查询词典 in situ

The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明，SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达，孔圣枕中丹组比盐酸哌甲酯组要高，且两者均低于对照组；豆状核多巴胺受体D2的基因表达，盐酸哌甲酯组要比孔圣枕中丹组高，且均低于对照组。

Results Although overexpression of P53 protein was not detected in normal eyelid cutaneous epithelium, meibomian gland and mild epithelial dysplasia, the positive rate of P53 increased in degree in moderate and severe dysplasia, carcinoma in situ and invasive tumors, and PCNA labeling index progressively increased too. Overexpression of P53 protein was detected in 30/53 cases of basal cell carcinoma, 16/32 cases of squamous cell carcinoma, 10/17 cases of meibomian gland carcinoma, and the intensity of P53 protein immunostaining increased with the lowering in the degree of histological differentiation.

结果 在正常眼睑皮肤、睑板腺及轻度不典型增生眼睑上皮中，未见P53蛋白表达，而中、重度不典型增生，原位癌，浸润癌中，P53蛋白阳性表达率逐渐增高，其 PCNA指数也有增加趋势。30/53例基底细胞癌(basal cell carcinoma，BCC)、16/32例鳞状细胞癌（squamous cell carcinoma，SCC）、10/17例睑板腺癌中，P53蛋白阳性表达；同时，随着肿瘤组织分化程度的降低，P53蛋白阳性表达程度有逐渐增高的趋势。

A cDNA segment was isolated from M. meretrix larvae. The results of caspase in situ detection in larval developmental stages revealed that there were activated caspase from L1 to L3, indicating caspase is involved in the whole developmental process. The main apoptosis area was found in velum at L3 before metamorphosis, indicating the degradation of velum might be the process of apoptosis. The larvae before metamorphosis were treated by caspase specific inhibitor to analyze the role of caspase in this process. The results indicated that caspase have function metamorphosis.

根据caspase在不同物种中的保守区域设计简并引物，在文蛤幼虫中扩增到cDNA序列片段；检测有活性的caspase在文蛤幼虫各发育时期的分布部位，发现其在L1至L3期幼虫中都有分布，说明整个幼虫形态变化过程中都有caspase的参与；细胞凋亡检测结果显示，幼虫主要发生细胞凋亡的部位在L3期幼虫的面盘，即变态过程中要退化的器官，说明细胞凋亡可能是文蛤幼虫变态过程中面盘退化的主要机制；用caspase特异性抑制剂处理变态前幼虫，发现幼虫变态率下降，初步验证了caspase在文蛤幼虫变态过程中的作用。

In situ hybridization using biotinylated POMC cRNA probe made it possible to localize POMC mRNA in the rat ovary. POMC mRNA predominantly existed in corpora lutea of diesturs, pregnant and pseudopregnant rat ovaries. POMC containing cells scattered in the ovarian intertitium were seen. The amount of POMC mRNA in granulosa cells was negligible.

采用生物素标记的POMCcRNA作为探针，进行原位杂文，研究POMCmRNA在大鼠卵巢中的分布，实验表明，POMCmRNA主要分布于间期，妊娠和假孕大鼠卵巢黄体中，间质细胞也可见少量POMCmRNA，而卵泡颗粒细胞中POMCmRNA极少。

Pure-remote sensing information models are free of the numerous distributional parameters that are difficult to obtain in vast area. The following sections are included in the study.(1) The VCI and SVI based on time-series NDVI data are used to analyse regional drought and the following results were reached: As the vegetation growth status index, the response of VCI and SVI to precipitation was land cover type, temporal and site specified. So VCI and SVI have little information about drought when used to monitor regional drought especially in China that has a mountainous topographty.(2) Based on the interpretation of NDVI-Ts space, NDVI and land surface temperature was combined to construct NVDI-Ts space from which the TVDI (Temperature Vegetation Dryness Index) was obtained with line ratio method and normalized slopes method. When compared with the topsoil moisture measured in situ, TVDI are competent in regional drought monitoring. Illumed by the NDVI-Ts space, we combined the NDVI with day/night land surface temperature difference and apparent thermal inertia to construct NDVI-ΔT and NDVI-ATI spaces from which the DVDI and AVDI were estimated respectively with 8-day composite MODIS 〓 product and 16-day composite MODIS NDVI product.

