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Result:There were 166 cases that were abnormal in 175 cases ,the incidence of peptic ulcer was 15.43%, the incidence of duodenal ulcer was higher than gastric ulcer in children.the incidence of chronic gastritis and chronic duodenitis was 94.86%, the incidence of chronic gastritis was significantly higher than chronic duodenitis, chronic superficial gastritis, bile reflux gastritis see most, chronic erosion hemorrhage of chronic gastritis and chronic duodenitis was not uncommon. Helicobacter pylori testing positive rate of 59.04%, peptic ulcer cases were all positive detection of helicobacter pylori.

结果:175例胃镜检查有异常者为166例,消化性溃疡发生率为15.43%,小儿十二指肠溃疡发生率高于胃溃疡,并以十二指肠球部溃疡多见,胃溃疡以胃窦溃疡多见,胃、十二指肠炎的发生率为94.86%,小儿慢性胃炎发生率明显高于慢性十二指肠炎,其中以慢性浅表性胃炎、胆汁返流性胃炎最多见,慢性糜烂出血性胃、十二指肠炎也不少见,幽门螺杆菌检测阳性率为59.04%,其中消化性溃疡病例检测幽门螺杆菌均为阳性。

YMDD mutation: HBV YMDD mutation were developed in 12 lamivudine recipients, whereas the treated group had no incidence of HBV YMDD variation, there were significant difference between two groups (p=0.000). YMDD mutation resulted in increase of the mean HBVDNA levels (p=0.000), but no contribution to serum ALT diversification (p>0.05). 2. Precore nt1896 mutation: Precore nt1896 mutation incidence had no difference between lamivudine recipients and objects who received combination therapy of Kidney-invigorating Granule and Marine Injection, and patients of HBeAg negative and HBeAg positive had a close incidence of precore mutation as well as. Precore nt1896 mutation had no influence on serum ALT level. The occurrence of precore nt1896 mutation contributed to serum HBVDNA load increased and worse response of HBVDNA extenuation. 3. HBV genotype: The baseline of serum HBVDNA gradually increase in turn of genotype B, genotype C and genotype B/C. Genotype B seemed to obtain higher rate of serum HBVDNA loss and HBeAg/anti-HBe seroconversion after combination therapy of Kidney-invigorating Granule and Marine Injection, differencing with lamivudine therapy.

疗效相关因素研究:1YMDD变异:对照组有12例检出YMDD变异,治疗组无1例检出,两组比较有显著性差异(P=0.000);发生YMDD变异者血清HBVDNA和ALT水平均有所升高,HBVDNA平均水平高于非变异者(P=0.000);血清ALT与非变异者无明显差异(P>0.05)。2前C区nt1896变异:前C区nt1896变异发生率在治疗组和对照组以及HBeAg阴性和HBeAg阳性患者之间均无明显差异(P>0.05);1896c变异对血清ALT水平无明显影响;治疗组发生1896c变异者,其HBVDNA平均水平较之未变异者明显升高(P<0.05),治疗后HBVDNA下降幅度明显低于未发生1896c变异者(P=0.000)。3HBV基因型:血清HBVDNA基础水平在B、C、B/C混合型间存在明显差异(P<0.05),按B型、C型、B/C混合型依次升高;治疗组HBVDNA阴转率、HBeAg/抗-HBe血清转换率,B型似乎高于C型和B/C混合型,但无统计学意义(P>0.05);对照组HBVDNA阴转、HBeAg/抗-HBe改变在B、C、B/C混合型间无明显差异(P>0.05)。

Results the risk for developing gestational diabetes mellitus was increasing with growth rate of pregnant body mass index (or=89.1274,95%ci6.2574~95.1757),pre-pregnancy body mass index (or=8.1826,95%ci7.1804~41.3126) years of age(or=2.4322,95%ci2.2815~15.2251) and having family history of diabetes(or=4.1254, 95%ci 4.0247~27.2024),but no statistical difference was observed in pre-pregnancy height.the faster women' s growth rate of body mass index in duration of increase pregnancy,the more possible who would fall in ill with gestational diabetes mellitus.conclusion the incidence of gestational diabetes mellitus was related to the growth rate of pregnant body mass index.

结果 多因素回归分析显示,孕期体质指数增加大(or=89.127?4,95%ci=6.257?4~95.175?7)、孕前体质指数大(or=8.182?6,95%ci=7.180?4~41.312?6)、有糖尿病家族史(or=4.125?4,95%ci=4.024?7~27.202?4)、年龄大(or=2.432?2,95%ci=2.281?5~15.225?1)均增加孕妇发生妊娠期糖尿病的风险;未发现身高与妊娠期糖尿病发病有关。排除孕前体重干扰后,孕期体重增长速度越快,发生妊娠期糖尿病的风险越大。结论孕期体质指数增长过快是妊娠期糖尿病的独立危险因素。

objective to study high risk population,high incidence time of traffic accident injuries,in order to provide evidence of prevention of traffic accidents.methods review inquiry,epidemiological analysis were performed.results there were 557 cases of traffic accidents before hospital in 2004.the traffic accident was the first in traumatism,the accounting for 51.86%.in 2004,the month of high incidence was july to december.people were on duty and off duty that was the high incidence time of traffic accident injuries in a day.the age of high incidence was 20 to 39 years old.the injury rate of males was higher than that of females.conclusion the measures of prevention and control are to strengthen traffic safety education,improve road safety level and quantity.

