase in 1CC6 was potentiated to 545士81% by phalloidin(20 umol/ L),an actin microfilament stabilizer.

当豚鼠胃窦平滑肌细胞的膜电位钳制在一20 m V时，灌流液中50umol/ L卡巴胆碱(carbachol ， CCh)或电极内液中0.5 mmol/L GTPYS均可引导毒覃碱电流，2 m Os mol/ L分别使其增加145士27%和183士30；当电极内液中加入20 umol/ L的细胞松弛B时，低渗牵张使1 cce只增加70士6；而电极内液中加入20 umol/ L的鬼笔环肤则使Icce增加了545士81。

Whole-cellpatch-clamp technology demonstrated that VDPG (1g/L) had notsignificant effects on the delayed-rectified K~+ current, TTX-sensitive Na~+ current and high-voltage-activated Ca~(2+) current of rat dorsalroot ganglion cells. The fast transiet K~+ current of cottonbollworm dorsal DUM cells, the fast transiet K~+ current, Na~+ current andhigh-voltage-activated Ca~(2+) current of Periplaneta Americana dorsalunpaired median cells were also not significantly affected byVDPG at the same concentration. However, VDPG had significant effecton the fast transiet K~+ current of Pieris rapae. The VES had not significanteffects on the high-voltage-activated and low-voltage-activated Ca~(2+)current of rat DRG cells.

膜片钳电生理实验显示1g／L毒囊粗毒对蜚蠊DUM神经元的快瞬时钾电流、钠电流、高电压激活的钙电流，对棉铃虫快瞬时钾电流和大鼠DRG细胞延迟整流钾电流、TTX-S型钠电流、高电压激活的钙电流均无明显作用，却对菜青虫快瞬时钾电流有明显作用；电刺激粗毒对大鼠DRG细胞低电压和高电压激活的钙通道无明显作用。

To observe pharmacological effects of Zangqingguo Houpian on antibacterial effect in vitro,2,4-dinitrophenol induced fever in rats,the croton oil induced swelling in mouse's ear and carrageen induced WBC movement in rat chest,rat granuloma induced by tampon,acetic-acid-induced twisting test in mouse and prednisolone acetate caused immunosuppressive mice.

采用体外抗菌、对2，4-二硝基苯酚所致大鼠发热、巴豆油所致小鼠耳肿胀及角叉菜胶致大鼠胸腔白细胞游走、棉球致大鼠肉芽组织增生、冰醋酸致小鼠疼痛、醋酸泼尼松龙致免疫低下等模型，观察藏青果喉片的药效学作用。

Methods Antipyretic action of CSC was observed on rabbit fever models induced by lipopolysaccharide and rat fever models induced by baker's yeast. Rat models with pedal swelling induced by carrageenin, mouse models with auricle swelling induced by dimethylbenzene and mouse models with celiac capillary hyperpermeability induced by acetic acid were used to observe the anti- inflammatory action of CSC. Its acute toxicity in mice was also evaluated.

方法］采用细菌脂多糖致家兔发热、啤酒酵母致大鼠发热动物模型，观察穿心莲软胶囊的解热作用；采用角叉菜胶致大鼠足肿胀、二甲苯致小鼠耳肿胀和醋酸致小鼠腹腔毛细血管通透性增加的动物模型，观察穿心莲软胶囊的抗炎作用，并对小鼠进行该制剂的急性毒性试验。

PAL activity, chitinase activity, total Polyphenol content and total Flavonoids content in soybean leaves induced by the same crude toxin and race were similar, it stated that the crude toxin is an important factor which can induce resistant substances, but the induced speed and the induced intensity by the crude toxin and conidium were different. Firstly, the induced speed of crude toxin which induced PAL activity and total Flavonoids content of resistant soybean varieties was faster than speed of C.

同一生理小种的粗毒素与灰斑病菌对大豆叶片内PAL活性、总多酚类含量、总黄酮含量以及几丁质酶活性等几种生化指标均表现出相似的诱导作用，由此可推断粗毒素是诱导大豆叶片内的PAL活性、总多酚含量、总黄酮含量以及几丁质酶活性产生变化的主要生物因子，只是二者在对抗性不同的大豆品种的诱导速度及强度上存在一定的差异。

The precipitate in liquor is a common problem in distilleries which have to tackle with and the frequent causations are as follows: floccule induced by three kinds of higher fatty acid ethyl ester and microthermal storage and filtration could prevent it; white flakes of precipitate induced by containers for liquor storage such as aluminous pots which produced alumina and mare nectaris which dissolved into coating and then caused precipitate; precipitate induced by undergrade additives and CP grade or AR grade additives could prevent it; precipitate induced by water quality and strict management of water quality could prevent it; precipitate induced by packing materials and the solution was acid water washing for new bottles and liquor filling after the inner of the bottles was completely dry.

白酒产生混浊沉淀是一普遍问题，常见的有絮状沉淀，主要由3种高级脂肪酸乙酯引起，可于低温贮存过滤；白色片状沉淀，由贮酒容器引起，铝罐贮酒，会产生氧化铝溶入沉淀，最好不用铝罐贮酒；酒海贮酒会溶入涂料，造成沉淀，酒海贮酒不宜过久；由劣质添加剂引起，最好使用CP级或AR级添加剂；水质引起，对水处理应严加管理；包装材料引起，新瓶应用酸性水洗，且须控干水后再灌酒。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

"Yes, now you can give yourself airs," she said, you have got what you wanted.

"对了，您现在高兴了，"她说道，这是您所期待的。

Then the LORD said to me: Rebel Israel is inwardly more just than traitorous Judah.

上主于是对我说：＂失节的以色列比失信的犹大，更显得正义。