查询词典 in excess of
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The present invention relates to a process for rapid solution synthesis of a peptide, the process comprising repetitive cycles of steps-: a coupling step, using an excess of an activated carboxylic component to acylate an amino component, a quenching step in which a scavenger is used to remove residual activated carboxylic functions, wherein the scavenger may also be used for deprotection of the growing peptide, one or more aqueous extractions and optionally, a separate deprotection step, followed by one or more aqueous extractions, characterised in that the process comprises at least one step, referred to as step, in which an amine or a thiol comprising a free anion or a latent anion is used as a scavenger of residual activated carboxylic functions.
本发明涉及快速溶液合成肽的方法,该方法包括步骤-的重复循环:偶联步骤,使用过量的活化羧基成分酰化氨基成分,淬灭步骤,在该步骤中使用清除剂除去残余的活化羧基官能团,其中该清除剂还可以用于使生长中的肽去保护,一或多个水抽提和任选地,独立的去保护步骤,之后进行一或多次水抽提,其特征在于该方法包括至少一个步骤,称作步骤,在该步骤中包含自由阴离子或潜阴离子的胺或硫醇用作残余活化羧基官能团的清除剂。
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Those in whom the faculty of approximation to the beautiful exists in excess are poets, in the most universal sense of the word.
审美力最充沛的人,便是从最广义来说的诗人。
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America can therefore in the development of new energy technology, trade in excess profit, in order to earn $out of circulation.
美国因此可以在新能源技术的开发、交易中获得超额利润,以此来赚回流转出去的美元。
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On one hand, freedom and individuality in romanticism developed in excess early in the 20th century and clashed with the demands of times and Eliot's opinion. On the other hand, religion became aesthetics taste and God became unreligious in romanticists, but Eliot insisted on rebuilding God and Christianity to save the world and times.
一方面浪漫主义创作特征中固有的"自由"与"个人化"在二十世纪初推向情感滥觞的极致而为时代需要和艾略特主张所摒弃;另一方面,浪漫主义者所具有的个体宗教感受与对"上帝"的审美化认识使得宗教不再具有权威性和神圣性,这必然与世纪初因缺乏宗教信仰而急需重建信仰的西方世界,与艾略特希望通过重构基督教信仰以拯救西方世界形成冲突,而这无疑也是一种"个性化"与"非个性化"之间的对立。
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This subset is hyporesponsive and anergic to antigen stimulation. Recently, it has been demonstrated to participate in the immune deficiency in human immunodeficiency virus infection and has close relationship with the development of acquired immunodeficiency syndrome. Meanwhile, the CD4(superscript +)D25(superscript +)Treg is also infected when the human body is invaded by HIV. The CD4(superscript +)CD25(superscript +)Treg will finally be killed by the mechanism of antibody-dependent cell-mediated cytotoxicity. Because of the decrease of the CD4(superscript +)CD25(superscript +)Treg, it can't function as a immune suppressor as a result of the excess of activation of HIV and gradually exhausting of the T cell, which shows that the CD4(superscript +)CD25(superscript +)Treg plays a inhibitory role in the different stages of the development of the HIV as well as different effects in the pathogenesis of AIDS.
它能够抑制自身免疫病的发生和发展,参与肿瘤免疫的调节,同时在感染和移植免疫中也发挥着极其重要的作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性,新近发现它亦与爱滋病的发生、发展关系密切HIV进入人体后,CD4D25调节性T细胞抑制了机体的免疫效应但它也同时被感染,最终由于细胞毒的作用而死亡由于调节性T细胞数量的减少不能有效的发挥其抑制作用,HIV持续的过度活化使得T细胞逐渐耗竭说明在HIV发生、发展的不同阶段Treg细胞可能都发挥了免疫抑制作用,但是却对HIV感染与爱滋病发病的进程产生了不同的效应。
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The third part of this thesis is reactive simulating calculation In this section, some well-known auxiliaries are selected to compute in density functional theory B3LYP on Gaussian 03, from which the relationship between reaction active energies of transition states and enantiomeric excess of chiral products homoallylic alcohols isobtained based on relative reactive ratio theory. Using this relationship, calculations on the reaction of more than eight auxiliaries with four other aldehydes are carried out in AMI and MNDO, proving that N,N\'-dibenzyl tartamide has higher enantioselectivity than others in this reaction.
