查询词典 immunogenetic

Objective To investigate an association between CTLA-4 gone 3＇ untranslated region micro-atellite polymorphisms and IDC and to explore the immunogenetic pathogenesis of IDC.

细胞毒性T淋巴细胞相关抗原-4（cytotoxic T lymphocyte antigen-4，CTLA-4）主要在已激活的T细胞上表达，通过与CIY28竞争结合B7，抑制T细胞过度激活，维持免疫系统内环境稳定。

Nucleoprotein is also a major immunogenetic antigen for SARS; however, several tests have shown that N protein had the reactivity with other coronavirus positive sera. It is therefore an advantage of S protein as recombinant target antigen for SARS serum diagnosis compared with recombinant N protein. Moreover, S protein has been shown to be the major antigenic determinant that induces neutralizing antibodies and protective immunity to SARS-CoV, so it is also important in designing SARS genetic engineering vaccine.

SARS-CoV S 蛋白由1255 个氨基酸组成，体外表达如此大的蛋白很困难，而且表达蛋白的可溶性不高；其次，实验已经证实，全长S 蛋白含有大量无关的表位，致使表达的全长S蛋白对SARS 阳性血清的检出率低于S 蛋白片段；另外作为疫苗研究，S 蛋白上大量无关表位作为异体蛋白进入体内，会引发机体的过度免疫反应，这也是SARS-CoV 可能的致病机理之一。

Our molecular phylogenetic trees constructed by UPMGA and NJ methods were in general consistent with that based on biochemical,immunogenetic and cellular genetic markers except for differences in some populations.It was inferred from this study that all pig populations examined could be temporary classified into one breed,however,the population genetic character of Taihe Guanchao and Wanan Spotted pig populations should be further evaluated.

各类群的UPMGA和NJ聚类分析结果与采用生化、免疫和细胞遗传标记分析的结论不尽相同，在此基础上，结合现行分类方法，认为各受试猪群可暂时归并为赣中南花猪类型，但对泰和冠朝猪和万安花猪的品种归属性应作进一步分析。

To inquire into association between susceptibility to AIDP, AMAN and frequencies of HLA alleles and possible differencies in distribution of HLA alleles betwen AIDP and AMAN by genomic typing for HLA-class Ⅰ, class Ⅱ alleles, and to try to found out the effects of self intrinsic fators of GBS patients on occurence of two subtype from immunogenetic angle.

通过对AIDP和AMAN两种GBS亚型的HLA-Ⅰ类和Ⅱ类等位基因的分型，探讨两种亚型的易感性与HLA等位基因分型的关系以及两种亚型在HLA等位基因分布上可能存在的差异，从免疫遗传学角度寻找自身内在因素在GBS不同亚型发病中的可能作用。

This study indicatd that specific MHC class Ⅱ alleles or haplotype may confer the susceptibility or resistance to IMN in shanghei chinese hsn, which conformed and developed the theory that IMN had an immunogenetic basis.

本实验结果表明，MHC-Ⅱ类某些特异性等位基因和单倍型可能授与上海地区汉族IMN患者易感性或抵抗性，并与临床特征及病理类型有关，论证并扩展了IMN的发病机制存在免疫遗传背景的推测。

3Genetic factors play a major role inthe control of immune regulation,such as the expression of cytokines.An analysisof TNF〓 gene polymorphism in IgAN and HSP nephritis is beneficial to better un-derstanding of immunogenetic abnormalities in these diseases.But further inves-tigation on a large scale is necessary in order to find out the susceptibility genes orthe markers for a closely-linked susceptibility locus.

某些免疫相关基因是细胞因子表达、调控的决定因素，本实验通过〓基因多态性分析对部分肾小球疾病的遗传背景进行了有益的探索性研究，但是要最终找到致病基因或者连锁遗传标志，尚有待进一步的大规模研究。

By investigating the association ofIL-2-384T/G,-475A/T and -631G/A polymorphisms in the promoter regionwith IDCM in southwestern Chinese Han population, this study intends toexplore the immunogenetic pathogenesis of IDCM.

本文通过研究中国西南地区汉族IDCM患者IL-2基因启动子区-384T／G、-475A／T、-631G／A多态性与IDCM的相关性，探讨IDCM患者的免疫遗传学发病机制。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。