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For normal mouse, Yi Shen Granule could prolong the swimming time of mouse, the survival in Yi Shen Granule groups was more than that in model control group in same cold condition. For low-immune mouse, The eliminated rate of carbon granule in Yi Shen Granule groups rats was faster than that in model control group rats, it showed that phagocytosis was boosted up, the absorbency of upside liquid in Yi Shen Granule groups rats was more than that in model control group rats in hemolysin mensurated test, it indicated that more antibody was come into being by giving Yi Shen Granule.

益肾颗粒可以延长小鼠游泳时间;增加在同一寒冷条件下,相同时间内小鼠的存活数;对免疫力低下小鼠,给药组动物的碳粒廓清指数增大,反映吞噬功能增强;在血清溶血素含量测定试验中,给药组动物的上清液吸收值增大,说明机体产生的抗体较多。

These three groups show the lowest willingness to pay for the fee of increasing the government's tax revenue. The groups of mass consumption and positive concernment show the highest willingness to pay fee for the use of education in ecological. The group of protecting environment shows the highest willingness to pay for the fee of interpreter's salary. The groups of protecting environment and positive concernment show the difference between the fees of ecological preservation. The groups of mass consumption and positive concernment show the difference fees of ecological education. The group of positive concernment shows the highest willingness to pay fee to the use of interpreter's salary, ecological preservation, increasing governments' tax revenue, and the use about ecological education.

研究结果发现此三集群游客均对於支付解服务费用作为增加政府税收之愿付价格为最低;「大众消费」及「热衷投入」集群均对於支付费用作为生态保育经费之愿付价格最高,「保护环境」集群则对於支付费用作为解员薪资之愿付价格最高;「保护环境」和「热衷投入」集群对於支付费用作为生态保育经费有显著性差;「大众消费」和「热衷投入」集群对於支付费用作为生态教育费用亦有显著性的差;「热衷投入」集群对於支付解服务费用作为解员之薪资、生态保育经费、政府税收和教育经费的愿付价格均是三集群中最高。

While all the phenyl groups in tetraphenylphenyl groups or benzophenanthrene groups are not coplanar. At the same time, by density function theory, the electronic energy gap between HOMO and LUMO frontier molecular orbitals of condensed aromatics are calculated and the Eg of acenaphthenyl groups in C_2 gum is the smallest, which explains the reason why C_2 gum has the best radiation protection effects.

利用甲基三氯硅烷和溴苯的格氏反应合成了甲基苯基二氯硅烷,用核磁分析证实了格氏反应中高沸点副产物为甲基二苯基氯硅烷;通过甲基苯基二氯硅烷和二甲基二氯硅烷的共水解,再裂解而制得含Me_2SiO链节的甲基苯基环硅氧烷混合物,进而利用碱胶开环聚合得到甲基苯基硅橡胶生胶;也可通过甲基苯基二氯硅烷水解所得甲基苯基环硅氧烷D_3~(3Ph、D_4~(4Ph_)与D_4开环聚合制得甲基苯基硅橡胶生胶。

Its hydrophilic groups is the inside carbonyl and amine base, and its lipophilic groups is the inside hydrocarbon chain and outer methyl. PAMAM of integral generation basically has not the surface activity. Its reason is that its outer groups is acylamino groups having very strong hydrophilicity so as not to reduce the surface tension of water. PAMAM different from traditional surfactant, have not critical micelle concentration, and exist in the form of "unimolecule micelle" in water.

结果表明:半代的PAMAM水溶液的表面活性与其分子具有两亲结构有关,亲水基团是内部的羰基和胺基,亲油基团是内部的碳氢链和外层的甲基;整代的PAMAM水溶液基本上没有表面活性,其原因是其最外层基团是酰胺基,亲水性很强,不能降低水的表面张力;树状大分子与传统的表面活性剂不同,不存在临界胶束浓度,在水中是以&单分子胶束&形式存在。

The results were as follows:(1) Seeds of 80 species or subspecies could be classified into two groups. Group Ⅰ included the seeds of Gramineae, Cyperaceae, Polygonaceae and Amaranthaceae, and Group Ⅱ included the seeds of Compositae, Euphorbiaceae, Brassicaceae and Umbelliferae.(2) Only FTIRs of the seeds of Brassicaceae were clustered together in the dendrogram,while those of the other families all appeared farraginous.(3) Among FTIRs of the 11 groups of the congeneric species,8 groups were clustered with other genus species, and 6 out of 7 groups of conspecific seeds appeared farraginous in the dendrogram.