具体包括以下几方面的内容：(1)VCI和SVI在干旱监测中的作用评价：探讨利用NDVI时间系列数据建立的植被状态指数和标准植被指数评价区域干旱的可行性，研究结果表明：VCI和SVI作为植被相对生长状况指标，对降水的响应随着植被覆盖类型、时间和空间等而表现出不同的敏感性，因此在大区域干旱监测中，特别是我国这样地形复杂多样的国家，VCI和SVI在干旱监测中的作用都是有限的；(2)利用TVDI评价全国干旱等级分布：结合陆地表面温度和植被指数建立NDVI-T〓空间，在NDVI-T〓空间物理意义理解的基础上，分别采用线段比值法和斜率归一化法构建温度植被干旱指数，并利用TVDI研究了我国2000年3～5月份各旬的干旱分布，取得比较满意的结果。

The results of in situ hybridization showed that the gene of Mdde was expressed mainly in epidermis of the body wall and fat bodies, and no expression signal was detected in tracheae, intestine and musculature. The gene of Mdde in epidermis expressed both in challenged larva and no-challenged larva, whereas the gene of mdde in fat body expressed only in challenged larva.

原位杂交的结果表明：Mdde基因在家蝇幼虫体内主要表达于表皮和脂肪体，在气管、肠和肌肉组织中没有检测到Mdde基因的表达；表皮中Mdde基因在微生物刺激前后均有表达，而脂肪体中Mdde基因经微生物刺激后才表达，刺激前不表达。

In this project, the selection criteria of matrix and reinforcement for obtaining composites with high strength and toughness are determined. The as-cast and aged microstructures of composites reinforced with particles of different strength are observed, and their metallurgical conditions and stabilization mechanisms are analyzed. The aging precipitation behaviors and mechanisms are studied. Some characteristics of nano-materials (micro-distortion areas) are found in 150nm- Al2O3p/Al composites and their formation mechanisms are expatiated. The "flexible" restriction to the deformation of the matrix by low strength AlN particle is observed by in-situ TEM and SEM techniques, and the mechanisms of its resist on cracks propagation and its contribution to composite strength are revealed. The high temperature deformation behaviors of Al2O3p/Al composites are studied. A rare-earth coating is established on sub-micron Al2O3 particles, leading to an improvement in wettability between coated Al2O3 and liquid aluminum and a decrease in infiltration pressure. The strength and ductility of coated particles reinforced composite are also increased. The interfacial characteristics, bonding structures and their formation mechanisms are studied, and the crystal orientation relationships between reinforcement particles and aluminum matrix are investigated. Finally a lighter composite with better balance of strength and damping properties is reinforced with hollow ceramic microballoons of ultra-lower strength.

本项目发现了获得高强度和高韧性复合材料的基体、增强体选择依据；观察了各种强度质点增强复合材料的铸态和时效态微观组织，分析其微观结构形成的金属学条件及稳定性机理，研究了其时效析出规律和时效机制，发现了150nmAl2O3颗粒增强铝基复合材料基体中的纳米材料特征，并解释了其形成机理；利用TEM和SEM动态拉伸技术发现了低强度质点AlN颗粒对变形协调的&柔性强化&机制，揭示了其对裂纹扩展的阻碍作用和对复合材料高强度的贡献；研究了中强度质点的Al2O3颗粒增强铝基复合材料的高温变形行为，并对其进行了稀土界面层设计与制备，改善了颗粒与铝合金之间的界面润湿性，降低了复合材料铸造渗透压力，提高了复合材料的强、韧性；研究了多种复合材料界面结构及形成机理，确定了增强体与基体之间的界面结合机制，分析了复合材料界面处的晶体学位向关系；最后制备了含微孔的中空型陶瓷颗粒增强的特种复合材料，得到了强度和阻尼综合性能较好的轻质复合材料。

Diabetes mellitus is a kind of chronic and worldwide disease, and tight glycemic control is critical in manging DM and preventing complications such as nephropathy, neuropathy and retinopathy. In order to relieve DM patients pain and decrease the risk of crossinfection, noninvasive ways to monitor blood glucose concentrations are preferred, and one approach is to monitor glucose concentrations in tear fluid. This review covers recent understanding of features of tear fluid and relevant changes in DM, the influence of different collecting methods in tear glucose concentration, and attempts to monitor tear glucose concentration in situ by using contactlens based sensing devices.

