查询词典 hypoxia

The results show that the number of red blood cell hemoglobin concentration and hematocrit are significantly higher after hypoxia adaptation in the Gansu Zokor; however, its mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration decrease after hypoxia adaptation.

结果显示，甘肃鼢鼠低氧适应后红细胞数、血红蛋白浓度和红细胞压积均显著升高，而平均红细胞体积、平均红细胞血红蛋白及平均红细胞血红蛋白浓度明显下降。

In the stimulation of grave hypoxia reach to one extent,Gansu zokor may impellingly smooth launch of its own mechanism to hypoxia from molecular, cellular and structure level to the overall coordination,and not to appeared heart failure. Gansu zokor will remain survival at the hypoxic conditions with the stability in cardiac muscle structure and its nomal function.

综上所述，本研究结果说明甘肃鼢鼠虽长期生活在地下低氧环境中，但对严重的低氧环境仍比较敏感，在一定程度的严重低氧刺激下才会迫使其顺利启动其自身从分子、细胞水平到整体协调的低氧耐受机制，使心脏不至出现衰竭的现象，从而在心肌组织结构稳定的情况下，发挥正常功能，维持在低氧条件下的生存。

The Na+ and K+ currents of hippocampal neurons before and after hypoxia-reoxygenation with xionggui diwan pretreatment: Before hypoxia-reoxygenation, the ampli tudes of Ⅰ Na and J K of hippocampal neurons at the threshold point were very similar, without significant difference.

芎归滴丸预处理后缺氧-复氧前后海马神经元的Na+、K+变化：缺氧-复氧前海马神经元Ⅰ Na Ⅰk在阈值处的幅度很接近，差异无显著性意义。

Compared by middle-stage luteal cell, luteinized granulosa cells responded an increasion in PCNA even under hypoxic condition, which spoke for an important role of hypoxia in controlling the performance of cell proliferation. Similarity was proved between luteal cell and luteinized granulosa cells when it came to the performance of cell proliferation under a condition of hypoxia.

然而，意外地发现缺氧条件下黄体化粒性细胞之PCNA蛋白质表现量反而增加，此结果与中期黄体细胞之结果恰好相反，显示此时之细胞分裂旺盛而快速增生，与黄体发育初期之细胞生理相似，且缺氧条件可能扮演著重要的调控角色。

OLH or 8-bromo-cAMP were added to luteinized granulosa cells. Results indicated that, protein expression of HIF-1a, HIF-1b and VEGF had a better performance in hypoxia than in normoxic condition, but phospho-PKA, StAR and P450scc protein expression had weaker expression in the former condition than in the later one. As a result of decreasing secretion of progesterone the decreasing of phospho-PKA was suspected to have a role in the reduction of StAR and P450scc in the condition of hypoxia.

结果发现，黄体化粒性细胞於缺氧条件下其HIF-1a、HIF-1b与VEGF蛋白质表现量皆较正常氧高；同时，StAR及P450scc蛋白质表现量则降低，但3b-HSD不受缺氧影响；此外，藉由特异性抗体检测PKA讯息传递路径发现，PKA讯息传递路经於缺氧条件下磷酸化PKA（phospho-protein kinase A）蛋白质表现量下降，可能经此路径的调控造成StAR及P450scc蛋白质表现量下降，导致黄体化粒性细胞孕酮分泌量减少。

Effects of intermittent hypoxia, cold, restraint and their combinated stresses on the level of insulin secretion Simulated 2 km intermittent hypoxia (4 hours/day, continuation for 15 days) didn"t significantly influence rats" body weight gain.

间歇性低氧、低温、束缚及其复合应激对胰岛素分泌水平的影响模拟2km间歇低氧(4小时／天，连续15天)对大鼠的体重增重没有显著影响，而模拟5km间歇低氧(4小时／天，连续15天)显著抑制大鼠体重增重。

HIF-1α is an oxygen-regulated protein and is recognized as a positive factor to tumorigenesis. During nomoxia, HIF-1α is rapidly hydroxylated by prolyl hydroxylase then goes into 26S proteasome degradation pathway. During hypoxia, HIF-1α accumulates and dimerizes with HIF-1β to transactivate hypoxia-responsive gene expression.

