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Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73~79. The fragments of abnormal alleles were 380~402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18~40, fragments from 202~270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变,CAG三核苷酸重复73~79次,异常等位基因片段长380~402bp,均为杂合子;正常人CAG三核苷酸重复18~40次,等位片段长200~270bp,电生理发现MJD的SCV减慢比MCV明显,而下肢的MCV、SCV又较上肢明显,BAEP、VEP均有不同程度的潜伏期延长或波的异常;MJD的父亲遗传早于母亲,进展也较块,临床以小脑性共济失调为突出症状,其次为构音障碍、突眼等,肌肉萎缩仅见于晚期病人;MRI示小脑萎缩较明显,脑干萎缩并不严重,未见明显的颈髓萎缩。

In all else, he thought, she was like the Starrs--in her large, purplish-grey eyes with their very long lashes and black brows, in her high, white forehead--too high for beauty--in the delicate modelling of her pale oval face and sensitive mouth, in the little ears that were pointed just a wee bit to show that she was kin to tribes of elfland.

在所有其他方面,他想,她就像斯塔尔家族的——大大的紫灰色眼睛,带着长长的睫毛和乌黑的眼眉;高高的洁白的额头——基于美观角度似乎过高了一些;曲线优美的椭圆形的苍白脸颊;敏感的嘴唇;小小的耳朵有一点点尖,表明她和精灵部族的血缘关系。

Statistics data show that in Beijing in recent years of housing in the fold 3,040 yuan / square meters, less than 3,000 yuan eyeful eyes / m2 property is minimal.

统计局的数据表明,北京这几年经济适用房的均价在3040元/平方米左右,满眼看去低于3000元/平方米的楼盘真是微乎其微。

She Walks In Beauty by George Gordon, Lord Byron She walks in Beauty, like the night Of cloudless climes and starry skies; And all that's best of dark and bright Meet in her aspect and her eyes: Thus mellowed to that tender light Which Heaven to gaudy day denies.

她在美中行走--拜伦她在美中行走,像黑夜晴朗无云,满天星斗闪耀,黑暗和光明中美好的一切都溶入她的容颜和双眸:那光辉如此柔和清洌,俗丽的白昼得不到造化的关照。

George Gordon Byron 乔治-乔登-拜伦《春逝》 She Walks in Beauty She walks in beauty, like the night Of cloudless climes and starry skies; And all that's best of dark and bright Meet in her aspect and her eyes: Thus mellow'd to that tender light Which heaven to gaudy day denies.

翻译如下:她走在美的光彩中一她走在美的光彩中,象夜晚皎洁无云而且繁星漫天;明与暗的最美妙的色泽在她的仪容和秋波里呈现:耀目的白天只嫌光太强,它比那光亮柔和而幽暗。

I'm stuck on your heart, i hang on every word you say Tear us apart, baby i would rather be dead In your heart i see the start of every night and every day In your eyes, i get lost, i gte washed away Just as long as i'm here in your arms i could be in no better place...

我在你的心上被欺骗,我悬挂在你说的每个字上分别地流泪我们,宝贝我宁愿死在你的心我中见到开始每个夜晚和每天在你的眼睛中,我迷路,冲走的我 gte 正如只要我在你的双臂我中在这里可能是在没有较好的地方中。。。

Person seen to know how can realize experience in the deep and serious expression in one's eyes of man, no matter those experiences are grieved or joyful, all that men consider oneself in sacred history.

懂看的人能体会到厚重男人的眼神里的经历,无论那些经历是伤痛或愉悦,都是男人自视神圣的历史。

In tranquil night I in stares at to look at sky star view month circle content perhaps in this Christmas day I did not look that snowflake actually may feel same cool perhaps in this Christmas day I did not look that family member actually may feel same kind perhaps in this Christmas day my hear laughter actually may feel same happy perhaps in this Christmas day I do not hear comfort actually to be possible to feel same warm joyful I dark to see society happy equally has also liked with mine both eyes retaining I like feeling which celebrates liking my today's feeling offering for friend of mine listen ........................ that tune tune music to resound in the sky to look ........................ that star, in the clouds see pace back and forth Christmas day in we to be possible to see lovers connecting rod waited for together in the sky the snowflake falls gently Christmas day in we to be possible to hear the friends to wait for hoped together in the time vainly hopes for realizes I to want well to use my this blessing heart to open better smoother which front you path enables you to be possible to walkI good want to use heart which my this double feels grateful to lead you to realize vainly hoped for that enables you to be possible live each US more joyful Christmas day's today I for your these my life in friend to pray hoped in the new year safe joyful happy Christmas day's today I pray for heavenly blessing for your these my life's in friend to hope in the new holiday happy beautiful intoxicant.

在宁静的夜晚我一个人在凝望看天空星斗观月圆美满也许在这一个圣诞节我看不到雪花却可以感受一样的清凉也许在这一个圣诞节我看不到亲人却可以感受一样的亲切也许在这一个圣诞节我听不到笑声却可以感受一样的欢乐也许在这一个圣诞节我听不到安慰却可以感受一样的温欣我冥冥中看到了人世间的欢乐也一样喜欢用我的双眼保留我喜欢喜庆的感觉喜欢把我今天的感觉奉献给我的朋友听……………………那一曲曲音乐在天空中响起看……………………那一颗颗星星在云朵见徘徊圣诞节里我们可以看到恋人们牵手一起等待天空中雪花的飘落圣诞节里我们可以听见朋友们等待一起盼望时光里梦想的实现我好想用我这颗祝福的心来开启你们前方的道路让你们可以走的更好更平坦我好想用我这双感恩的心来带领你们实现梦想让你们可以活的每美更快乐圣诞节的今天我为你们这些我生命中的朋友祈祷希望新的一年里平安快乐幸福圣诞节的今天我为你们这些我生命中的朋友祝福希望新的节日里开心美丽醉人

Reversal of papilledema changes in the optic disc to normal indicates the anatomical recovery, while reduction of enlargement of blind spot to normal size, recovery of red green deficieny to normal colour vision in both eyes and visual improvement after regression of papilledema in right eye indicate functional recovery in this patient.

抗磷脂综合征应与视乳头水肿鉴别诊断;对于顽固性的视乳头水肿,口服乙酰唑胺是抗凝治疗的重要辅助治疗,它可以保护视神经免受有可能导致失明后果的视神经损害。

Methods Fundus photograph,fundus fluorescein angiography and indocyanine green angiography were performed in a series of 70 patients with unilateral AMD and drusens and pigmentary changes in the macular region in contralateral eyes.

对70例一眼为湿性型AMD的患者对侧眼作眼底彩色照相、荧光素眼底血管造影(fundus fluorescein angiography,FFA)以及ICGA检查,并对其眼底荧光图像进行比较和分析。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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