查询词典 hypoxia

Objectives: To observe the influence of Danshen to the expressions of mRNA and protein of local hypoxia inducible factor-1α(HIF-1α) during acute ischemia reperfusion injury of skeletal muscles in SD rats, and its effects on the changes in erythrocyte aggregation index, erythrocyte deformation index, local swelling coefficient and histology of the left cremaster muscles of SD rats during ischemia reperfusion injury, therefore to discuss the influence of Danshen to the oxygen environment and hemorheology of skeletal muscle during ischemia reperfushion injury.

目的：通过建立SD大鼠左侧提睾肌的缺血再灌注损伤模型，观察丹参对SD大鼠骨骼肌缺血再灌注损伤局部缺氧诱导因子1α（Hypoxia Inducible Factor-1α，HIF－1α）mRNA及其蛋白表达的影响、对红细胞聚集和变形指数的变化、局部肿胀系数的变化以及组织形态学改变的作用，探讨丹参对缺血再灌注损伤骨骼肌局部氧环境及血液流变性的影响。

But in SD rats, cardiac muscle fibers were fractured seriouly , contracted to wavilness obviously, then muscle fibers fracture were contracted like entasia by the hypoxia time increased , injury intensify , all the changes refered SD rats compensatory mechanism can not be transferred in this hypoxia degree. 3. Exposed to 4% oxygen concentration, the cardiac muscle ultrastructure of Gansu zokors had serious injury after hypoxia 2h.

在4%氧浓度的低氧耐受实验中，甘肃鼢鼠在低氧2，4h后，心肌纤维收缩明显呈波浪状，低氧时间延长至6，8和10h后，心肌显微波浪状收缩由强逐渐变弱，并逐渐恢复至正常状态，说明鼢鼠心肌在6h以后对严重缺氧环境开始代偿性适应；SD大鼠2h组心肌纤维断裂严重，收缩加强成明显的波浪状，随着低氧时间得增加，4h组呈严重成挛状收缩，损伤加剧，提示SD大鼠在这一氧浓度下已经无法正常调动其代偿机制。3。

Objective To study the influence of intrauterine hypoxia to offspring rat Ethology change and nerve cells in brain hippocampus degeneration and apoptosis.

目的研究宫内缺氧(intrauterine hypoxia ，IH)对子代成鼠行为学改变及神经细胞变性、调亡的影响。

Angiectasis, permeability were increased , inflammatory cell were transuded; The cardiac muscle injury conditions after hypoxia 4 h were similar with hypoxia 2h group, appeared lipid droplet, implied the oxidative metabolism of lipid got obstacle started from then; The cardiac muscle injuried conditions were got little improvement in hypoxia 6 and 8 hours team, mitochondria were increased and aggregatived, normal cell junction, sarcomere contract weaked; in hypoxia 10h group , mitochondria were increased and aggregatived obviously, a few glycogenosome were assembled, transverse tubule were expanded, all the changes may be the adaption of Gansu zokors in the hypoxia tolerance process to 4% hypoxia extent gradually.

在4%严重低氧耐受过程中，甘肃鼢鼠心肌超微结构在2h组出现血管扩张，通透性增加，有炎细胞渗出，异染色质边集；4h组心肌损伤状况与2h组接近，出现脂滴，提示脂类的氧化代谢在此时开始发生障碍，6和8h组心肌损伤状况逐渐好转，线粒体聚集增多，细胞连接正常，肌小节收缩较前有所减弱；10组线粒体增多聚集，线粒体脊增粗更为明显，少量糖原颗粒聚集，脂滴较前有所减少，横小管扩张增大变粗，出现了与能量代谢有关的结构适应性变化。

OBJECTIVE: To construct a novel adenoviral eukaryotic expression vector that can co-express mutant hypoxia-inducible factor-1 alpha (HIF-1α) target protein and humanized Renilla reniformis green fluorescent protein reporter molecule under normoxic conditions.

目的：构建能够同时表达突变型低氧诱导因子1α(hypoxia inducible factor 1 alpha，HIF-1α)目的蛋白和人源化绿色荧光蛋白(human renilla reniformis green fluorescent protein，hrGFP)报告分子的新型腺病毒真核细胞表达载体。

Myspalax cansus (Rodentia, Myospalacinae, Myspalax)which lives on the loess plateau of our country. This unique underground rats life-long living under the cave, it developed many hypoxic tolerance protect mechanism to adapt its special circumstances at in organsall levels. In this study,we used Gansu zokor and SD rats (Sprague-Dawley)for the object, do serious hypoxia tolerance experiment, to explore the hypoxia tolerance extreme of Gansu zokor, analysis the difference hypoxia tolerance between Gansu zokor and SD rats at same oxygen concentration; The changes on their cardiac muscle organization structures in hypoxia tolerance process ; The expression of HSP70 between normoxic and hypoxic control in cardiac muscle organization of two animals , to find the relativity in all the results.

