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Zerenex has recently completed a Phase 2 clinical program as a treatment for hyperphosphatemia in patients with end-stage renal disease, and Keryx is in the process of finalizing the U.S. Phase 3 program for Zerenex in consultation with the FDA.

Zerenex最近完成了第二期为高磷血症治疗的临床程序末期肾脏疾病，Keryx最后确定美国第三阶段的磋商，计划与FDA Zerenex过程。

In this study,we compared women in the follicular phase with low progesteronelevels and in the luteal phase with high progesterone levelsregarding their anesthetic requirements.

在该研究中，作者就黄体酮水平较低的卵泡期的妇女和黄体酮水平较高的黄体期的妇女对麻醉药物的需要量进行了比较。

The possible mechanism through which the winter AO influences winter air temperature in northeast China is that at the ground surface when the winter AO index is in a low phase,the Siberia high is strengthened,the winter monsoon over the East Asia is also strengthened,and northeast China undergoes a successive cold winter;and in the middle troposphere,when the winter AO is in its low phase,the East Asia trough is strengthened,the ridge west and north of Baikal Lake is also strengthened,the circulation develops meridionally,the northerly wind is strengthened,and northeast China undergoes successive coldwinter.

可能影响机制是：在地面，冬季北极涛动处于低指数期时，西伯利亚高压增强，亚洲大陆偏北冬季风增强，东北为持续冷冬期；在对流层中层，冬季北极涛动处于低指数期时，东亚大槽加深，贝加尔湖以西以北脊增强，环流呈经向型发展，东北对流层中层偏北风增强，东北为持续冷冬期。

The result shows that modification can make the β-Si phase thin when the joining amount is 0.3wt%, making the best modification result. Alloying elements Mn and Ni are always used to neutralize iron"s harm in aluminum alloys. They can form many kinds of complicated metallically compounds with Fe and Al, and eliminate needle-like iron-rich phases to reduce iron"s harm in Al-Fe alloy. Copper makes the alloy microstructure thick and electromagnetic stirring obviously makes the alloy microstructure thin, round the second phase, when the stirring voltage is 200V, making the best result; Reheat makes liquid phases emerge in the alloy, when the warming temperature is 650?

研究结果表明：红磷可以明显细化合金中的初晶硅，当加入量为0.3wt%时，取得最佳变质效果；锰、镍合金中加入后，通过形成多种复杂金属间化合物，细化针片状富铁相，减小铁对铝硅合金性能的危害；铜使合金微观组织发生粗化；电磁搅拌明显细化合金组织，使第二相圆整化，搅拌电压为200V时，取得最佳细化效果；二次加热使合金组织中产生部分液相，在650？

Results: Proliferation of K562 cells was significantly inhibited by naringenin and the IC50 at 24, 48 and 72h were 455, 225 and 175μmol/L respectively. Cell growth inhibition and apoptosis were observed under light microscope and transmission electron microscope. Observation by flow cytometry indicated that K562 cells were blocked in G0/G1 phase of cell cycle in naringenin group, and S phase cells were remarkably decreased. PCNA expression in each treatment group was remarkably less than in control group.

结果：柚皮素对K562细胞增殖有明显抑制作用，作用24，48和72h后的半数抑制浓度(IC50)分别为455，225和175μmol/I；柚皮素处理组细胞在普通光镜和电镜下均见观察到显著的增殖抑制和典型的细胞凋亡形态学改变；流式细胞仪分析证实柚皮素能使K562细胞聚积在G0/Gl期，S期细胞减少；在处理组PCNA的表达显著低于对照组。

In this thesis, several problems of time-dependent systems in various branches of physics are investigated by making use of the generalized invariant theory and the invariant-related unitary transformation formulation. The problems are given as follows:(1) Spin model and geometric phase factor in the fiber We investigate the fiber experiment performed by Chiao-Tomita and the Chiao-Wu theory concerning the geometric phase factor in the optical fiber, and then show that the investigation of the propagation of photons inside the noncoplanar optical fiber can be regarded as that of a second-quantization spin model.

