查询词典 in course of time

Of course, this is Favicon not just is all, according to the browser different, favicon shows also distinguish somewhat: Above version is reached like FireFox and Internet Explorer (5.5 in most mainstream browser) in, favicon shows in the favorite not only, still can appear on address column at the same time, at this moment the user is OK daggle Favicon arrives with building to the desktop the quick way; of the website besides, label type browser still has many patulous functions even, if FireFox supports the Favicon of animation format even,wait.

当然，这不仅仅是Favicon的全部，根据浏览器的不同，Favicon显示也有所区别：在大多数主流浏览器如FireFox和Internet Explorer (5.5及以上版本)中，favicon不仅在收藏夹中显示，还会同时出现在地址栏上，这时用户可以拖曳favicon到桌面以建立到网站的快捷方式；除此之外，标签式浏览器甚至还有不少扩展的功能，如FireFox甚至支持动画格式的favicon等。

As an immunomodulator NO may play a role like a double-edged sword since it expresses both in immuonchalleged and immunosspresed states. 2. After received external stimulus the morphology of ependyma of SFO could be changed and varied with time course, particularly its cellular apoptosis do occur and earlier than the ordinary areas of the brain. 3. Astrocytes in SFO could express cFos protein induced by LPS, suggesting the cells may maintain homeostasis in the brain in a longer period and modulate immune state of the brain. 4. As a CVO, SFO may sense changes of blood-bearing immunosignals earlier and instantly response to them, thus as one of windows of the brain SFO do take part in immunomodulation within the brain.

通过我们的实验结果我们可以得出这样一些初步的结论：1、一氧化氮作为免疫调质参与了机体免疫，它既能在免疫激发状态下又可在免疫抑制状态下进行表达提示，NO在脑内免疫调节中的作用可能是双向的。2、穹窿下器的室管膜形态在接受外界刺激后，随着时间的变化而不同，扫描电镜下的凋亡形态虽需进一步证实，但室管膜细胞确实发生了凋亡，并且穹窿下器发生的较早。3、穹窿下器内的星形胶质细胞在给予大肠杆菌后确实可以表达c-fos蛋白，并可能通过自身的激活来较长时间的维持体液的动态平衡，调节脑内免疫状态。4、穹窿下器作为感受性室周器官之一，能够较早的感受血携免疫信息的改变并及时作出反应，可能作为外周免疫信息进入脑内的窗口之一来参与脑的免疫调节。

Results We obtained a lysogenic bacteriophage MZTP01with clear plaque and 1 mm diameter. Fragment D with 2362bp (Genebank No. AY639599) was obtained after the phage DNA hydrolyzed by HindⅢ/EcoRⅠ. Among fragment D, the pep gene with molecular weight of 47 kDa and length of 1101bp was cloned and expressed. Recombinant M15 (pQE30pep) was built and overexpressed in Escherichia coli with a 47kDa clear band. At the same place a clear band was observed by Western blot. Judging from the time course expression, we could conclude that PEP protein produced at 1 hour after induction and then increased gradually. PEP protein was mainly in the form of inclusion body in the recombinant and slowed the growth speed of host. Homologous comparison of PEP protein from phage MZTP01 with other PEPs from BLAST were that phage MZTP01 PEP protein had 100% homologe with that of Escherichia coli K12, and most of others took the similarity in the range between 37%~84%.

诱导获得的溶原性噬菌体MZTP01斑点清晰，直径约1mm，成斑时间12h；从噬菌体基因组DNA双酶切(HindⅢ/EcoRⅠ)片段中回收长度为2362bp的D片段(Genbank登录号： AY639599)，又从D片段中克隆了长度为1101bp、编码367aa、分子量为47kDa的pep基因，表达载体M15(pQE30pep)在大肠杆菌(Escherichia coli， E.coli)中表达获得了47kDa的清晰表达带，在1h 时开始产生蛋白并有逐步上升的趋势； Western blot 也在47kDa处得到一条清晰的条带；可溶性分析表明PEP蛋白在重组菌株中是以不可溶的包含体形式存在的，该蛋白的产生明显地抑制了宿主的生长速度；噬菌体PEP氨基酸序列之间的同源性比较表明，噬菌体MZTP01 PEP蛋白与来自E.coli K12噬菌体的PEP蛋白的同源性程度最大。

This conclusion is based on three groups of experiments with detached root tips of wheat seedlings: By following the time course changes of NO synthase , superoxide synthase and ABA accumulation under dehydration stress, we found that ABA accumulation was preceeded by the changes of NOS and superoxide synthase. ABA accumulation induced by dehydtrion stress and osmotic stress can be blocked by NO scanvegers and NOS inhibitors, while only dehydration stress-induced ABA accumulation can be blocked by ROS scanvegers. Exogenous applied NO or ROS induced ABA accumulation in root tips of wheat seedlings, and synergistic effects were found between NO and NO. The in planta expereiments also proved that ROS and NO are involved in water stress-induced ABA accumulation.Ⅱ.

