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And ZNF397nf function as transcription repressors. The different transcriptional regulation activity of the nf isoforms and their interaction with the fu isoforms would contribute to the complexity of the transcription regulation. To further examine the biological function of interaction between different isoforms we also analyze the potential role of ZNF191 and ZNF434 on signaling pathway. We found that ZNF191fu can significantly enhance the HSE-luciferase activity, while ZNF434fu can enhance the AP1-luciferase activity, then we analyze whether the nf isoforms have impact on the fu isoforms.

而这些成员的nf剪接本与它们对应的fu剪接本的转录调控功能有所不同，其中ZNF191nf与ZNF434nf剪接本的转录调控活性相对它们的fu剪接本显著降低，呈现较弱的转录抑制作用，但ZNF447nf剪接本却呈现出显著的转录激活作用，同时ZNF397nf剪接本则表现出显著的转录抑制作用，ZNF396nf剪接本的转录调控作用与其fu剪接本相当。nf剪接本这种与fu剪接本不尽相同的转录调控活性以及能与fu剪接本互作的能力，大大增加了转录调控作用的复杂性，这使得通过少量的转录因子作用来实现众多基因时空表达的不同成为可能。

Based on Logic regression model, the regional landslide threshold expression and the probability of rainfalls impact on the landslide is established.

利用逻辑回归模型建立了区域滑坡临界值表达式及降雨对滑坡的影响概率。

As the state a total ban on clay Shi Xinzhuan the progressive policies in place, the new hollow brick clay brick and concrete block is the unstoppable momentum of an impact on thousands of years of the Qin Dynasty brick-tile.

随着国家全面禁止粘土实心砖政策的逐步到位，新型的粘土空心砖和混凝土砌块砖正以势不可挡的势头冲击着几千年的秦砖汉瓦。

We review recent studies on the predictors of long-term response, and their impact on patient selection for CRT.

我们对近来研究中长期应答预测指标及其对患者选择CRT的影响进行了综述。

It is a comprehensive witch-hunter's handbook first published in Germany in 1487 that grew into dozens of editions spread throughout Europe and had a profound impact on witch trials on the Continent for about 200 years.

这是一个全面的女巫猎人手册首次出版，在德国，1487上升到几十个版本传遍欧洲产生了深刻影响女巫审判对大陆约200年。

It is a comprehensive witch-hunter's handbook first published in Germany in 1487 that grew into dozens of editions spread throughout Europe and had a profound impact on witch trials on the Continent for about 200 years.

这是一项综合性巫猎人手册出版第一增长到1487年在德国几十版本传遍欧洲产生了深刻影响，对大陆的巫婆审判约200年。

The compaction test was carried out to study their impact on compaction features on wind-laid sand by mixing powder particulate and coherent granule in different proportions.

为了研究它们对风积沙击实特性的影响，在风积沙中掺配不同比例的粉粒与黏粒，进行击实试验。

The moon shines from the gloom to the fog which rise up with the moon shining afar singing love songs to the people guiding the setting moon unexpected sorrow for this Singing the night feel sad Spring River Tiber, who lifts as Reed transpiration of water vapor in the search for tomorrow's dinner one person dinner only accompanied by an eating moon's bed watching for the moon also could not help feeling so sometimes on the road we can see the moon and talk I youth under short-term impact on the beautiful quiet now because it is lonely depressed mood, I often like the moon phases as turbulent as Tide or I may be bleak moon children....

月亮闪亮著从沉沉的雾气中升起来月亮闪亮著为远方唱著情歌的人指路残月生出的忧伤让今晚歌唱的人备感伤心月夜泛舟的人撩开芦苇在水气蒸腾中找寻明天的晚餐一个人的晚餐只有陪著月亮吃了一个人的床让月亮看著也有些惋惜所以禁不住有时就对著月亮倾诉心事可知我的青春短暂月影下美好的宁静现在因孤单却令人惆怅我的情绪常如月亮的圆缺如潮汐般汹涌或暗淡我也许是月亮的孩子。。。。

Based on the experiment, the flow variation and impact on release works is studied. The vortex theory is adopted to study the side shrinkage angle and optimum step of the bulkhead gate to improve the overflowing condition.

通过试验分析研究了闸后水舌的流态变化规律及其对泄水建筑物的影响；采用涡流理论分析研究闸后水舌侧收缩角的计算方法；根据侧收缩角计算出闸门槽的最优错距，从而改善闸孔出流的水流条件。

The new approach based on bio-impedance technology is influenced by many factors such as gastric secretion, components of test meal. But the non-nutrient fluid that has low electric conductivity and has no impact on stomach can be employed to investigate the relationship between the emptying curve of impedance and gastric volume.

胃阻抗法虽然受到胃液分泌、试验餐成分等多种因素的影响，但是选用对胃内影响较小、电导率低的非营养性液体可以获得阻抗信号和胃容积变化的对应关系。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新