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To study genetic mutations of methylenetetrahydrofolate reductase C677T and cystathioinine-β-synthase T833C related to homocysteine metabolism in patients with ischemic stroke, the MTHFR gene C677T gene mutation and the CBS T833C gene mutation were detected by PCR-RFLP or ARMS method in 74 patients with ischemic stroke and 83 normal people for control. Results showed that the frequencies of MTHFR genet homogenetic type(2.7%), heterogenetic type(51.4%) and T allele(28.4%) in ischemic group were higher than those in control group(1.2%, 39.8% and 21.1%, respectively).

为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶基因C677T和胱硫醚-β合成酶基因T833C位点碱基突变与缺血性脑卒中的关系,对74例缺血性脑卒中患者和83例健康对照者,采用聚合酶链反应-限制性片段长度多态性技术检测MTHFR基因C677T基因型,用扩增阻滞突变体系法检测CBS基因T833C突变。

Clinical experiment displays the dynamic compliances of the lung and PaO〓/FiO〓 in TNF-αAb group was higher than that in control group. The intube time in TNF-αAb group was much shorter than that in control group.

临床研究还显示,体外循环术后各时点肺动态顺应性和PaO〓/FiO〓用药组显著高于对照组;呼吸机辅助时间明显缩短。

The side effects in two groups were observed.Results 3~7 days after the end of treatment,the cure rate and efficacy rate were 64.3%and 82.5%in control group and 76.2%and 91.5%in trial group,respectively.3~7 days after menorrhea,the cure rate andefficacy rate were 65.9%and 83.3%in control group and 78.5%and 92.3%in trial group,respectively.There was a significant difference between two groups.

结果 停药后3~5 d,对照组的治愈率和有效率分别为64.3%和82.5%,试验组的治愈率和有效率分别为76.2%和91.5%;停药后下次月经来潮干净后3~7 d对照组的治愈率和有效率分别为65.9%和83.3%,试验组的治愈率和有效率分别为78.5%和92.3%;两组比较有显著性差异(P.05)。

In this study, we investigate the heat-induced inhibition of drug-metabolizing enzyme activity in mice fed with freeze-dried, heated freeze-dried or half amount autolyzed freeze-dried Brussels sprouts powder. 0.5% ethoxyquin diet was fed to another group of mice as a positive control. The study mice, four per group, were fed a diet consisting of 20% Brussels sprouts for 7 days. Each group had its own pair-fed group. We found significantly greater inductions of glutathione S- transferase, quinine reductase, and phase Ⅱ drug-metabolizing enzyme activities in groups fed within freeze-dried and heated freeze-dried Brussels sprouts than their pair-fed groups. These findings indicate that intestinal microflora still can hydrolyze glucosinolates without plant myrosinase activity, though the alteration of cytochrome- P-450 1A (CYP1A, a phase Ⅰ drug-metabolizing enzyme) induction was only 1.4-fold.

本实验欲进一步探討加热处理之抱子甘蓝对phase Ⅰ与phase Ⅱ解毒酵素活性之影响差异,实验分三组,抱子甘蓝(1)冷冻乾燥组(glucosinolate未裂解)(2)加热冷冻乾燥组(3)半量之裂解冷冻乾燥组(glucosinolate已裂解),(4)and 0.5% ethoxyquin diet was used as a positive control以2%重量混合成饲料,餵以小白鼠(4只/组)7天,结果发现,在第(2)组小白鼠GST phase Ⅱ酵素)活性显著上升,显示在植物裂解酵素不存在之状况下,肠胃道之微生物仍可促进裂解反应,但由CYP1A活性增加不显著(仅1.4倍)看来,根据定义:单独phase Ⅱ酵素活性增加,为monofunctional induction/inducer,可加速致癌物之代谢。

Simultaneously 15 samples of normal nephric tissue were used as control.The sections from these samples were subjected to immunohistochemical analysis with antibodies directly against uPA and PAI-1 by LSAB method. In this study we adopt semiquantitative analysis to determined the expression of these molecules , and utilized the relevant data processing and statistical analysis to evaluate the correlation between their expression and the clinicopathological features of RCC.Results: 1. The positive rate of uPA and PAI-1 of uPA in RCC were 72%(36/50)and 56%(28/50), respectively.But in control group there was nearly

