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"Apraclonidine, a selective alpha-2-agonist, was developed to lower intraocular pressure and minimize the systemic side effects associated with the use of its parent drug, clonidine," write Patrick Watts, MBBS, MS, from the University Hospital of Wales in Cardiff, United Kingdom, and colleagues."An investigation of the site of action of apraclonidine incidentally uncovered a reversal of anisocoria in patients with absent sympathetic innervation of one pupil due to its alpha-1-effect on a pupil with denervation supersensitivity.... The easy availability of apraclonidine, its mild alpha-1-agonist activity, and its hitherto benign safety profile has encouraged its use as a first-line drug in the diagnosis of oculosympathetic paralysis."

英国加地夫市威尔斯大学附设医院的外科学硕士Patrick Watts及研究同仁指出，Apraclonidine是一种选择性的α-2-拮抗剂，是用来降低眼内压，并减少其母系药物降保适使用上的相关全身性副作用；在一项针对apraclonidine作用位置的研究中，因其单侧瞳孔神经切除之α-1-效应，而附带提出单侧瞳孔无交感神经支配患者之瞳孔大小不等为可逆转，apraclonidine之高可利用率，其轻微的α-1-拮抗活性，以及迄今良好的用药安全档案，更强化其作为视交感神经瘫痪诊断第一线药物的使用率。

Five pairs of 45S rDNA loci and two pairs of 5S rDNA signals were detected on chromosomes of Cucurbita moschata Duch. Luffa cylindrical Roem. contained five pairs of 45S rDNA loci and one pair of 5S rDNA loci. In Benincasa hispida Cogn., two pairs of 45S rDNA sites and one pair of 5S rDNA site were detected. In this species, 5S rDNA and one pair of the 45S loci were collocated closely in chromosome 7S. 45S rDNA chromosomal distribution patterns were highly conserved among the three species, althoufh their number varied markedly. The 5S rDNA sites on chromosomes among the three species were highly polymorphic.

南瓜有5对45S rDNA位点， 2对5S rDNA位点；丝瓜具有5对45S rDNA位点， 1对5S rDNA位点；冬瓜具有2对45S rDNA位点， 1对5S rDNA位点， 5S rDNA位点与其中一对45S rDNA位点都位于7号染色体短臂上，并在物理位置上紧密相邻。45S rDNA在这3种作物染色体上数目变化较大，但在染色体上都倾向分布在短臂末端，其分布模式较为一致。5S rDNA在这3种作物染色体上数目相对保守，但在染色体上分布的位置变化较大。

The result of the study shows that the morbidity of the hospital infection in 305 elderly died cases dis- eases was 33.8%, The lungs were the first major site of the infection (66.9%) and followed by urinary tract infection (19.4%), The factors of high risk in- ducing hospital infection included advanced age invasive procedures, multi-antibiotics used in com- bination and hormonotherapy.

本文结果表明，305例老年死亡病例医院感染的发病率为33.8％。感染最多部位为肺部(66.9％)，其次为尿路感染(19.4％)。高龄患者，侵袭性操作、多种抗生素联合应用，激素疗法等是诱发医院感染的危险因素。58.8％的病原菌为革兰氏阴性杆菌，37.2％为真菌。31株病原菌药敏结果显示耐药率为33.3％。

To investigate the leyels of lead, cadmium and copper in blood and urine samples among residents in an electronic waste recycling site as well as frequencies of micronucleated binucleated cells in those subjects.

［目的］研究电子垃圾拆解集散地居民血尿铅、镉、铜的暴露水平和淋巴细胞双微核率的变化及其影响因素。

In the project the good integration has been kept in mind in its urban environment and its fitness to the bioclimatic conditions of the site taking the maximum advantage by the available orientations, the materials of the region, the aesthetic composition of the architecture, as well as the in force regulation for building and installations.

在这个方案当中基地与城市肌理完美结合，气候环境与基地的相互融合，采用最好的朝向，采用当地的材料，建筑美学的体现，在规范和设施管理的引导下，这些所有的因素造就了这个建筑，这些将会深深的统一在人们的脑海当中。

In the NPC cell lines,loss of BLU expression correlated with hypermethylation of the 20 CpG sites in the 5′ region of BLU(approximately -292bp to -23bp upstream the translation start site)as revealed by bisulphite sequencing. Expression of the gene was restored aftertreatment with 5-aza-2-deoxycytidine in CNE2, suggesting that repression of BLUtranscription might at least be partially mediated by promoter methylation.