糖尿病（diabetes mellitus，DM）是一种慢性疾病，也是一种全球性疾病，糖尿病患者长期理想控制血糖有助于防止或延缓糖尿病肾病、神经病变和糖尿病视网膜病变等慢性并发症的发生，为了减少患者的痛苦和降低交叉感染发生的危险，人们想到了通过泪糖浓度这一无创指标来监测血糖控制情况的可能性，我们综合近年的相关研究进展，从泪液的特性及糖尿病患者的相关改变、不同收集方法对泪糖浓度的影响及检测泪糖浓度的产品等方面进一步探讨泪糖浓度作为糖尿病病情评价指标的可行性。

Rresults from those studies can be summariazed as follow:(1) A preliminary study no correlationship between the UV-VIS reflection spectrum of tomato fruit surface and the lycopene amount of tomato fruit was undertaken. Based on observation from this study, a damage-free and in-situ detection technique of lycopene amount from tomato was developed with UV-VIS reflection spectroscopy;(2) The geometrical isomers of lycopene were separated successfully on C30-HPLC-PDA-ELSD. The absorption coefficients of Z-isomers were consequently dedermined. The geometrical isomer composition of lycopene could therefore be assessed. Those efforts formed a solid base to identify the natural product from synthetic compound of lycopene;(3) Lycopene resource from the fruit of Autumn oliver was proved to be available for industrial application. An extraction methos of lycopene from the fruit of Autumn oliver by supercritical carbon dioxide was developed at laboratory scale;(4) A method to extract lycopene by supercritical liquid with improved efficiency was developed; Data from this investigation suggested that a proper raw material pre-extraction process was important for a better extraction efficiency;(5) Variation in the geometrical isomer composition of lycopene during its metabolish in rat was assessed. A large amount of Z-isomers were observed. This variation took place in serum;(6) The absorption rate and accumulation in serum of natural lycopene in rat were assessed;(7) Ability to quench singlet oxygen by different geometrical isomers of lycopene was compared;(8) It was detected that whether natural lycopene had functions to regule blood-lipids and LDL antioxidation;(9) A C31 degradation piece of lycopene was found in the prostate gland of rat.

研究结果包括：[1]应用UV-VIS反射光谱法建立了番茄果实中番茄红素含量的无损伤、现场检测技术；[2]应用C30-HPLC-PDA-ELSD技术实现了对番茄红素几何异构体的分离，测定了不同顺式异构体的吸光系数，建立了天然番茄红素几何异构体组成的检测方法，为区分和鉴定人工合成品和天然产物奠定了基础；[3]证实了秋橄榄果实中的番茄红素资源具有工业开发价值，并建立了超临界CO_2萃取的实验室方法；[4]探索了提高番茄红素超临界流体萃取效率的方法，证明了物料前处理对提高萃取效率起了极其重要的作用；[5]观察了番茄红素在大鼠体内几何异构体组成的变化情况，发现了大量顺式异构体的存在，并证实了几何异构体组成在血清中发生了显著变化；[6]测定了天然番茄红素在大鼠体内的吸收率和在大鼠血清中的动态积累规律；[7]比较了不同番茄红素几何异构体淬灭单线态氧的能力；[8]检测了天然番茄红素是否具有调节血脂作用和抗低密度脂蛋白氧化的功能；[9]首次发现大鼠前列腺内存在番茄红素C31降解片段，并证实其仍具有淬灭单线态氧的能力。

The stresses in cast-in-situ slab and wall of residence house that is produced by thermal dilatation in material and the shrinkage in concrete will result in cracks and affect structure' s safety severely.

住宅结构中的现浇楼板、墙体由于材料热胀冷缩和混凝土收缩产生温度应力和收缩应力，可能会导致构件开裂，严重时甚至影响结构的安全使用。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