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Sleep apnea syndrome is regarded as the most important sleep disorder discovered in the 20th century as well as the significant research direction for sleep medicine. Sleeping breath-ceasing results in a symptom of repeated arterial anoxemia in sleeping, which can easily cause harm to cardio- pulmonary and causes sequela and complicating disease such as excessive day-time sleepiness and drowsy driving, even sudden death in sleeping. In such situations, the disease not only consume a lot of medical resources but also has a bad impact on the patient' living quality.

睡眠呼吸中止症候群被认为是二十世纪所发现最重要的睡眠障碍,也是睡眠医学重要的研究方向,患者因睡眠呼吸中止造成睡眠期间反覆缺氧的结果而容易导致心肺功能受损、白天嗜睡、疲劳驾驶等并发症与后遗症,严重者甚至造成睡眠中猝死,不但耗费医疗资源,也将严重影响患者生活品质。

It was in the cities that the elements that can be associated with modern capitalism first appeared--the use of money and commercial paper in place of barter, open competition in place of social deference and hierarchy, with an attendant rise in social disorder, and the appearance of factories using coal or water power in place of independent craftspeople working with hand tools.

正是在城市中首先出现了能够与现代资本主义相关联的因素—货币和商业票据的使用代替了实物交易;开放的竞争代替了社会顺从和等级制度,而随之而来的是社会秩序的紊乱;出现了以煤和水为动力的工厂,取代了利用手工工具的独立手工业者。

It was in the cities that the elements that can be associated with modern capitalism first appeared – the use of money and commercial paper in place of barter, open competition in place of social deference and hierarchy, with an attendant rise in social disorder, and the appearance of factories using coal or water power in place of independent craftspeople working with hand tools.

城市中,和现代资本主义关联的因素首先出现,他们是钱和贸易纸币的使用代替物物交换、伴随着一个社会混乱的上升,开放的竞争代替社会顺从和阶级、使用煤和水能源的工厂出现代替独立的手工艺人的手工工作。

We reviewed all skin lesions in all HIV patients diagnosed in our department between 1990 and 1998 to document the spectrum of skin manifestations, the frequency of each disorder, and their relationship with CD4 counts. A total of 64 HIV patients were studied, including 38 with acquired immunodeficiency syndrome CD4 200 x 10(6 cells/L and 26 who had not developed AIDS. There were 142 episodes of skin conditions representing 25 different skin diseases, including oral candidiasis (15% in non-AIDS vs 71% in AIDS patients), drug eruptions, herpes simplex, seborrheic dermatitis, dermatophytosis, herpes zoster, secondary syphilis, condyloma acuminatum, Kaposi's sarcoma (16% among AIDS patients), hairy leukoplakia, and molluscum contagiosum (13% among AIDS patients), in decreasing order.

我们回顾自 1990 年到 1998 年人类免疫不全病毒感染患者在本院皮肤科的诊断,归纳整理各种皮肤疾病发生的机率及与 CD4 数值间的关系。64 位人类免疫不全病毒感染患者,包括 38 位爱滋病患者(CD4 200 x 10(6) cells/L)及 26 位非爱滋病患者,共有 142 种皮肤症状,分属於 25 种不同种类的皮肤疾病,依发生率的高低,包括口腔的白色念珠菌感染(非爱滋病患者:15%;爱滋病患者:71%)、药物疹、单纯疹、脂漏性皮肤炎、皮癣菌感染、带状疱疹、二期梅毒、尖圭湿疣、卡波西氏肉瘤(爱滋病患者:16%)、毛状黏膜白斑、传染性软疣(爱滋病患者:13%);并针对较特殊的病例做一介绍,如疣状的单纯疱疹病毒感染、临床表现像尖圭湿疣的传染性软疣感染及与爱滋病相关的色素性红皮症。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide,又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物,主要成分是倍半萜烯内酯,西方国家较为常用,主要用于治疗皮肤感染、风湿病和偏头痛,但近年来发现小白菊内酯能调控细胞内多种信号途径,如抑制巨噬细胞中脂多糖诱导的Cox,肿瘤坏死因子α和白细胞介素-1的表达,能抑制人单核细胞中iNOS的表达,能抑制Hela细胞中NF-κB的活性,抑制肿瘤细胞的生长,同时能减轻心肌缺血再灌注损伤等,但小白菊内酯在VSMC中的干预研究目前国内外非常罕见,为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制,我们进行了一些研究。

Osb. were stored in ultra low oxygen condition (0.3% O 2 + 0.0 %CO 2) at 5 ℃ and in normal air condition at 5 ℃ and 10 ℃ to investigate the contents of volatile compounds in fruit tissue, in order to evaluate the fruit quality and physiological disorder in ultra low oxygen atmosphere storage.