证据主要来自以离体根尖为材料的实验：(1)通过检测干旱胁迫下小麦根尖NOS活性、O〓合成酶活性和ABA积累的时间变化进程，发现ABA积累滞后于ROS和NO的变化；(2)抑制剂实验表明，NO清除剂和NOS抑制剂可以抑制自然干旱胁迫及渗透胁迫诱导的小麦根尖ABA积累，ROS清除剂抑制自然干旱胁迫诱导的ABA积累而不抑制渗透胁迫诱导的小麦根尖ABA积累；(3)在非胁迫条件下施加外源的ROS或NO可以诱导小麦根尖积累ABA，ROS和NO之间具有协同作用。

Textbook is not only the primary basis for students to grasp knowledge and method but also resort and carrier to train capability. New textbook has been tested in some provinces and cities since 1997, some educational and teaching concepts in new textbook inosculates with new mathematics course which is being tested now, it has taken great role for the transition of teachers' teaching idea and students' learning way. This paper will analyze Plane Analytic Geometry high school textbook of 2004 edition which is published by People's Education Publishing House in some aspects such as content structure, educational function, psychological characteristic according with student cognizance and teaching through the method of content analysis, investigation, comparison and statistical analysis . The paper's purpose is to excavate the potential value of the textbook and understand educational idea and concept of new textbook so that students can grasp more basic thought of analytic geometry in teaching and can learn studying and discovering and solving problem ,at the same time it builds a kind of independent, disquisitive, cooperative and lifelong learning pattern.

教材既是学生掌握知识和方法的主要依据，又是培养学生能力的凭借和载体，自1997年新教材在部分省市实验以来，新教材中所体现的一些教育教学理念与现在正在实验的高中数学新课程相吻合，对教师的教学观念和学生的学习方式的转变都起到了很大的作用，本文将对人民教育出版社2004版普通高中教材中的平面解析几何部分通过内容分析法、调查研究、比较研究、统计分析等研究方法从教材的内容结构、教育功能、符合学生认知心理特点、教学等几个方面进行分析，目的是挖掘教材内容的潜在价值，真正领会新教材所蕴涵的教育思想和理念，以使教师在教学中能够让学生更多的掌握解析几何的基本思想，以培养学生学会学习、学会发现问题和解决问题，为学生构建一种自主的、探究的、合作的、终身的学习模式。

Yeah but he loves you girl and you better know it We're all we got in this world When it spins, when it swirls When it whirls, when it twirls Two little beautiful girls Lookin' puzzled, in a daze I know it's confusing you Daddy's always on the move, mamma's always on the news I try to keep you sheltered from it but somehow it seems The harder that I try to do that, the more it backfires on me All the things growing up as daddy that he had to see Daddy don't want you to see but you see just as much as he did We did not plan it to be this way, your mother and me But things have got so bad between us I don't see us ever being together ever again Like we used to be when we was teenagers But then of course everything always happens for a reason I guess it was never meant to be But it's just something we have no control over and that's what destiny is But no more worries, rest your head and go to sleep Maybe one day we'll wake up and this will all just be a dream Now hush little baby, don't you cry Everything's gonna be alright Stiffen that upper lip up little lady, i told ya Daddy's here to hold ya through the night I know mommy's not here right now and we don't know why We feel how we feel inside It may seem a little crazy, pretty baby But i promise momma's gon' be alright It's funny I remember back one year when daddy had no money Mommy wrapped the Christmas presents up And stuck 'em under the tree and said some of 'em were from me Cuz daddy couldn't buy 'em I'll never forget that Christmas I sat up the whole night crying Cuz daddy felt like a bum, see daddy had a job But his job was to keep the food on the table for you and mom And at the time every house that we lived in Either kept getting broke into and robbed Or shot up on the block and your mom was saving money for you in a jar Tryna start a piggy bank for you so you could go to college Almost had a thousand dollars till someone broke in and stole it And I know it hurt so bad it broke your momma's heart And it seemed like everything was just startin' to fall apart Mom and dad was arguin' a lot so momma moved back On the Chalmers in the flat one bedroom apartment And dad moved back to the other side of 8 Mile on Novara And that's when daddy went to California with his CD and met Dr.