甘肃鼢鼠隶属啮齿目，鼢鼠亚科，鼢鼠属，是我国黄土高原特有地下鼠，由于终生营地下洞穴生活，使得甘肃鼢鼠发展出良好的低氧耐受保护机制，本研究以甘肃鼢鼠和SD大白鼠(Sprague-Dawley)为对象，进行低氧耐受实验，探寻甘肃鼢鼠的低氧耐受极限，比较二者低氧耐受的差异；以及低氧耐受不同时程，二者心肌组织显微和超微结构的变化差异；比较分析左心室组织中HSP70的表达变化和心肌耐受过程中组织结构变化的相关性。

Hypoxia-ischemia for 10 minutes group , 20 minutes group: our experiment showed that at 24 hours after cerebral hypoxia-ischemia, expression of MMP-9mRNA was maximally increased, individually, in the hypoxia-ischemia for 10 minutes group, MMP-9mRNA was greatly expressed within superolateral surface cortex of cerebrum, whereas in the hypoxia-ischemia for 20 minutes group, the labeling of hybridization for MMP-9mRNA was strongly appeared within the cortexof cerebrum both the cortex in the subsequence of medial surface at the periphery of the cerebral longigudinal fissure and the cortex in superolateral surface where also there showed a few stained fibers.

3缺氧缺血10分钟、20分钟组：缺氧缺血后24小时脑内MMP9 mRNA阳性表达至最高峰，缺氧缺血10分钟组大量表达在端脑背外侧面皮质内，缺氧缺血20分钟组在端脑内侧面后份大脑纵裂旁周围皮质及背外侧面皮质内呈强阳性表达，少数纤维呈亦阳性染色。

Objective: Hypoxia-inducible factor-1 is a transcriptive factor that regulates genes involved in metabolism angiogenesis and infiltration.

目的：缺氧诱导因子-1(Hypoxia inducible factor-1，HIF-1)是凋亡肿瘤细胞在适应缺氧的核转录因子。

METHODS: While hypoxia-reoxygenation groups were not given any medicine intervention as control, the treatment of xionggui diwan 1×10-6mol/L was subdivided into xionggui diwan 1 × 10-6 mol/L + non-hypoxia and xionggui diwan 1 × 10-6 mol/L + hypoxia groups, and the treatment of xionggui diwan 10 × 10-6 mol/L was subdivided into xionggui diwan 10 × 10-6 mol/L + non-hypoxia and xionggui diwan 10 × 10-6 mol/L + hypoxia groups.

缺氧-复氧前后组分为两个亚组(即缺氧-复氧前、缺氧-复氧后)，均不进行药物干预；芎归滴丸1×10-6 mol/L组分为两个亚组(即芎归滴丸1.0×10-6mol/L+不缺氧组、芎归滴丸1×10-6mol/L+缺氧组)；芎归滴丸10×10-6mol/L组分为两个亚组(即芎归滴丸10×10-6 mol/L+不缺氧组、芎归滴丸10×10-6mol/L+缺氧组)。

Compared to the respectively alone stress, cold + 5 km hypoxia (4 hours/day, continuation for 2 days) and restraint + 5 km hypoxia combinated stresses significantly inhibited body weight gain of rats, and the five stresses also markedly decreased hepatic glycogen contents, and increased plasma glucagon levels. 2. Effect of continual hypoxia on the level of insulin secretion Compared to the sea level normoxia control group, simulated continual 2 km hypoxia for 1-25 days (1, 2, 5, 10,15 and 25 days) did not significantly influence rats body weight, food intake and plasma insulin level.

连续性低氧对胰岛素分泌水平的影响与海平面常氧对照组相比，模拟2km连续低氧1-25天(1、2、5、10、15和25天)没有明显影响大鼠体重变化、摄食量和血浆胰岛素水平，但在低氧第2天显著升高肝糖原含量和血糖水平，在第10天明显升高血浆胰高血糖素水平，在第1天血浆皮质酮水平显著升高，在第1和第2天瘦素水平明显上升，然而在第5天瘦素水平显著下降。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。