本论文用推广的不变量理论和与不变量有关的幺正变换方法研究了一些物理分支中的几个含时系统问题：(1)自旋模型与光纤中光子几何相因子问题重新考察了Chiao-Tomita光纤实验和Chiao-Wu关于光纤中光子几何相因子的理论，证明了在非共面弯曲光纤中传播的光子运动问题实际上可以化为二次量子化含时自旋模型研究。

For the measuring algorithm of the electrical parameters, it was emphasized to discuss the measuring computation of reactive power in three-phase circuits, and the author theoretically deducted its measuring errors in both nonsinusoidal waveform circuits and three-phase unbalanced load systems in this paper.

对于电参量的测量计算，本文着重论述了三相电路无功功率的测量计算，并就三相电路非正弦不对称的情况下无功功率的测量计算进行了理论推导。

The laser-cladding layeron the alloy consists of matrix phase of over-saturation solid solution γ and complexhexagonal carbide M_7C_3. Under certain condition, with fast laser scanning speed, the oversaturation solubility of elements increases in γ, and the precipitation of the complexcarbide M_7C_3 decreases, so that the microhardness increases and the wear resistance de-creases. But at slower laser scanning speed, more complex carbide M_7C_3 may precipitate, andthe wear resistance may be improved. Therefore, it is believed that the principal factor in im-provement over wear resistance is the precipitation of carbide M_7C_3, while overmicrohardness is the over-saturation solubility of elements in matrix phase.

表明：(1)激光熔覆合金层是由过饱和的γ基体相和复杂的六方M_7C_3碳化物相所组成(2)在其他参数不变的情况下，随激光扫描速度的提高，γ基体相过饱和度增大，而析出的碳化物含量减少，因而合金层的硬度升高，耐磨性有所下降；而降低激光的扫描速度，碳化物M_7C_3析出增加，有利于提高合金层的耐磨性、因此碳化物M_7C_3析出量是提高耐磨性的主要因素，而增加基体相γ的过饱和度则是硬度提高的主要因素

In solid phase process, the polyiodides, which include triiodide, pentaiodide, heptaiodide, nonaiodide and undecaiodide tetra-n-butyl ammonium iodide, tetrabutyl ammonium bromide and tetramethyl ammonium iodide poly-compounds, were synthesized by the low-heat solid phase reaction between iodine and tetra-n-butyl ammonium iodide, tetrabutyl ammonium bromide or tetramethyl ammonium iodide; In complexation process, solution polyiodides were synthesized by complexing action of different agents; In resinifying process, triiodide, pentaiodide, heptaiodide resinic polyiodides were synthesized by ion-exchange when the strong basicity styrene anion exchange resin, potassium iodide and iodine were used as raw materials.

固相法是用正四丁基碘化铵、四丁基溴化铵或四甲基碘化铵分别与碘作用，通过低热固相反应，合成出碘三、碘五、碘七、碘九和碘十一形式的正四丁基碘化铵、四丁基溴化铵或四甲基碘化铵的系列高聚碘化合物；在络合法合成溶液高聚碘的实验中，选用几种络合剂通过络合作用首次合成了溶液高聚碘；树脂法合成高聚碘的实验是采用强碱性苯乙烯系阴离子交换树脂、碘化钾和碘为原料，通过离子交换，合成了碘三、碘五和碘七形式的树脂高聚碘。

In this paper, the concept of FGM is firstly applied in cement-based materials to study the effect of dispersion phase gradient distribution in cement-based materials on physicomechanical property and functions after the effect of dispersion phase and its mechanism in cement-bas

在没有专门的水泥基梯度材料成型设备的情况下，采用组分梯度变化，通过分层布料和机械振动成型的方法，通过合理的控制，基本上保证了组分的相对梯度变化，分层越多，梯度分布连续性越好。研究工作主要有三个方面

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。