查询词典 histoplasmosis

However, after that time, six patients died, four of whom had taken infliximab. The causes of death in those taking the drug included histoplasmosis 4 weeks after the final infusion; Listeria encephalitis 3 years afterward; prostate cancer 3.5 years afterward; and natural causes 10 months later. The two who received placebo died from a suicide and a cerebrovascular accident.

但在这之后，6例患者死亡：其中英夫利昔单抗组4例——1例患者在末次输注4周后死于组织胞浆菌病、1例患者3年后死于李斯特菌脑炎、1例患者3.5年后死于前列腺癌，1例患者10个月后自然死亡；安慰剂组2例患者分别死于自杀和脑血管意外。

In 18 patients studied, common infections included HPV and histoplasmosis. Ten patients developed one or more malignancies, including nine myelodysplasia/leukemia, one vulvar carcinoma and metastatic melanoma, one cervical carcinoma, one Bowen's disease of the vulva, and one multiple Epstein-Barr virus leiomyosarcoma.

在所研究的18例患者中，常见感染包括HPV和组织胞浆菌感染。10例患者出现1种或多种恶性肿瘤，包括9例脊髓发育不良/白血病、1例外阴癌和转移性黑色素瘤、1例宫颈癌、1例外阴鲍温病(Bowen's disease)及1例多发性EB病毒平滑肌肉瘤。

Prompt diagnosis, solitary application of AMB, or allied application of itraconazole are possible the effective measure of decreasing case fatality of histoplasmosis.

本病早期发现和治疗是可以痊愈的，单用两性霉素B(Amphotericin B， AMB)或联用伊曲康唑可能是降低本病死亡率的有效方法。

For patients at risk of histoplasmosis and other invasive fungal infections, clinicians should consider empiric antifungal treatment until the pathogen are identified.

医护人员应先确认患者是否居住或曾至霉菌流行区旅游，若怀疑病患有组织浆菌病或其它侵入型霉菌感染，医师应考虑先以经验疗法的抗霉菌药物治疗直到病原菌被确定。

Research background: Choroidal neovascularization is a common cause of vision loss in patients, which often resulted from exudative Age-related macular degeneration、 pathologic myopia、 central serous chorioretinopathy、ocular histoplasmosis and angioid streaks, Rarely, CNV is seen in children, usually in association with inherited macular dystrophies. Despite extensive basic and clinical research, our knowledge of the complicated molecular mechanism of CNV is still limited, for these reasons currently used therapeutic approaches are insufficiently effective.

课题研究背景：脉络膜新生血管(choroidal neovascularization，CNV)是导致视力丧失的一种常见原因，多继发于渗出型年龄相关性黄斑变性、近视性黄斑变性、中心性浆液性脉络膜视网膜炎、眼组织胞浆菌病和眼底血管样条纹等眼病，在儿童罕见，主要与遗传性黄斑营养不良有关，尽管近年来进行了大量的基础和临床研究，但对CNV复杂分子机制的认识仍然非常有限，因此目前的治疗措施都不尽如人意。

One patient taking infliximab developed tuberculosis and one developed histoplasmosis. Five patients (four taking infliximab and one taking placebo) developed cancer. New autoimmune disorders developed in two patients taking infliximab and one patient taking placebo. Two patients developed optic neuritis and one developed a multifocal motor neuropathy; all three were taking the study drug.

英夫利昔单抗组1例患者发生结核病，1例发生组织胞浆菌病。5例患者(英夫利昔单抗组4例，安慰剂组1例)发生癌症。2例英夫利昔单抗组患者和1例安慰剂组患者新发自身免疫性疾病。2例患者发生视神经炎，1例发生多灶性运动神经病；这3例患者均服用了英夫利昔单抗。

Notable serious adverse events included culture-negative septic arthritis in a subject receiving leflunomide and fatal disseminated histoplasmosis considered unrelated to rAAV2-TNFR:Fc in a subject receiving adalimumab.

其他的严重不良反应包括1例服用来氟米特患者出现培养阴性的化脓性关节炎、1例用阿达木单抗治疗患者出现致命性播散性组织胞浆菌病（与 rAAV2-TNFR：Fc 无关）。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失