中文摘要缺氧诱导性因子-1α(HIF-1α)为一种对於氧分压敏感的转录因子，在正常氧分压下HIF-1α很快就被prolyl hydroxylase氢氧化进入26S蛋白酶体降解，当细胞处理缺氧环境时HIF-1α会累积并与HIF-1β形成复合物进行转录活化的作用；HIF-1α所调控的基因包括影响能量供给、细胞生长、血管新生等，被认为在肿瘤发育过程扮演促进者的角色。

HIF-1α is an oxygen-regulated protein and is recognized as a positive factor to tumorigenesis. During nomoxia, HIF-1α is rapidly hydroxylated by prolyl hydroxylase then goes into 26S proteasome degradation pathway. During hypoxia, HIF-1α accumulates and dimerizes with HIF-1β to transactivate hypoxia-responsive gene expression.

缺氧诱导性因子-1α(HIF-1α)为一种对於氧分压敏感的转录因子，在正常氧分压下HIF-1α很快就被prolyl hydroxylase氢氧化进入26S蛋白酶体降解，当细胞处理缺氧环境时HIF-1α会累积并与HIF-1β形成复合物进行转录活化的作用；HIF-1α所调控的基因包括影响能量供给、细胞生长、血管新生等，被认为在肿瘤发育过程扮演促进者的角色。

Cell lines were co-tranfected with bi-plasmids and cultured at 1% O〓 condition, luciferase assay demonstrated that all of the expression systems with different domains could be hypoxia-activated. GAL-CAD achieved more than 100-fold induction in A549 cell and more than 40-fold in HepG2; expression level of the system markedly increased after addition of glycin arm, almost 10-fold enhancement in HepG2 cell. Because basic expression also increased, the induction fold by hypoxia decreased.

双质粒共转染不同细胞株后，在1％O〓环境下培养24h，荧光素酶活性检测结果提示含不同结构域的表达系统均有受缺氧激活的能力，其中GAL-CAD在A549中获得100倍以上的诱导，在HepG2中获得40倍以上的诱导；加入甘氨酸臂后该表达系统的转录活性大为增强，在HepG2细胞中增强了10倍以上，但是由于基础表达也有所增加，受缺氧诱导的倍数下降。

objective to investigate whether hypoxia preconditioning exist in adipose tissue,and construct the hypoxemic model of adipose tissue.methods after injected different density cocl2 to rat's subcutaneously of groin,use immunohistochemical method detect hif-1α protein,and use rt-pcr detect hif-1α mrna.results after injected different density cocl2,the adipose tissue of rat's groin express different degree of hif-1αprotein and hif-1αmrna.,and reach the peak when the density is 20-40 mg/kg and the time is 3 h.conclusion hypoxia preconditioning exist in adipose tissue,and the effect of preconditioning is most evidence when the density is 20-40 mg/kg and the time is 3 h.

目的 探讨脂肪组织中是否存在缺氧预适应现象，构建cocl2致缺氧的缺氧模型。方法不同浓度的cocl2大鼠腹股沟区皮下层浸润注射，分别用免疫组织化学法和rt-pcr法检测该区脂肪hif-1α蛋白和hif-1α mrna的表达情况。结果用不同浓度的cocl2行化学缺氧后在不同时间点观察有不同程度的hif-1α蛋白和hif-1α mrna表达，其中，在浓度为20～40 mg/kg，时间为3 h时脂肪组织中hif-1α表达达高峰。结论脂肪组织存在缺氧预适应现象；cocl2的浓度选择20～40 mg/kg，时间选择3 h时缺氧预适应效果较佳。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。