查询词典 in vivo

By statistic analysis, there were significant differences with the average cell number of each morulae, early blastula and blastula between in vivo and in vitro, there were no differences with the hatching of blastula between in vivo and in vitro.

经统计分析体内桑椹胚、早期囊胚、囊胚的每一胚胎平均细胞数与体外桑椹胚、早期囊胚、囊胚的每一胚胎平均细胞数有显著差异；扩张囊胚的体内，体外每一胚胎平均细胞数没有显著差异。

Tetraploid embryos could be produced by electrofusion at the stage of two-cell embryos, which could develop to blastcysts fellowed by fusion of cytoplasm and nucleus and cleavage in vitro.After fusion of cytoplasm, the DNA methylation levels of the fused embryos was very high as well as two-cell diploid embryos in vivo.Then the embryos was rapiddly demethylated when the nucleus begin to fuse, resulting the lowest DNA methylation levels when the nucleus fused completely.After that, the DNA methylation levels of fused embryos were gradually increased until the blastocysts stage.However, whereas an asymmetric distribution of DNA methylation was established in an vivo-derived blastocysts with a higher methylation level in the inner cell mass than in the trophectoderm, in most vitro-derived tetraploid blastocysts, we can not detect the asymmetric distribution.

结果表明：利用电融合方法制备的小鼠四倍体胚胎在体外培养体系中经历细胞质融合、细胞核融合及细胞继续分裂发育直到囊胚期的过程，在细胞质融合的时候胚胎卵裂球同体内体外培养二倍体胚胎一样，呈现高度甲基化状态；在细胞核开始融合的时候，甲基化水平急速下降，在细胞核完全融合的时候甲基化水平达到最低点；随着胚胎继续分裂，胚胎甲基化水平逐渐增加，在囊胚期甲基化水平最高；但是囊胚期四倍体胚胎内细胞团同滋养层细胞甲基化荧光信号没有差别，这与体内体外培养二倍体囊胚内细胞团细胞甲基化荧光强度高于滋养层细胞甲基化荧光强度不同。

Techniques in embryo technology (such as in vitro production of embryos and animal cloning) need large quantities of high quality oocytes. But the quality of in vitro matured oocytes from slaughtered animals is generally lower than that of the in vivo matured oocytes. It is usually thought that the reason for this poor quality in in vitro matured oocytes is the lack of capacitation during the dominancy of follicular development in vivo.

目前胚胎工程技术研究和开发(如体外生产胚胎和体细胞克隆等)需要大量高质量的成熟卵母细胞，但利用屠宰动物卵巢卵母细胞经过体外成熟培养而获取的卵母细胞质量还远不如体内成熟卵母细胞，其原因一般认为是由于缺乏体内主卵泡阶段的获能作用。

The infectivity of porcine endogenous retrovirus with porcine skin fibroblast cells in vitro and in vivo were demonstrated in this study, and there is no evidence of active viral replication of PERV in vivo.

本实验证实了猪皮肤成纤维细胞PERV的体外感染性和在小鼠体内的感染性，但未能找到PERV在体内活跃复制的明显证据。

The reproductive toxicity of Aroclor 1254 on the oogenesis, the fertilization and preimplantion embryonic in vivo in female mice, the spermatogenesis toxicity, the sperma fertilizing ability and the zygote developmental toxicity in vivo in male mice were studied, and the toxicity mechanism were discussed by histopathological examination of the ovary, the uterus, the testis and epididymides.

以小鼠为动物模型，研究了类二噁英多氯联苯的典型代表物质——Aroclor 1254对母鼠卵子发生、受精和附植前胚胎体内发育毒性，公鼠精子发生毒性，以及对精子受精能力和受精卵体内发育的毒性。

For the first time in the world, an in vitro testing model based on FRTL-5 cell line for thyroglobulin disruptors was established, as well as an in vivo testing model acting as a compensation for the in vitro method. The feasibility of the combination of in vitro and in vivo screening methods was discussed, as well as the mechanism of thyroid hormone disruptors.

为达到这一目的，我们在国内外率先建立了FRTL-5细胞对干扰甲状腺球蛋白的化学物的体外甄别方法模型，并建立相应的体内动物实验模型以弥补体外甄别方法在特异性上的不足，探讨以此建立体外、体内试验相结合的甄别方法体系的可行性，同时初步探讨甲状腺素干扰物的作用机制。

In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上，为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现，本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点，分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点；其次，糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降，这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足，继发伤口难愈？

Methods Both in vitro and in vivo models of ventilator-induced lung injury were used. Alveolar epithelial cells were stretched in vitro to mimic the lung injury in VILI. Rats were ventilated at large tidal volume to produce ventilator-induced lung injury in vivo. A total of 23 inflammatory cytokines were screened with micro gene array in stretched alveolar epithelial cells.

方法通过呼吸机诱导肺损伤的体内及体外模型，将分离的肺泡上皮细胞于体外拉长，利用基因微阵列技术分析并筛选出上调的炎性细胞因子，之后给予大鼠呼吸机机械通气，留取血清标本，测量这些细胞因子在血清中是否上调。

The significant linear correlation existed between the dissolution in virtro and the absorption in vivo (P＜0.01). CONCLUSION: The size distribution of FP-GMS was focalizing,and FP-GMS had obviously sustained effect in vitro and in vivo.

本法制备的氟比洛芬明胶微球粒径分布集中，粒径大小符合设计要求，体内外释药结果表明氟比洛芬明胶微球具有明显的缓释作用。

Bioreactor is a kind of device intended for in vitro tissue culture that incubates the cells or tissues taken from living bodies in simulated physiological environment in vivo. On the basis of original cell culture, the present bioreactors apply biomechanical stimulation to simulate the stressed environment of articular cartilage in vivo.

生物反应器是一种体外的组织培养装置，它将活体内取出的细胞或组织在模拟体内生理环境下进行孵育培养使之生长分化，现有的生物反应器主要是在原有细胞培养的基础上加以力学刺激以模拟关节软骨在体内的应力环境。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。