查询词典 hypoxia

Angiectasis, permeability were increased , inflammatory cell were transuded; The cardiac muscle injury conditions after hypoxia 4 h were similar with hypoxia 2h group, appeared lipid droplet, implied the oxidative metabolism of lipid got obstacle started from then; The cardiac muscle injuried conditions were got little improvement in hypoxia 6 and 8 hours team, mitochondria were increased and aggregatived, normal cell junction, sarcomere contract weaked; in hypoxia 10h group , mitochondria were increased and aggregatived obviously, a few glycogenosome were assembled, transverse tubule were expanded, all the changes may be the adaption of Gansu zokors in the hypoxia tolerance process to 4% hypoxia extent gradually.

在4%严重低氧耐受过程中，甘肃鼢鼠心肌超微结构在2h组出现血管扩张，通透性增加，有炎细胞渗出，异染色质边集；4h组心肌损伤状况与2h组接近，出现脂滴，提示脂类的氧化代谢在此时开始发生障碍，6和8h组心肌损伤状况逐渐好转，线粒体聚集增多，细胞连接正常，肌小节收缩较前有所减弱；10组线粒体增多聚集，线粒体脊增粗更为明显，少量糖原颗粒聚集，脂滴较前有所减少，横小管扩张增大变粗，出现了与能量代谢有关的结构适应性变化。

METHODS: While hypoxia-reoxygenation groups were not given any medicine intervention as control, the treatment of xionggui diwan 1×10-6mol/L was subdivided into xionggui diwan 1 × 10-6 mol/L + non-hypoxia and xionggui diwan 1 × 10-6 mol/L + hypoxia groups, and the treatment of xionggui diwan 10 × 10-6 mol/L was subdivided into xionggui diwan 10 × 10-6 mol/L + non-hypoxia and xionggui diwan 10 × 10-6 mol/L + hypoxia groups.

缺氧-复氧前后组分为两个亚组(即缺氧-复氧前、缺氧-复氧后)，均不进行药物干预；芎归滴丸1×10-6 mol/L组分为两个亚组(即芎归滴丸1.0×10-6mol/L+不缺氧组、芎归滴丸1×10-6mol/L+缺氧组)；芎归滴丸10×10-6mol/L组分为两个亚组(即芎归滴丸10×10-6 mol/L+不缺氧组、芎归滴丸10×10-6mol/L+缺氧组)。

Myspalax cansus (Rodentia, Myospalacinae, Myspalax)which lives on the loess plateau of our country. This unique underground rats life-long living under the cave, it developed many hypoxic tolerance protect mechanism to adapt its special circumstances at in organsall levels. In this study,we used Gansu zokor and SD rats (Sprague-Dawley)for the object, do serious hypoxia tolerance experiment, to explore the hypoxia tolerance extreme of Gansu zokor, analysis the difference hypoxia tolerance between Gansu zokor and SD rats at same oxygen concentration; The changes on their cardiac muscle organization structures in hypoxia tolerance process ; The expression of HSP70 between normoxic and hypoxic control in cardiac muscle organization of two animals , to find the relativity in all the results.

甘肃鼢鼠隶属啮齿目，鼢鼠亚科，鼢鼠属，是我国黄土高原特有地下鼠，由于终生营地下洞穴生活，使得甘肃鼢鼠发展出良好的低氧耐受保护机制，本研究以甘肃鼢鼠和SD大白鼠(Sprague-Dawley)为对象，进行低氧耐受实验，探寻甘肃鼢鼠的低氧耐受极限，比较二者低氧耐受的差异；以及低氧耐受不同时程，二者心肌组织显微和超微结构的变化差异；比较分析左心室组织中HSP70的表达变化和心肌耐受过程中组织结构变化的相关性。

Hypoxia-ischemia for 10 minutes group , 20 minutes group: our experiment showed that at 24 hours after cerebral hypoxia-ischemia, expression of MMP-9mRNA was maximally increased, individually, in the hypoxia-ischemia for 10 minutes group, MMP-9mRNA was greatly expressed within superolateral surface cortex of cerebrum, whereas in the hypoxia-ischemia for 20 minutes group, the labeling of hybridization for MMP-9mRNA was strongly appeared within the cortexof cerebrum both the cortex in the subsequence of medial surface at the periphery of the cerebral longigudinal fissure and the cortex in superolateral surface where also there showed a few stained fibers.

3缺氧缺血10分钟、20分钟组：缺氧缺血后24小时脑内MMP9 mRNA阳性表达至最高峰，缺氧缺血10分钟组大量表达在端脑背外侧面皮质内，缺氧缺血20分钟组在端脑内侧面后份大脑纵裂旁周围皮质及背外侧面皮质内呈强阳性表达，少数纤维呈亦阳性染色。

Compared to the respectively alone stress, cold + 5 km hypoxia (4 hours/day, continuation for 2 days) and restraint + 5 km hypoxia combinated stresses significantly inhibited body weight gain of rats, and the five stresses also markedly decreased hepatic glycogen contents, and increased plasma glucagon levels. 2. Effect of continual hypoxia on the level of insulin secretion Compared to the sea level normoxia control group, simulated continual 2 km hypoxia for 1-25 days (1, 2, 5, 10,15 and 25 days) did not significantly influence rats body weight, food intake and plasma insulin level.