结果表明:(1)80种草本植物的种子可以分成两类,第1类由禾本科、莎草科、蓼科和苋科植物的种子组成;第2类由菊科、大戟科、十字花科和伞形科植物的种子组成;(2)聚类图上,只有十字花科植物的种子能较好地与其他科的相区别;(3)在11组同属不同种植物中,有8组植物与亲缘关系不同的其他属的植物混在一起;在7组同种不同亚种或品种植物中,仅有1组植物被聚合在一起。

The biomechanical tests showed that two kinds of artificial bones had not significant difference on compressive strength and Young\'s modulus(P>0.05),while the flexural strength of nano-nacre artificial bone was less than the control group(P<0.05).3.The results of CCK-8 showed that the difference were not significant in each group,the proliferation of osteoblast reached the peak at the 5th day;7 days after being co-cultured,the total protein content of study group was higher than control group and blank group(P<0.05),while the difference between control group and blank group was not significantP>0.05The difference of alkaline phosphatase activities among three groups was not significant(P>0.05The SEM view showed that osteoblast attached and grew well in two kinds of artificial bone.4.X-ray photography showed that two kinds of powder started to degrade in 2 weeks;this phenomenon became more appear in 4 weeks,nano-nacre powder degraded faster than micron-nacre powder,while the hole shadow was easy to be found;in 8 weeks,all the femoral holes recovered and returned to normal bone mineral density in all groups.Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone grew fastest around the bone defect area in study group,while most slowly in blank groupP<0.05 SEM(scanning electron microscope observation showed that nano-nacre powder degraded more quickly.The same result can be found through the demineralized sections morphometric analysis,and both of the composite artificial bones made from those two kinds of nacre powder had the good connection with the adjacent tissue in rats body without apparent inflammatory response.5.X-ray photography showed that rabbit\'s bone defects healed faster in study group since NNAB implanted than in control group since MNAB implanted.At 24 weeks after operation,bone density in radial defects had nearly accessed to the normal area,while lower in control group,and turned up nonunion in blank group;The checking of BMD showed that results in study group were higher than those in control group at 8,16 and 24 week(P<0.05), and the difference between the BMD values in study group at 24 week and those in blank group was not significant(P>0.05).The gross specimens showed satisfactory histocompatibility both in study group and in control group,with bone tissue growing from two sides into the center of implanted materials; Normal slices in HE stain and hard tissue grinding slices in Stevenel\'s blue/Van Geison\'s picro-fuchsin stain showed that the bone growth tendency was better in study group than that in control group,and the medullary cavity had been penetrated to the implanted materials in study group at 24 week;Analysis of tetracycline fluorescent double marks in the hard tissue grinding slices indicated that new bone in both groups grew fastest 8 weeks after surgery,while slow down at 16 week.

纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨分别与成骨细胞共培养后,其各时间点CCK-8法检测值与空白对照无显著差异(P>0.05),成骨细胞均在第5天达到增殖高峰期;培养7天后,实验组细胞蛋白含量高于对照组及空白组(P<0.05),后两者之间则无显著差异P>0.05碱性磷酸酶活性在三组间均无显著差异(P>0.05电镜下可见成骨细胞在两种人工骨上都有良好生长贴附能力。4.X-ray显示两种粉体在大鼠股骨骨洞植入第2周时都开始出现了降解,第4周时更为明显,纳米珍珠层粉较之微米珍珠层粉降解更快,而空白对照组骨洞阴影仍可见,至8周时,则所有组骨洞均己闭合修复,X-ray下已不可见原钻孔痕迹,恢复正常骨质密度;硬组织磨片四环素荧光双标记结果显示纳米珍珠层粉植入组较其余两组在骨缺损区周围新骨生长速度更快,空白组速度最慢P<0.05电镜观察及常规脱钙切片亦可见到纳米粉体降解较快;由以上两种原材料制得的纳米珍珠层/消旋聚乳酸复合人工骨与微米珍珠层/消旋聚乳酸复合人工骨在大鼠体内均与周围组织结合良好,无明显炎症反应。5.X-ray显示纳米珍珠层/消旋聚乳酸复合人工骨植入兔桡骨缺损区后其骨愈合速度较对照组微米珍珠层/消旋聚乳酸复合人工骨植入的快,至植入术后24周,实验组骨缺损区接近正常骨密度,对照组骨缺损区密度较低,空白组则呈现骨不连状态;骨密度测量结果显示术后8周、16周、24周实验组的骨密度值高于对照组(P<0.05,24周实验组的骨密度值与术前所测得的正常值无显著性差异P>0.05动物取材大体所见均显示组织相容性良好,骨组织逐渐由植入材料两端向中央生长;常规切片HE染色及硬组织磨片Stevenel\'s blue/Van Geison\'s picro-fuchsin联合染色均可见实验组骨缺损区长势优于对照组,至术后24周,实验组骨髓腔与材料已呈相交通状;硬组织磨片荧光显微镜下观察,两组材料在术后8周处于骨生长最快速时期,16周时速度开始减慢,术后4、8、16周时实验组的新骨生长速度均较对照组的快

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

The results were as follows: ET〓-RNA expression levels in hypothalamus, hippocampus and temporoparietal grey and white matters of the low and high speed injury groups were elevated significantly than that of control group (p<0.05), but in the above areas of brain, ET〓-RNA expression in hypothalamus and hippocampus were the highest (p<0.01), especially in the high speed injury group; ET〓 contents in hypothalamus and hippocampus in the two injury groups, especially in the high speed injury group, increased very significantly than that of control group (p< 0.01); ET〓 contents in CSF and plasma in the two injury groups, also especially in high speed injury group, increased markedly after 2 hours, and lasted for 8 hours after injury; ET〓 contents in the abovt areas of brain were of highly positive correlation with that in plasma or in CSF.

实验显示:致伤犬伤后海马、丘脑下部、颞顶叶灰、白质内皮素—1RNA表达较对照组显著增强(p<0.01,p<0.05),其中以海马和丘脑下部最显著(p<0.01),高速组最明显(p<0.01);海马和丘脑下部ET〓含量较对照组显著升高(p<0.01);血浆、CSF中ET〓含量在伤后2h即极显著升高(p<0.01),并持续至伤后8h,上述各组均以高速组最为显著(p<0.01);各脑区和血浆,CSF中ET〓含量间呈显著正相关。

Result: compared with the placebo groups, there were significant differences in the improvement of fev1 (forced expiratory volume in one second) of nebulized budesonide and oral prednisolone groups than placebo group, but there were no significant differences between of nebulized budesonide groups and oral prednisolone groups.

结果:布地奈德雾化和口服泼尼松龙组第一秒末最大呼气流量(fev1)和动脉血气的改善程度明显优于安慰剂组,而布地奈德雾化组和口服泼尼松龙组间差异无统计学意义。

In experiment one, male weanling Wistar rats were divided into 13 groups after being anemic; in hemoglobin repletion period, 5 groups were fed on standard diets (FeSO4 provided 0ppm, 6ppm, 12ppm, 18ppm and 35ppm of Fe), 3 groups were fed on milk A diets (milk A provided 6ppm, 12ppm, and 18ppm of Fe), 4 groups were pair-fed on milk A (daily supply of 2g, 3g, 4g and 6g of milk A powder), and one group was pair-fed on milk B (daily supply of 3g of milk B powder). The hemoglobin regeneration efficiency of milk A (19%-29%) was significantly lower than that of FeSO4 (69%-90%) and that of milk B (79%).

实验一采用雄性离乳Wistar大鼠,经耗铁贫血后,分为十三组,分别饲以标准饲料(以FeSO4供铁0ppm,6ppm,12ppm,18ppm,35ppm);奶粉饲料(以奶粉A提供铁6ppm,12ppm,18ppm);奶粉A对饲育组(每天供应2g,3g,4g,6g奶粉A);和奶粉B对饲育组(每天供应3公克奶粉B);两周的血红素再生期后,奶粉A与其对饲育组的血红素再生率(19%~29%)显著低於标准饲料(69%~90%)和奶粉B(79%)。

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