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Objective: To establish a mouse lymphopenia model via irradiation and to study its immune characteristics.

目的：以放射线处理建立小鼠淋巴细胞减少症模型并探讨其免疫学意义。

The Major histocompatibility complex of Macaca mulatta, also called Mamu antigen, is a gene cluster directly related to immune response. Evolution creates the highly polymorphic nature of the MHC genes, and this leads to changes in the number as well as the function of these genes in individual Macaca mulatto, and even the emergence of species-specific genes.

恒河猴是应用最广泛的非人灵长类实验动物，其MHC基因是一个庞大的与免疫功能密切相关的基因群，在进化过程形成了Mamu基因不同的存在状态，使得不同个体的Mamu基因在数量和功能上有所差异，同时有些个体还产生了特异性的MHC基因，它的多态性和免疫反应的复杂性相对应。

Western Blot indicated that AIF was selectively released before cytochrome C from the intermembrane space of mitochondria to cytosol, and that release needed Bax relocation to mitochondria. Results above suggest that caspase-independent cell death maybe occurred earlier than caspase-dependent cell death in staurosporine induced T lymphocytes apoptosis. Caspase-independent cell death is an alternative pathway of cell death which could guarantee the safe and noninflammatory removal of corpses when caspase was mutented or blocked in the cell, it plays an important role in maintaining the number of T lymphocytes and ensuring the proper function of immune system.

细胞caspase非依赖死亡方式可能是Caspase依赖性死亡方式的替代途径，它可以保证在Caspase发生突变或通路受阻时，T细胞仍然能够正常死亡，这对于维持T细胞的数量和保证免疫系统正常功能的发挥具有十分重要的意义。

Objective To analyze the genetic variation of rDNA-ITS2 of Schistosoma japonicum and Paragonimus skrjabini in order to avoid the cross reactions in immune diagnosis between schistosomiasis and paragon-imiasis.

结果2种方法构建的遗传系统进化树基本结构相似，日本血吸虫与斯氏并殖吸虫间存在较远的遗传距离，但二吸虫ITS2序列间有42.7%的相似性。

objective to study the efficacy of the tr/patoc 1 slide agglutination assay for vaccination new pentavalent whole cell vaccine for leptospirosis.methods using tr/patoc 1 slide agglutination assay to detect the searial of serum specimens of 100 healthy people after vaccination for leptospirosis and comparing with the microsopic agglutination test.results both basic immunizaton and 20 days after the enhanced immunization,their positive seroconversion rates were higher than 90% in tr/patoc 1 slide agglutination assay,they were not signficantly different between slide agglutination assay and mat,the antibody titer was greatly lower in 90 days after basic immunization.conclusion the tr/patoc 1 slide agglutionation assay was one of useful assays in evaluation the lately immune efficency of leptospira vaccination.

目的 采用tr/patoc 1玻片凝集试验评价钩端螺旋体疫苗免疫效果及应有价值。方法采用tr/patoc 1玻片凝集试验检测100名健康人钩端螺旋体疫苗免疫后的血清抗体变化，并与显微镜凝集试验比较。结果无论是基础免疫还是加强免疫20？d后，玻凝试验抗体阳性率高达90%以上，与标准的显微镜凝集试验比较差异无统计学意义，玻片凝集试验检测的抗体持续时间较短，90？d后阳性率已大幅度降低，表明sat检测的抗体是早期抗体。结论 tr/patoc 1玻片凝集试验操作简易，可以作为基层卫生机构监测钩端螺旋体疫苗近期免疫效果的方法之一。

In the control animals,the GAP-43-LI nerve fibers were found mainly distributed in association with vascular plexuses,with minor extension into the parenchyma of the inner zone of the periarterial lymphocyte sheath.In the immunized animals,in addition to denser vascular plexuses,more fibers appeared in the outer zones of periarterial lymphocyte sheath,the marginal zone,and the red pulp,all known to be the sites of active immune response.

于对照动物，脾GAP-43-LI神经纤维主要分布于血管周围，少量伸入动脉周围淋巴鞘的脾基质中，而在免疫刺激的动物，不仅血管周围的神经纤维明显增多，动脉周围淋巴鞘外层、边缘区和红髓等免疫应答活跃的部位也出现许多神经纤维。

Peripherial blood mononuclear cells pulsed with GST-MAGE-3 were able to present antigen to T lymphocytes, activate antigen-specific CTLs and induce special antitumor immune responses in vitro.

经GST-MAGE-3蛋白抗原冲击的胃癌患者外周血单个核细胞能在体外有效提呈抗原，激活抗原特异性CTL，诱导特异性抗肿瘤免疫应答。

The pathogens, which are transmitted by media of mosquitoes have to be able to avoid or defeat the defensive barriers in bodies of mosquitoes, such as peritrophic matyix, digestive enzyme, immune system, etc.

经蚊传播的病原体，必须能逃避或克服蚊体内众多的防御屏障，诸如：围食膜、消化酶、免疫体系等。

Objective To explore the enhancement of C3d molecule to the humoral immune response induced by polytope DNA vaccine.

目的 研究C3d分子对多表位DNA疫苗体液免疫应答的增强作用。

Berberine is mainly used to treat major used in enteric bacterial infection,recently,researches showed that Berberine can not only be used to treat cardiovascular disease,endocrine disease,nutritional and metabolic disease,central nervous disease,tumors,but also can improve immune function and anti-graft rejective reaction of skin besides its antibacterial action.

黄连素在临床上主要用于治疗肠道细菌感染，但大量研究和临床应用表明，黄连素除了有抗菌作用外，还可用于治疗心血管疾病、内分泌、营养及代谢疾病、中枢神经系统疾病、肿瘤等疾病，同时具有增强免疫机能及抗皮肤移植排斥反应等作用。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。