是的，可是他是爱你的，你应该知道在这世界上，我们拥有的只有我们自己的灵魂当它旋转，当它环绕当它周转，当它萦绕两个可爱美丽的小女孩看上去很困惑，很迷茫我知道它扰乱了你们的心智爸爸总徘徊在流浪的旅途中，妈妈总出现在时髦的新闻上我尝试着把你荫庇在我的保护中，可是不知道为什么我越是竭尽全力，越是事与愿违他的爸爸亲身经历的那些苦痛使他成长起来爸爸不愿你再承受，但是你亲历的却和他一样坎坷我们并不想为你设计如此前途的，我和你妈妈都不想但是事情却无情的在我们之间导演得这么糟糕我再也寻不回曾经共享天伦的美妙时光了就象我和她曾经的豆蔻年华但是所有的错误的发生全只在一个原因我想，这个错误从未打算被修正有些东西是我们自己无法去操控的，这便是命运的定义还是别难过了，放松你的神经去好好睡一觉罢也许某天当我们苏醒时，发现昨天的苦闷不过只是一场梦{CHORUS}好罢，小女孩，安静下来罢。你还在流泪？

Yeah but he loves you girl and you better know it We're all we got in this world When it spins, when it swirls When it whirls, when it twirls Two little beautiful girls Lookin' puzzled, in a daze I know it's confusing you Daddy's always on the move, mamma's always on the news I try to keep you sheltered from it but somehow it seems The harder that I try to do that, the more it backfires on me All the things growing up his daddy that he had to see Daddy don't want you to see but you see just as much as he did We did not plan it to be this way, your mother and me But things have gotten so bad between us I don't see us ever being together ever again Like we used to be when we was teenagers But then of course everything always happens for a reason I guess it was never meant to be But it's just something we have no control over and that's what destiny is But no more worries, rest your head and go to sleep Maybe one day we'll wake up and this will all just be a dream Now hush little baby, don't you cry Everything's gonna be alright Stiffen that upperlip up little lady, i told ya Daddy's here to hold ya through the night I know mommy's not here right now and we don't know why We feel how we feel inside It may seem a little crazy, pretty baby But i promise momma's gon' be alright It's funny I remember back one year when daddy had no money Mommy wrapped the Christmas presents up And stuck 'em under the tree and said some of 'em were from me Cuz daddy couldn't buy 'em I'll never forget that Christmas I sat up the whole night crying Cuz daddy felt like a bum, see daddy had a job But his job was to keep the food on the table for you and mom And at the time every house that we lived in Either kept getting broke into and robbed Or shot up on the block and your mom was saving money for you in a jar Tryna start a piggy bank for you so you could go to college Almost had a thousand dollars till someone broke in and stole it And I know it hurt so bad it broke your momma's heart And it seemed like everything was just startin' to fall apart Mom and dad was arguin' a lot so momma moved back On the Chalmers in the flat one bedroom apartment And dad moved back to the other side of 8 Mile on Novara And that's when daddy went to California with his CD and met Dr.

是的，可是他是爱你的，你应该知道在这世界上，我们拥有的只有我们自己的灵魂当它旋转，当它环绕当它周转，当它萦绕两个可爱美丽的小女孩看上去很困惑，很迷茫我知道它扰乱了你们的心智爸爸总徘徊在流浪的旅途中，妈妈总出现在时髦的新闻上我尝试着把你荫庇在我的保护中，可是不知道为什么我越是竭尽全力，越是事与愿违他的爸爸亲身经历的那些苦痛使他成长起来爸爸不愿你再承受，但是你亲历的却和他一样坎坷我们并不想为你设计如此前途的，我和你妈妈都不想但是事情却无情的在我们之间导演得这么糟糕我再也寻不回曾经共享天伦的美妙时光了就象我和她曾经的豆蔻年华但是所有的错误的发生全只在一个原因我想，这个错误从未打算被修正有些东西是我们自己无法去操控的，这便是命运的定义还是别难过了，放松你的神经去好好睡一觉罢也许某天当我们苏醒时，发现昨天的苦闷不过只是一场梦{CHORUS}好罢，小女孩，安静下来罢。你还在流泪？未来的一切总会好转的紧紧咬住你的唇，小女士，我告诉过你了爸爸就在身边，用双手圈住你，熬过这寂寥长夜我知道妈妈现在已经莫名其妙的远走高飞我们能触摸自己的心房有一点歇斯底里，亲爱的宝贝但我向你许诺，妈妈现在还好好的呢真搞笑我至今仍能清楚的记得有一年爸爸身无分文，不名一钱妈妈把圣诞礼物包裹好小心翼翼地挂在圣诞树上并且说，有些是你爸爸为你准备的就因为爸爸买不起他们啊！