目的 了解院前急救交通事故的高危人群、高发时间,为交通事故的预防提供依据。方法采用回顾性调查方法,统计分析资料。结果 2004年1~12月我院急救中心院前急救的外伤病例中交通事故居首位,共557例,占总数的51.86%。在这一年内,以7~12月份为高发期。在一天中,人们上下班时间是交通事故高峰。以20~39岁年龄组为高危人群,在交通事故中受伤及死亡的男性比率高于女性。结论预防和控制交通事故的主要措施是加强群众的交通安全意识,提高驾驶员的安全行车意识和完善道路交通设施,确保良好的交通环境。

Results during 2003-2006,202 afp cases were reported in linyi city,no wild poliovirus was detected.these afp cases were distributed in 12 countries.the age of afp cases was mainly 0-5 years old,accounting for 83.2%,higher incidence in male than in female,the rate is 1.93:1.all afp cases were discarded poliomyelitis cases by the diagnoses group of shandong province.the rate of guillain-barre syndromein these cases was 19.9% monitored and has appraised 3 cases of vapp.the reported incidence of non-polio afp cases of children under 15 years old has been over 1/100000 since 2003.other indexes have been above 80%.

结果 2003~2006年全市共报告afp病例202例,未发现脊灰野病毒引起的病例。病例分布在全市12个县:发病以0到5岁儿童为主,占83.2%;男性发病多于女性,男女比例1.93:1;所有监测病例经山东省专家诊断组均为排除脊灰病例,格林巴利综合征最多,占19.9%,监测并鉴定了3例疫苗相关病例。

The incidences of 4 water-borne infectious diseases except bacteroidal diarrhea showed downtrends year after year in 10 past years.By relativity analyzing,there were negative correlations between overall incidences of 4 water-borne infectious diseases and the qualification rate of drinking water coliform group,between the incidence of hepatitis A and drinking water coliform, between the incidence of typhoid or paratyphoid and drinking water total plate countand between the incidence of typhoid or paratyphoid and drinking water coliform.

改水10年间四类主要介水传染病除菌痢以外均呈逐年下降趋势,经相关性分析,四类主要介水传染病的总发病率与饮用水大肠菌群、甲肝发病率与饮用水大肠菌群、伤寒副伤寒发病率分别与同期饮用水细菌总数和大肠菌群指标合格率变化之间呈负相关。

There were significant differences of the incidences of 4 water-borne infectious diseases(cholera,hepatitis A,bacteroidal diarrhea and typhoid or paratyphoid)between former 5 years and later 5 years.The incidences of 4 water-borne infectious diseases except bacteroidal diarrhea showed downtrends year after year in 10 past years.By relativity analyzing,there were negative correlations between overall incidences of 4 water-borne infectious diseases and the qualification rate of drinking water coliform group,between the incidence of hepatitis A and drinking water coliform, between the incidence of typhoid or paratyphoid and drinking water total plate countand between the incidence of typhoid or paratyphoid and drinking water coliform.

改水前后各五年霍乱、甲肝、菌痢、伤寒副伤寒等四类主要介水传染病总发病率的差异有显著性,四类主要介水传染病的总发病率与饮用水大肠菌群合格率之间、甲肝发病率与饮用水大肠菌群合格率之间、伤寒副伤寒发病率分别与同期饮用水细菌总数和大肠菌群指标合格率之(来源:A1eBC3737论文网www.abclunwen.com)间呈负相关。

At such a rate,the suffocation incidence of the newborn was about 606%,and the incidence of complication and sequelae of the puerperaants was about 5.58%.Conclusion: The perineotomy parturitono may have remarkable significance in the second course of parturition in avoiding perineum laceration,alleviating the pressure of the pelvic tissues on fetus' head,shortening the second course of parturition,as well as in decreasing the suffocation incidence of the newborn.

会阴切开阴道助产术在第二产程中为避免会阴及盆底严重裂伤,减轻盆底组织对胎头的压迫、缩短第二产程、加速分娩、降低新生儿窒息率具有很大的意义,只有合理掌握手术的指征以及避免过多干预和进行手术助产,会阴切开阴道助产术就可取得良好的效果,侧切率就能得到很好的控制,否则将会产生一系列并发症,对母婴带来很大的危害。

Results At the dosage of 25 mg/kg,AN could induce higher incidence of fetal resorption and death,and decrease the average fetal body weight and le ngth with significant difference(P<0.05)when compared with neg ative controls.At the dosage of 35 mg/kg,AN could decrease average vital fet us p er litter with significant difference(P<0.05),and induce chang es of other indexes with highly significant difference(P<0.0 1).At the dosage of 25 and 35 mg/kg,AN could induce higher teras rate,maternal t eras rate and malformation rate of vital fetus with significant and/or highly s ignificant difference(P<0.05 or P<0.01),resp ectively.There existed a dose-effect or dose-response relationship between abo ve indexes and doses.

结果 25 mg·kg-1组死胎率、吸收胎率升高,胎鼠平均体重、体长、尾长减小,与阴性对照组比较差异有显著性(P<0.05);35 mg·kg-1组除窝平均活胎数减少,差异有显著性( P<0.05),其余各指标与阴性对照组比较差异有非常显著性(P <0.01);25,35 mg·kg-1组畸胎率、母体畸胎率、活胎畸形率升高,与对照组相比差异有显著性和/或非常显著性(P<0.05或P <0.01),且有明确的剂量效应或剂量反应关系。

Objective To investigate the incidence rate,clinical characteristics and conversion of depression caused by chronic alcoholism.

目的 了解慢性酒精中毒所致抑郁症状的发生率、临床特点及转归。

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