正常肾组织标本中几乎无阳性染色。2、uPA表达水平与患者年龄、性别、肿瘤病理分级无关(均P>0.05),与T分期、淋巴结转移有明显的相关性(r=0.684,P<0.05;r=0.789,P<0.05),uPA高表达多见于T_(3-4)、有转移的RCC.3、PAI-1的表达水平与患者年龄、性别、肿瘤病理分级和T分期无关(P>0.05),与淋巴结转移有明显的相关性(r=0.800,P<0.05),PAI-1高表达多见有转移的RCC.4、对uPA和PAI-1行相关性检验,uPA在RCC中的表达与PAI-1的表达呈明显正相关(r=0.168,P<0.05)。5、uPA和PAI-1的表达与淋巴结转移的关系以Logistic回归法进行分析,结果显示uPA与区域淋巴结转移密切相关,uPA是淋巴转移的危险因子(RR=2.718,95%CI=1.150~7.170,P=0.024),PAI-1则不是淋巴转移的危险因子(RR=1.599,95%CI=0.624~4.102,P=0.328)。

Results In atropine group the function of isolated rats phrenic diaphragm was significantly less than that in control group (P<0.01). In atropine plus PAM-CI group the function of isolated rats phrenic diaphragm was similar to control group.

结果 阿托品治疗组大鼠与空白对照组大鼠的单收缩和强直收缩有明显区别(P<0.01),而阿托品加氯磷定治疗组大鼠与空白对照组大鼠的单收缩和强直收缩无明显的区别(P>0.05)。

Results: Thirty minutes after the application of NIPPV, the patients' dyspnea was improved markedly, respiratory rates and heart rates decreased, and moist rale disappeared rapidly. The patients in the treatment group improved more rapidly than those in control group. The arterial blood gas analysis showed that the PaO2 rosed more quickly in the treatment group than in the control group.

结果:治疗组NIPPV治疗30 min后呼吸困难明显改善,呼吸频率和心率明显下降,肺部湿性罗音消失明显,总体好转程度明显优于对照组,PaO2升高的程度和幅度均优于对照组。

Receivabk is the financial control of the most important, because we have too much experience tells us that receivable have no control over, the castles in the air is really dicalctum hanging on the wall and fell down in your pocket, you account budget seems to have $ 5 million to a profit of $ 5 million, not only do not have your bag, you may go in hundreds of thousands of you like semiconvergence.

应收帐款。应收帐款是财务控制中的重中之重,因为我们有太多的经验和教训告诉我们应收的控制不了,画饼充饥真的饼就挂在墙上,掉不下来在你口袋上,最后你帐上预算好像有五百万利润,最后这五百万不仅没有到你袋里,可能你还要亏进去几十万。

The principal best management practices for Costa Rica are: a well drained soil or a good drainage system in the field (banana yield is hurt with only a few hours of oxygen depletion in the root zone), b adequate control of nematodes, c adequate control of black sigatoka and d a good fertilizer program which includes rates of fertilizer equal or higher than 300-300-600 kg/ha/year of N- P2O5- K2O split in 12 applications during the year.

这些最好的管理措施为: a )良好排水土壤或田间良好排水系统(根区缺氧几小时就会损害香蕉产量), b )有效地防治线虫, c )有效地防治香蕉叶斑病和 d )良好的施肥计划,施肥量等于或高于300-300-600公斤 N - P2O5- K2O /公顷/年,一年中分12次施入。

The inhibition substances in Sorbus pohuashanensisHedl fruit not only restrained the seeds of wheat, cabbage from germinating but also restrained height and root growth. After the seeds of wheat, chinese cabbage had been soaked in the water extraction of pulp, seed and decoated seed for 8h, the seed germination rates were 92% and 84%, 89% and 65%, 94% and 78%, lower than the control, especially the water extract of decoated seed; and the root length and seedlings height were lower than the control, especially the water extract of pulp, and decreased in sequence of soaking time from short to long. So the simplest and effective method to eliminate pulp soluble inhibiting substances is to wash fruits by flowing tap water soon after collection.

在几种浸泡时间中,浸泡8小时的去皮种子浸泡液对白菜、小麦种子发芽率的抑制作用最为明显,其发芽率分别为65%、89%,但随着浸泡时间的延长而降低;浸泡8h的果肉浸泡液对白菜和小麦幼苗高生长和根伸长的抑制作用最为明显,种子和去皮种子浸泡液(8h)的抑制作用对小麦和白菜的抑制作用次之,随着浸泡时间的延长,果肉浸泡液的抑制作用逐渐减弱,因而采收下来的果实及时净种是清除果肉水溶性抑制物质简单有效的方法。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。