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The PSF/TLCP, PC/TLCP blends are seen to exhibit a monotonical decrease with the amount of TLCP increased, the viscosity versus composition curves of PPS/TLCP composites, however, exhibit a minimim with the concentration of TLCP increased.

对于相对较为柔性的聚合物PSF、PC,复合体系的表观粘度随着TLCP用量的增加而降低,但对于刚性较大的聚合物如PPS,则当TLCP用量增加到某一值后,TLCP的加入反而使复合体系的粘度增大,粘度随组成的变化有一最小值。

While the pain threshold of the normal rat group was increasesd, the con- tent of 5-HT in brain stem, the content of β-END in hypothalamus, the con- tent of β-END and ACTH in blood plasma were increased as well. However, the content of β-END in hypophysis was decreased and function of cellular im- munity was increased.

电针在使正常大鼠痛阈提高的同时,脑干内5—HT、下丘脑内β—END、外周血浆中β—END和ACTH含量均增高;垂体内β-END含量降低;机体细胞免疫功能增强。

Results The IBS% value of renal cortex increased as the level of nephritic fibrosis increased.

结果 随着肾脏纤维化程度的加重其 IBS%值升高。

Results Compared with CRF group, nephrogenic hypertension of hemin group was reduced significantly at the 6th, 8th, 10th week after operation, and followed with the decrease of serum creatinine, BUN,urinary protein and the improvement of nephrogenic anemia at the 10th week after operation. Hemin not only increased the expression of HO-1, reduced the expression of ET-1 in the kidney, but also increased the concentration of carbon monoxide, reduced the level of ET-1 in the plasm.

同时,在术后第10周hemin组比CRF组血肌酐、尿素氮、尿蛋白显著降低(P<0.05),贫血明显改善(P<0.05);肾组织中HO-1表达明显增加,血浆中内源性CO水平明显升高,肾组织和血浆中ET-1水平明显降低(P<0.05)。

It is found that NaOH exhibited significant cocatalytic action on the oxidation of o and p nitrotoluenes and had no cocatalytic action on the oxidation of m nitrotoluene, and the cocatalytic action of alkali NaOH increased as the concentrations of NaOH increased.

发现NaOH对氧气氧化邻、对硝基甲苯有明显的助催化作用,且碱的助催化作用随着NaOH浓度的增加而增加;而对氧气氧化间硝基甲苯则没有助催化作用。

Results showed that the combined effect of Streptomyces and Nocardia sp markedly increased the corrosion tendency of steel A3, decreased the impedance value and increased the corrosion current density of the electrode after 21 days of exposure.

结果表明,与单种菌相比,混合菌作用下试样表面的腐蚀倾向增大,阻抗值降低,腐蚀电流密度增加。

Increased seerity of heart failure or increased number of concomitant medications did not worsen persistence, but nonpersistence identified a high-risk population of patients who required special attention.

心衰恶化或治疗药物数量的增长并不使持续治疗的比例减少,但在高危病人中没有持续治疗值得特别关注。

Increased seerity of heart failure or increased number of concomitant medications did not worsen persistence, but nonpersistence identified a high-risk population of patients who required special attention.

关注早期开始治疗,合适的剂量,以及坚持用法很可能会带来远期的获益。

Fie years after initiation of treatment, 79% patients were still on renin-angiotensin inhibitors, 65% on -blockers, 56% on spironolactone, and 83% on statins. Notably, multiple drug treatment and increased seerity of heart failure was associated with persistence of treatment. Nonpersistence with renin-angiotensin inhibitors,-blockers, and statins was associated with increased mortality with hazard ratios for death of 1.37 (95% CI, 1.31 to 1.42), 1.25 (95% CI, 1.19 to 1.32), 1.88 (95% CI, 1.67 to 2.12), respectiely.

开始治疗5年后,有79%病人继续使用肾素血管紧张素抑制剂,65%用阻滞剂,56%用安体舒通,83%使用他汀类,值得注意的是,联合用药和心衰的加重同坚持治疗相关,无法坚持使用肾素血管紧张素抑制剂,阻滞剂,安体舒通,他汀类药物的病人同增加的死亡率相关,其死亡危险比分别为1.37 (95%可信区间, 1.31 - 1.42), 1.25 (95%可信区间, 1.19 - 1.32), 1.88 (95%可信区间, 1.67 - 2.12),。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果:倒置显微镜和透射电镜观察显示,经SAHA处理的细胞增殖速度显著减慢,细胞体积增大,细胞核较小,形状较为规则,核仁数量减少、体积变小,核内常染色质增多而异染色质减少,核质比例减小,细胞质内线粒体数量增多、线粒体嵴发达,高尔基体较为典型,粗糙型内质网增多,呈现出与正常上皮细胞相似的形态变化;MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用,并有明显的剂量依赖和时间依赖关系;免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达;流式细胞仪检测结果显示,SMMC-7721细胞经SAHA处理后,G0/G1期细胞明显增加,S期细胞则明显减少,细胞被阻滞于G0/G1期;RT-PCR检测结果表明,SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加,24h后更为明显。

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The split between the two groups can hardly be papered over.

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