查询词典 hydrochloride

Objective To establish a HPLC method for determination of the content of arginine hydrochloride in arginine hydrochloride and glucose injection.

目的 研究建立高效液相色谱测定法测定盐酸精氨酸葡萄糖注射液中盐酸精氨酸的含量。

In Chapter 2 of this thesis, the kinetic equation of substrate reaction in presence of denaturant has been derived. A re-examination of the effect of high concentrations of guanidine hydrochloride on the inactivation of papain, taking into consideration the effect of high concentrations of guanidine hydrochloride on the Michaelis constant, showed that, for papain, the substrate gives no protection on its inactivation.

我们在第二章中推导了变性剂存在下的底物反应动力学方程，并在考虑了高浓度盐酸胍对酶催化反应米氏常数的影响的前提下，根据推导的动力学方程重新分析了盐酸胍存在下木瓜蛋白酶的失活动力学，结果表明底物对木瓜蛋白酶的失活没有保护作用。

HPLC method for determination of ciprofloxacin hydrochloride and hydrocortisone in compound ciprofloxacin hydrochloride eardrops was established.

建立了复方盐酸环丙沙星滴耳剂中盐酸环丙沙星与氢化可的松的HPLC测定法。

Objective To develop an HPLC method for determination of impurities in ephedrine hydrochloride and pseudoephedrine hydrochloride.

目的 建立盐酸麻黄碱和盐酸伪麻黄碱中杂质的高效液相色谱HPLC测定方法。

Objective To develop a method for determination of Ephedrine Hydrochloride in Ephedrine Hydrochloride nasal drops by HPLC.

目的 建立用高效液相色谱法测定盐酸麻黄碱滴鼻液中盐酸麻黄碱含量的方法。

On the basis of the kinetic equation of substrate reaction in the presence of urea or guanidine hydrochloride, all microscopic kinetic constants for the free enzyme and enzyme-substrate binary and ternary complexes have been determined. The results of the present studies indicate that:①In the presence of urea or guanidine hydrochloride, enzyme-substrate complexes lose their activity less rapidly than the free enzyme. Therefore, both substrates, NADPH and 7, 8-dihydrofolate, protect dihydrofolate reductase against inactivation.②The denaturation of dihydrofolate reductase by urea follows single-phase kinetics, and changes in enzyme activity and tertiary structure proceed simultaneously in the unfolding process, so it may be an"all or none"process.③The GdnHCl-induced unfolding of the dihydrofolate shows a biphasic transition, while the change in the enzyme activity is a single exponential process. The rate constant of inactivation is consistent with that of the fast conformational change. Therefore, the kinetic intermediate of protein unfolding should be a partially folded and inactive form.

我们根据在脲或盐酸胍存在下的底物反应动力学方程求得游离酶和酶底物二元、三元复合物的微观动力学常数，结果表明：①酶-底物二元、三元复合物的失活速度明显慢于游离酶，说明两个底物二氢叶酸和NADPH对酶的失活都具有一定程度的保护作用；②在脲作用下，酶的失活和构象变化均为单指数项过程，而且酶的活力丧失和三级结构变化是同时发生的，说明二氢叶酸还原酶的脲变性可能是一个"全或无"的两态过程；③在盐酸胍作用下，酶的构象变化为两相过程，而失活则是单指数项过程，酶分子构象变化的快相速度常数与失活速度常数基本一致，因此我们认为二氢叶酸还原酶的盐酸胍变性过程中存在一个没有活力、但仍具备一定空间结构的变性中间体。

Hydrastine(97.7%) was obtained with extracted rate 65%by extracting the Goldenseal with mixed Solvent;Berberine hydrochloride (99.9%) was obtained by adding hydrochloride acid to alcohol (alcohol∶H 2O=1∶1) solution of the extract and Hydrastine (99.5%) was gained by CLC method with the yield 1%.

原药材用混合溶剂直接提取分离，可得到含北美黄连碱 97.7%的结晶体，提取率达 6 5%；提取物经醇水溶解、酸化，可直接获得小檗碱盐酸盐结晶，纯度达到 99.9%；用柱色谱法，可得到 99.5%的北美黄连碱，收率约 1

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Is to produce benserazide hydrochloride, Indapamide, semicarbazide hydrochloride, DL-serine methyl ester hydrochloride mainly of pharmaceutical intermediates and other products, products in competitive markets at home and abroad, with vast potential for development.

现以生产盐酸苄丝肼，吲哒帕胺、盐酸氨基脲，DL-丝氨酸甲酯盐酸盐等为主的医药中间体产品，产品在国内外市场颇具竞争力，具有广阔的发展潜力。

The results of its intrinsic fluorescence spectroscopy and fluorescence phase diagram showed that when the guanidine hydrochloride concentration in denaturation solution was about 1.0 mol/L, there existed a partially folded intermediate of Bacillus amyloliquefaciens a-amylase during its unfolding procedure, which followed a three-state model; the result of its fluorescence probe showed that when the guanidine hydrochloride concentration in denaturation solution was about 1.0 mol/L, there existed some stable hydrophobic regions, which could interact with a hydrophobic reagent 8-anilino-1-naphthalene sulfonic acid, in the partially folded intermediate of Bacillus amyloliquefaciens a-amylase; and the results of fluorescence quenching using acrylamide and potassium iodide as quenchers showed the distribution of Trp residues in Bacillus amyloliquefaciens a-amylase in different denaturation solution, with the maximum number (8) of tryptophan residues in a partially folded intermediate Bacillus amyloliquefaciens a-amylase molecule could be quenched by potassium iodide; and the results of their protein electrophoresis and SEC showed that no aggregate or aggregate precipitation of Bacillus amyloliquefaciens a-amylase formed during the whole unfolding procedure of Bacillus amyloliquefaciens a-amylase induced by guanidine hydrochloride.

内源荧光光谱和荧光相图结果表明，当变性液中盐酸胍浓度约为1.0 mol/L时，芽孢杆菌a-淀粉酶的去折叠过程中出现一个部分折叠中间体，其去折叠过程符合&三态模型&；荧光探针结果表明，在溶液中盐酸胍浓度约为1.0 mol/L时，中间态芽孢杆菌a-淀粉酶分子中存在着能够与探针分子1-苯胺基-8-萘磺酸结合的稳定的疏水区域；荧光猝灭研究给出了不同程度变性的淀粉液化芽孢杆菌a-淀粉酶中的Trp的分布情况，结果表明中间态芽孢杆菌a-淀粉酶分子中能够被碘化钾猝灭的位于分子表面的色氨酸残基数目达到最大的8个；蛋白电泳和体积排阻色谱结果表明，在盐酸胍诱导的芽孢杆菌a-淀粉酶分子的整个去折叠过程中，不会以共价键或非共价键形式形成芽孢杆菌a-淀粉酶分子之间的集聚体或集聚体沉淀。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。