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In this study, the genomic structure and regulatory elements of ApoD from 10 representive species including protozoan, invertebrate, protochordate and vertebrate were analyzed and compared. The genomic structure of ApoD is less conserved in organisms from protostome to deuterostome invertebrates, while it is highly conserved among chordates including amphioxus and verebrates. All four conserved cysteine residues are present in amino acid sequence of deuterostome ApoDs, while there are only two cysteine residues in amino acid sequence of protostomes ApoD. Structure divergence between protostome and deuterostome ApoD proteins suggests their function difference. The majority of regulatory elements are present in nearly all organism ApoD genes ranging from unicellular protozoan to mammals, suggesting that ApoD plays a very fundamental role, and possesses a conserved regulatory mechanism. However, there also exist some specific regulatory elements, which are present only in certain species and may perform some special roles.ApoD mRNA expression in murine NIH/3T3 fibroblasts exposed to various stresses such as as hydrogen peroxide and UV light shows dose-dependent increase. And a fly homolog of ApoD, Glial Lazarillo, whose overexpression results in increased resistance to hyperoxia as well as a extension of lifespan under normoxia and resistance to starvation without altering lipid or protein content.

本文首先从生物信息学角度对分属于原生动物、无脊椎动物、头索动物和脊椎动物类群的10种动物ApoD的基因结构及调控区的调控元件进行分析及比较，发现：(1)ApoD基因外显子-内含子结构从原生动物草履虫到原口动物再到后口动物海胆的进化过程中不保守，但在分析的几种脊椎动物中相当保守；(2)文昌鱼ApoD基因扮演从无脊椎动物到脊椎动物承上启下的角色，可能代表了脊椎动物ApoD基因原型；(3)四个半胱氨酸保守位点在后口动物中都存在，而在原口动物中只存在两个，原口、后口动物ApoD蛋白一级结构上的差异反映蛋白功能上可能也存在一定差别；(4)调控区大多数主要调控元件为不同动物共有，说明ApoD主要功能及其表达调控在进化中相当保守；(5)ApoD基因个别调控元件是随着物种进化而出现并开始发挥相关作用，如SF-1；还有一些调控元件在进化过程中还没有发现其规律，这说明ApoD某些功能和基因表达调控模式可能因物种不同而存在一定的差异。

Methods:Thirty-seven glioma specimens were classified as astrocytoma(25 cases, including 7 fibrillary cases; 6 protoplasmic cases; 12 anaplasfic cases), and glioblastoma( 12 cases,including 4 GBM cases).

37例人脑胶质瘤标本按WHO分类标准(1990)分为：星形细胞瘤(25例，纤维型7例，原浆型6例，间变型12例)，胶质母细胞瘤(12例，包括GBM4例)。

Six main categories being misdiagnosed were bone and joint diseases(39.82%), including osteoporosis, intervertebral disk hernia, bone fracture, psoatic strain and hyperosteogeny;kidney diseases（15.67%,including chronic nephritis and chronic renal insufficiency;hematologic diseases(9.38%);various kinds of infections(7.58％);heart diseases(3.60%);chronic liver diseases(1.86%).

主要误诊为6大类疾病，包括骨关节疾病(39.82%)，其中误诊为骨质疏松最多，其次为椎间盘突出、骨折、腰肌劳损、骨质增生；肾脏疾病(15.67%)，主要为慢性肾炎，其次为慢性肾功能不全；血液病(9.38％)；各类感染(7.58%)；心脏疾病(3.60%)；慢性肝病(1.86%)。

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

The comparison test and the reginal experiment of 6 new clones including Zhongcha 108 and 4 cultivars including Zhongcha 102 were carried out.

对中茶108等6个新品系和中茶102等4个品种分别进行了品比试验和区域试验。

Unreal Engine 3 is based on the Unicode character set, and has full support for 16-bit Unicode fonts and text input, including importing TrueType fonts into renderable bitmap fonts. Our games have shipped in 9 languages including Japanese, Chinese, and Korean.

虚幻3是基于&Unicode character set&所开发的，可以支持16位的Unicode字体和文本输入，包括可以将TrueType字体导入成可渲染的位图格式（周诗超：TrueType是一种微软和Apple公司共同研制的字型标准）我们的游戏引擎现在共有9种语言版本可供使用，包括日文，中文和韩文。

The first step is reviewing conventional methods of digital beam forming, including WINER method, Steepest-Descent method, LMS, RLS etc. Then , recent digital beam forming methods in the DS-CDMA mobile telecommunications systems are studied, including the algorithm based on least-squares despread respread Multi-Target array, least-squares Despread Respread Multi-Target Constant Modulus Array , Pilot bit LMS-DRMTA algorithm etc.

本文首先简介传统的DBF算法，包括维纳算法、最陡下降算法、最小均方算法、递归最小二乘算法等；然后介绍基于DS-CDMA移动通信系统的DBF算法，包括LS-DRMTA、LS-DRMTCMA导频LMS-DRMTA算法等；最后给出各种算法的仿真结果及分析。

Yles of Lyric Pieces have traits of multiplicity, which use "natural beauty" as major ride through out. The second chapter will give a cultural interpretation from the aspects of social and history background (including his own background, life environment and social situation) and social ideology including Romantism concept going deep into, Norway folk music edifying, opening and enlightening of impressionist precursor and the influence by other artistic thought.

第二章从社会历史背景(个人背景、生活环境、社会形势)和社会意识形态(浪漫主义观念的深入、挪威民间音乐的熏陶、印象派先驱的启迪、其它艺术思想的渗透)方面论述了钢琴抒情小品的文化成因，阐明了复杂的文化环境对格里格创作的影响以及抒情小品包涵的深厚的文化底蕴。

Currently, with its mature condition and complete infrastructure, more than 10 enterprises have entered the town, including China Science Research Institute Guangzhou Chemical Research Institute. A newly-risen industry products group has been formed, including vinyl esters, dimethyl ester, saleratus, degradable polyurethane foam etc.

目前开发利用条件成熟、设施完备，中科院广州化学研究所及10多家生产企业在镇内落户，已初步形成碳酸乙烯酯、丙烯酯、二甲酯以及小苏打、脂肪族聚碳酸亚乙酯、降解型聚氨酯泡沫塑料等新兴产业产品群。

Exceptional detail throughout including bed shrouding, radiator and extreme shock detail including reservoirs just behind the cab.

特殊的详细，包括整个床覆盖，散热器和极端休克详细，包括水库，仅落后于驾驶室。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。