结果显示，BLU基因翻译起点ATG上游-292--23bp区间内的20个CpG位点在5例细胞系中均被完全或者部分甲基化，与基因的表达缺失呈负相关关系；去甲基化试剂5-Aza-CdR处理CNE2后基因表达部分恢复，说明甲基化至少是引起BLU基因转录抑制的部分原因。

It is inportant to understand the limitations of rock mass classification schemes（Palmstrom and Broch,2006）and that their use does notreplace some of the more elaborate design procedures.However,the use of these design procedures requires access to relatively detailed information on in situ stresses,rock mass properties and planned excavation sequence,none of which may be available at an early stage in the project.As this information becomes available,the use of the rock mass classification schemes should be updated and used in conjunction with site specfic analyses.

最重要的是理解的限制(Palmstrom岩体划分方案及Broch，2006年)，他们的使用不部分的取代更多精心设计的程序然而，使用这些设计程序需要获得相对的详细资料，对原位应力、围岩特性和计划挖掘序列中，所有这些都是极有可能在早期的工程这个信息，利用岩体的分类方案应更新，并结合现场应用光学分析。

Results The long term results of the vascularized fibular graft varied in different types of bone defects. Nine patients with congenital pseudoarthrosis of tibia had the limb function restored in 65％ and one had nonunion of fibular graft, 3 fractures(7 times), and 5 angular deformities. Three patients with congenital radial deficiency had 62％ restoration of the limb function. All of them showed early closure of epiphyses of the grafted fibulae. Five cases with osteomyelitis and bone defects combined soft tissue deficiency had 94％ restoration of the limb function, and only one occurred fracture of fibular graft. One case with soft tissue defect and concomitant ulnar defect, ulnar nerve and median nerve injury, 67％ function of limb was recovered, and union of fibula graft was good. 100％ function of limb was recovered in 1 case with cavernoma of radius and without occurring valgus deformity of donor site.

结果应用带血管腓骨移植修复骨缺损的远期效果因缺损类型的不同而存在较大差异。9例先天性胫骨假关节患者，术后肢体功能恢复65％，其中移植腓骨骨不连1例、骨折3例(7次)、成角畸形5例；3例先天性桡骨缺如患者，术后肢体功能恢复62％，3例术后均出现移植腓骨骨骺线早闭，畸形复发；5例骨髓炎、骨外露、骨缺损并软组织缺损患者，术后肢体功能恢复94％，仅1例发生移植腓骨骨折；1例前臂软组织缺损并尺骨缺损，尺神经、正中神经损伤者，术后肢体功能恢复67％，骨愈合顺利；1例桡骨海绵状血管瘤者，术后肢体功能恢复100％，骨愈合顺利。

Using HPLC separation and receptor binding assay, the present study demonstrated that the principle in the water extract of Huangqin acted on the BDZ binding site was not baicalin, wogonin or chrysin. In vivo study, WEH had no significant effect on pentylenetetrazol-induced clonic seizures in mice, although it could inhibitmaximal electroshock-induced tonic seizures with an ED50 of 3.6g/Kg.

本研究中，藉由高效率液相层析术与接受器结合实验评估，证实黄苓水抽提物中作用在BDZ结合处之主要成分，并不是黄苓甘、泛黄苓素或chtysin。

The most frequent mechanism was commissural MR, or MR that originated at the site of successful commissurotomy, which occurred in 27 of 47 patients (57%), whereas noncommissural MR occurred in 20 (43%) patients, 12 (26%) with subalular damage resulting in chordae rupture and flail motion and 8 (17%) with leaflet laceration.

最常见的机制是联合部瓣膜返流或成功的瓣膜分离术术后原分离处的返流，47例患者中有27 例出现以上情况(57%)，而其余的发生非联合处的二尖瓣返流的20例(43%)患者中，12例伴有瓣膜下损害的患者出现腱索断裂和连伽运动，8例患者出现瓣叶撕裂。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。