Had the Stern of the Ship been fix'd, and the Forepart broken off, I am perswaded I might have made a good Voyage; for by what I found in these two Chests, I had room to suppose, the Ship had a great deal of Wealth on board; and if I may guess by the Course she steer'd, she must have been bound from the Buenos Ayres, or the Rio de la Plata, in the South Part of America, beyond the Brasils, to the Havana, in the Gulph of Mexico, and so perhaps to Spain: She had no doubt a great Treasure in her; but of no use at that time to any body; and what became of the rest of her People, I then knew not.

从两只箱子里找出来的东西看，我完全可以断定，船上装的财富十分可贵。从该船所走的航线来看，我也不难猜想它是从南美巴西南部的布宜诺斯艾利斯或拉普拉塔河口出发的，准备开往墨西哥湾的哈瓦那，然后也许再从那儿驶向西班牙。所以，船上无疑满载金银财宝，可是这些财富目前对任何人都毫无用处。至于船上的人究竟发生了什么情况，我当然无从得知了。除了那两只箱子，我还找到了一小桶酒，约有二十加仑。

Had the Stern of the Ship been fix'd, and the Forepart broken off, I am perswaded I might have made a good Voyage; for by what I found in these two Chests, I had room to suppose, the Ship had a great deal of Wealth on board; and if I may guess by the Course she steer'd, she must have been bound from the Buenos Ayres, or the Rio de la Plata, in the South Part of America, beyond the Brasils, to the Havana, in the Gulph of Mexico, and so perhaps to Spain: She had no doubt a great Treasure in her; but of no use at that time to any body; and what became of the rest of her People, I then knew not.

经过观察，我大受鼓舞，决定第二天早晨乘第一次潮汐出发。我把水手值夜的大衣盖在身上，在独木舟里过了一夜。第二天一早，我就驾舟出发了。最初，我一出海就朝正北驶去，走没多远，就进入了那股向东流动的急流；小舟在急流中向前飞驶，可是流速没有上回岛南边那股急流那么大，所以我尚能掌握住小舟。我以桨代舵，使劲掌握航向，朝那失事的大船飞驶过去。不到两小时，我就到了破船跟前。

This article starts with a review of the history of the "Expression" conception in the Occident literature tradition,from which to conclude the base connotation of modern "Expression" conception in occident.Relying on this springboard,we analyses the history of the occidental modern plastic arts gradually ,then the naissance and development of the occidental modern plastic arts may boil down to a going-deep course driven by the "Expression" conception:the impressionism which had been pursuing sensual reality brought out a turning point from Representation to expression;Faurism accomplished the consciousness of Expression based on inheriting and criticizing Post-Impressionisme, and resisted the suppressant on Expression by Physical Image; the German Expressionism and Surrealism uplifted Expression at the same time they resisted Physical Image by "Nugatory Physical image"; From the apocalypse of Cubism,Suprematism and De Stijl tended towards Pure Plastic which excluded Physical Image completely,meaning that it had realized absolute Expression in the range of plastic;After WW II,artsists in western detected that Pure Plastic had actually suppressed Expression newly,as a result of Abstract-Expressionism and Mirnirnaliam Art,Expression broke away from Pure Plastic gradually to seek some new possibilities other than plastic.

本文从对西方文艺传统中的&表现&观念的历史考察着手，归纳出西方现代&表现&观念的核心内涵，以此为基点来逐步分析西方现代造型艺术史，进而将西方现代造型艺术的产生与发展归结为在&表现&观念驱动下不断递进的历史进程：印象主义对感觉真实的追求为造型艺术由再现走向表现打开了缺口；野兽派在继承和批判后印象主义的基础上首次实现了表现的自觉，并在艺术中反抗物象对表现的压迫；德国表现主义与超现实主义以不彻底的&否定性物象&来张扬表现反抗物象；至上主义、风格派等则在立体主义的启示下走向完全排斥物象的纯粹造型，在造型的范围内实现彻底的表现；二战后的西方艺术家们察觉到纯粹造型已经掉转头来形成新的对表现的压制；经由抽象表现主义、最低限艺术，表现逐步摆脱了纯粹造型，寻求造型之外的新的表现可能。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。