查询词典 inactivation

Recent study showed that the devitalization of DPC4 gene was present in nearly 50% of pancreatic carcinoma, which interrupted the TGF-βsignal pathway, so inactivation of DPC4 gene maybe one of the most important cause of pancreatic carcinoma. The present study was carried out to clarify the effect of DPC4 gene on human pareatic carcinoma cell line JF305, which can help us understand the growth and proliferation mechanism of pancreatic carcinoma and provide us the practical guidance on gene therapy of pancreatic carcinoma.

最新研究资料表明近一半的胰腺癌存在DPC4(deleted in pancreatic carcinoma)失活，进而使TGF-β信号传导途径中断，失去其对肿瘤细胞的抑制作用，导致细胞过度生长和增殖，因此DPC4的改变可能是胰腺癌发生、发展的重要原因之一[2]。

The kinetics of complexing inactivation at identical enzyme and inhibitor concentrations was analyzed and the equations of product generation were derived when the free enzyme concentration is great larger or smaller than the dissociation constant of inhibitor,〓.

在游离酶浓度远大于或远小于抑制剂的解离常数的条件下，导出了产物生成的方程。

We found that after making a counter charge pair of the mutations that between F1625、I1628 and I1488、F1489,the change of inactivation curve between double mutant and the sum of single mutants is different .

我们将S4/D4上F1625、I1628位置和I1488、F1489位置做相反电性配对之后，通道的不活化曲线与单突变的和相较出现明显的变化。

One of the two X -chromosomes in cells of female is randomly inactivated in the early stage of embryological development, results in random X - chromosome inactivation pattern of tissues of normal female.

三人IN的克隆状态及其意义本研究中，CIN组的单克隆率为38.5％，高于正常宫颈组，提示一部分CIN已具备了细胞异常增殖的能力。

In eutherian mammals, XCI is thought to be triggered by the expression of the non-coding Xist RNA from the future inactive X chromosome3, 4, 5; Xist RNA in turn is proposed to recruit protein complexes that bring about heterochromatinization of the Xi6, 7. Here we test whether imprinted XCI, which results in preferential inactivation of the paternal X chromosome, occurs in mouse embryos inheriting an Xp lacking Xist.

在最新一项研究中，美国北卡罗琳娜大学研究人员用小鼠胚胎（研究人员用基因工程方法使这些小鼠在其未来失活的X-染色体上含有一个有缺陷的Xist基因）所做的新的研究工作显示，实际情况更为复杂。

Xist and Tsix are imprinted in the extraembryonic tissues of mouse embryos so that they are expressed from the paternal and maternal X, respectively, resulting in the preferential inactivation of the paternal X.

Xist和Tsix在小鼠胚胎的胚外组织中是印迹的，Xist在父本X染色体上表达而Tsix在母本X染色体上表达，导致父本X染色体的优先失活。

Frisson and Vicia hirsute, we found that inactivation of the hurL gene caused failure in inducing nodulation, whereas the same mutant complemented with an intact R.

而经野生型hurL基因互补的同一突变株在这两种植物上的结瘤数均恢复到野生型水平。

With the development of molecular biology, tumor has been identified as a kind of genic disease. The intrinsical properties of tumor are activation of oncogene and inactivation of antioncogene.

随着分子生物学研究的不断深入，肿瘤确认为一种基因病，癌基因的激活与抑癌基因的失活是其发生发展的内在本质。

Circuit breakers are the important equipments in the electric power system, which get out of order due to the inactivation in the aspect of insulation characteristic, mechanical characteristic and electric characteristic,the losses that they cause are a few thousands times more than price of themselves.

断路器是电力系统中的重要设备，在运行过程中可能发生的故障主要是机械故障与绝缘故障，由于它的故障所导致的损失可能为其本身价格的数千倍甚至数万倍，因此对断路器进行状态监测，及时了解断路器的运行状况，成为电力系统十分关注并迫切希望解决的问题之一。

The effects of different denaturants on CK and salt-induced molten globule state were studied. The results showed that arginine and aspartate caused inactivation and unfolding of CK.

在研究不同变性剂对肌酸激酶结构和活性的影响及盐诱导的熔球态时发现精氨酸和天门冬氨酸引起肌酸激酶失活和去折叠，为一级反应的一相过程。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了