Osb 。果实在短期超低氧贮藏条件下,果皮和果汁中乙醇和乙醛等挥发性物质的含量,以及它们在不同贮藏温度和货架存放期间的变化和对果实风味品质的影响。

objective to study the correlation among psychosomatic health factors,depression,anxiety and sleep status in college students,to analyze influence factors in sleep status.methods with questionnaire opened in-vestigation,200college students were evaluated using cornell medical index,self-rating depression,self-rating anxiety scaleand pittsburgh sleep quality index.stepwise regression analysis was used.re-sults total score of sds was35.55±7.8,and sas was0.48±0.9.each score of cmi was higher than normal range,the highest was digestion system,next was respiration system,then,fatigue,eyes and ears,anxiety,sensitivity,tension,maladjustment in turn.total average score of psqi was6.32±3.6,ordinary sleep were115cases(57.5%),good and bad sleep were42(21%)and43(21.5%)cases respectively.influence factors in total score of psqi were sas,cmi,respiration system,anxiety,past healthy,digestion system,fatigue,sensitivity,sds and malad-justment in turn,using stepwise regression analysis,total score of psqi as dependent variable,each factor score of cmi,total score of sds and sas as independent variables.conclusion problems of psychosomatic health,anxiety and depression could both lead to sleep disorder.

目的 研究在校大学生心身健康因素及抑郁焦虑等与睡眠状况的相关性,并对影响睡眠状况的有关因素进行分析。方法采用问卷式的开放性研究,对在校的200名大学生进行康奈尔心身健康问卷、自评抑郁量表、焦虑自评量表和匹兹堡睡眠质量量表的测定,采用逐步回归分析方法。结果 sds总分为35.55±7.8、sas总分为0.48±0.9,cmi评分:消化系统最为严重评分为2.52,其次为呼吸系统、疲劳感、眼和耳、焦虑、敏感、紧张、不适应等,评分均高于正常常模。psqi总均分为6.32±3.6,一般睡眠有115例占57.5%,睡眠质量较好42例占21.0%,睡眠质量较差43例占21.5%。评估对睡眠状况的影响程度,以psqi总分为因变量,选择cmi各因子分和sds、sas总分作为自变量,进行多因素逐步回归分析,进入方程的因素依据标准化偏回归系数,影响psqi总分的因素依次为sas总分、cmi总分、呼吸系统、焦虑、既往健康、消化系统、疲劳感、敏感、sds总分、不适应(f=226.8;p.01;r=0.73)。结论心身健康问题和焦虑抑郁可导致睡眠障碍。

Results: 1. The depression patients in neuroendocrine abnormity make up 59.4% of the total. 2. Correlation of clinical features and neuroendocrine diversity of depression patients.① Agitate symptom often existed in HPA axle abnormal group.② The weight diversity was not obvious suffered HPT axle abnormal depression frequently, Sleep disorder and anxiety often exist in HPT axle abnormal group.③ Elder women suffered HPG axle abnormal depression frequently, The symptom of somatic often exist in HPG axle abnormal group.④ Self-reproach and delay symptom often existed in the HPA axle and HPT axle abnormal group.⑤ The adolescent fuffered the normal neuroendocrine group, Patients of the normal neuroendocrine group were often combined with anhedonia.

结果显示:⒈抑郁症患者神经内分泌异常率达到 59.4%;⒉抑郁症患者临床特征与不同神经内分泌轴具有相关性以下几点值得注意;① HPA 轴异常组抑郁症患者多伴有激越症状;② HPT 轴异常组抑郁症患者体重改变不明显,多伴有睡眠障碍、迟纯症状和焦虑症状,常出现自杀观念;③ HPG 轴异常组抑郁症患者多发于年龄偏大的女性,躯体症状多明显;④ HPA 轴和 HPT 轴均异常组抑郁症患者多伴有体重减轻和明显自责和迟滞症状;⑤正常组抑郁症患者多发于青少年,快感缺失症状明显。

Diabetes insipidus, serum electrolyte disorder and body temperature disorder took place in 16 cases,12 cases, and 6 cases respectively.

经过处理后,电解质紊乱和体温失衡完全纠正,13例尿崩症痊愈,3例得到了缓解。

There are examples where the name of the first patient or family to be described with a disease has become associated with the disorder, Christmas disease is one such disorder, indeed on occasion only the patient's initials are used—as in the naming of the JC virus.

有例子,在那里需要被由於一种疾病描述的第一个病患或者家庭的名字已经变得与紊乱相关,耶诞节疾病是一这样的紊乱,有时的确只有病患姓名的大写首字母是以JC病毒的名义useds。

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Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了

The enrich the peopling of Deng Xiaoping of century great person thought, it is the main component in system of theory of Deng Xiaoping economy, it is a when our country economy builds basic task important facet.

世纪伟人邓小平的富民思想,是邓小平经济理论体系中的重要组成部分,是我国经济建设根本任务的一个重要方面。