第三部分为计算化学部分,运用密度泛函理论B3LYP方法在Gaussian03软件上对已经报道的几种手性配体参与的醛不对称烯丙基化反应过程进行模拟计算,基于相对反应速率理论找出两种构型过渡态间活化能的差异与产物光学收率之间的关系;并以此为基础,用AM1和MNDO方法对上述合成的几种配体控制的反应过程进行量化计算,从而在理论上证实了N-苄基酒石酸二酰胺配体在醛的不对称烯丙基化反应中具有较高的立体选择性。
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Methods and results LVH was assessed by echocardiographic LV mass index in g/m(2.7 and excess of LV mass (eLVM, in % of the observed value) relative to the amount predicted by sex, stroke work, and height, using a prognostically validated equation in 2078 participants of Cardiovascular Health Study without prevalent MI and normal systolic function.
方法和结果:通过超声心动图左心室质量指数(g/m(2.7))和左心室剩余质量测定LVH,两者均与性别,心脏搏功,身高因素有关。
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One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.
胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,&PMN-EC&相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。
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It is a strange thing, to note the excess of this passion, and how it braves the nature, and value of things, by this; that the speaking in a perpetual hyperbole, is comely in nothing but in love.
Version 1:奇怪的是,过度的爱情追求,必然会降低人本身的价值。长期的夸张的言辞惟有在恋爱的中是合适的,在其他的事情中总是不宜。
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That influential artists 2, age is still hours 3, Please give my greetings to your parents 1, his parents made him very happy things 2, a lot of houses have been built to meet the needs of the people 3, Lincoln is considered one of America's greatest president 4, in the prompt at any time, he has published two novels of the 5, to his 18-year-old, I believe that he was the university examinations into the 6, and sometimes it is hard to refuse the invitation of a friend 7, can turn the radio tube smaller 8, many students shut themselves up in a room to learn 9, most of them have experienced the Second World War 10, many people patronize the Carnival 11, the number of students in this school the school in excess 12, I can not help but laugh with them 13, to hear the exciting news, I could not help but jumped up happy 14, who, as a wise leader will be remembered 15, this book belongs to you do 16, master a foreign language is very difficult to 17, I lived in a remote house, but it does not feel lonely 18, can you imagine JOHN do like fishing in the river 19, he was very hard to learn.
问题补充:后面的 1、他父母对他所作的事情很满意 2、已经建造了好多房子来满足人民的需要 3、林肯被认为是美国最伟大的总统之一 4、在提示随时,他已经出版了两本小说了 5、到他十八岁时,我相信他会考进那所大学 6、有时拒绝朋友的邀请真的很难 7、能不能把收音机管小一点 8、许多学生把自己关在房间里学习 9、他们中的大多数人经历过第二次世界大战 10、许多人光顾了嘉年华 11、这所学校的学生数多余那所学校 12、我忍不住和他们一起笑了 13、听到这令人兴奋的消息,我忍不住开心的跳了起来 14、他作为一位睿智的领导人将被永远铭记 15、这本书属于你吗 16、掌握一门外语是很难的 17、我一人住在偏僻的房子里,但并不感到孤单 18、你能想像JOHN在河边钓鱼的样子吗 19、他很努力学习。
- 推荐网络例句
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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.
索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。
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The relationship between communicative competence and grammar teaching should be that of the ends and the means.
交际能力和语法的关系应该是目标与途径的关系。
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This is not paper type of business,it's people business,with such huge money involved.
这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。