连续性低氧对胰岛素分泌水平的影响与海平面常氧对照组相比，模拟2km连续低氧1-25天(1、2、5、10、15和25天)没有明显影响大鼠体重变化、摄食量和血浆胰岛素水平，但在低氧第2天显著升高肝糖原含量和血糖水平，在第10天明显升高血浆胰高血糖素水平，在第1天血浆皮质酮水平显著升高，在第1和第2天瘦素水平明显上升，然而在第5天瘦素水平显著下降。

But in SD rats, cardiac muscle fibers were fractured seriouly , contracted to wavilness obviously, then muscle fibers fracture were contracted like entasia by the hypoxia time increased , injury intensify , all the changes refered SD rats compensatory mechanism can not be transferred in this hypoxia degree. 3. Exposed to 4% oxygen concentration, the cardiac muscle ultrastructure of Gansu zokors had serious injury after hypoxia 2h.

在4%氧浓度的低氧耐受实验中，甘肃鼢鼠在低氧2，4h后，心肌纤维收缩明显呈波浪状，低氧时间延长至6，8和10h后，心肌显微波浪状收缩由强逐渐变弱，并逐渐恢复至正常状态，说明鼢鼠心肌在6h以后对严重缺氧环境开始代偿性适应；SD大鼠2h组心肌纤维断裂严重，收缩加强成明显的波浪状，随着低氧时间得增加，4h组呈严重成挛状收缩，损伤加剧，提示SD大鼠在这一氧浓度下已经无法正常调动其代偿机制。3。

Methods 20 rats were randomly divided into A, B, C, D and E group. The models of cerebral anoxia in group A and C were made by hypopiesia and hypoxia, and the models of hypoxia-reoxgenation were made in group B and D. 24h and 1h before establishment of models, ginsenoside Rb3 was injected peritoneally in rats of group C and D, respectively. The number and form of GABA-like immunoreactive neurons in hippocampus CA1 area of rats after brain hypoxia-reoxgenation were investigated with immunohistochemistry.

將大鼠隨机分为A、B、C、D、E5组，A、C组以低压低氧暴露製作大鼠脑缺氧模型，B、D组为缺氧－复氧模型。C、D组动物分别於制模前24h、1h 2次腹腔注射人参皂甙Rh3溶液；採用免疫组化法，观察各组大鼠在缺氧及缺氧－复氧处理后海马CA1区GABA免疫反应阳性细胞形態及数量的变化，並与正常对照组比较。

Adult Wistar rats, supplied by the Animal Center of that university,were divided by random lotting into control group, acute hypoxia group, and chronic hypoxia group.Hypobaric chamber was used to simulate hypoxia for 2and 30 days at an altitude of

成年Wistar大鼠，校动物中心提供，按随机抽签法分为对照组、急性缺氧组和慢性缺氧组，低压舱模拟海拔5 000 m连续缺氧2，30 d，复制动物急性和慢性缺氧模型。

Alone cold stress, simulated 2 km hypoxia stress (4 hours/day, continuation for 2 days)+ cold, 2 km hypoxia stress, 2 km hypoxia stress + restraint stress and alone restraint stress all significantly decreased rats body weight gain.

与各自的单独应激相比较，冷应激+5km低氧(4小时／天，连续2天)的复合应激，束缚应激+5km低氧的复合应激显著地抑制了大鼠体重的增重。

Sanchez ET ,Botella LM ,Velasco B ,et al. Synergistic cooperation between hypoxia and transforming growth factor2beta pathways on humanvascular endothelial growth factor gene expression. J Biol Chem ,2001,19,276:38527238535.[3] Blancher C,Moore JW,Talks kl,et al.Relationship of hyposia-inducible factor HIF-1alpha expression to vascular endothelial growth factor I nduction and hypoxia survival in human breast cancer cell lines.

肝细胞癌中缺氧诱导因子-1α、热休克蛋白70的表达】；综上所述，肝细胞癌发生后，由于血供不足诱导HIF-1α过度表达，应激状态下产生的HSP70通过减轻缺血性损伤，增加毛细血管的生成及减轻细胞凋亡等途径使肿瘤细胞的增殖、移行加快，促进恶性肿瘤的生长、浸润和转移，使肿瘤细胞在适应缺氧、能量代谢、细胞凋亡及转移中起重要作用。

Alternatively, the con- trollers can use the synchronous rectifier itself or loss- less inductor current-sensing methods to provide overload protection with lower power dissipation.

另外，康威特罗勒斯可以使用同步整流器本身或亏损减少电感电流检测方法，以提供低功耗过载保护。

Mr. Dauber's other Schatz hangs in his home movie studio.

多伯把沙兹的另一件作品挂在家里的电影室。