查询词典 hippocampus

Methods: A brain concussion was produced in rats using a simple pendulum device model. One control (n=12) and six experimental groups were used(n=12 in each group). The cerebral concussion groups were assigned to sacrifice times ranging from 1 day to 24days after injury.A Morris Water Maze memory paradigm was used to assess learning and memory function. Pycnosis degeneration or necrosis neurons in the locus cerebral cortex, dorsal hippocampus, dentate fornix and brainstem reticular formation were observed and counted after brain concussion. Cholinergic neurons in the basal forebrain and brainstem reticular formation were identified and quantitated using choline acetyltransferase.

应用自制单摆式闭合性机械打击装置建立脑震荡大鼠模型；成年SD大鼠随机分为1个对照组(n=12)和6个脑震荡组(即伤后1、2、4、8、16、24d，n=12)；应用Morris水迷宫(Morris Water Maze，MWM)实验评价大鼠的学习记忆功能；用光镜对大鼠的上述脑区的固缩变性坏死细胞进行观察和计数；用免疫组化方法检测基底前脑和脑干网状结构的胆碱乙酰转移酶(cholin acetyltransferase，ChAT)阳性细胞的表达。

There were no statistically differences between the 8th~ 14thday, the 15th - 21th day post-BC and the control group. During the rt~24tkday post-BC , pycnosis degeneration or necrosis neurons of the locus cerebral cortex, dorsal hippocampus, dentate fornix were significantly increased, then decreased gradually, but recovered to normal by the 24thday after BC, and especially in parietal cortex and piriform cortex the necrosis neurons were significantly increased than temporal cortex , and there were no statistically difference berween the left and the right side. Pycnosis degeneration or necrosis neurons in the brainstem reticular formation were markedly increased in the 4thday after BC, and there were no statistically difference among the other groups and the control group.

与对照组相比，BC后在大脑皮质、背侧海马和齿状回部位，固缩变性和不完全坏死细胞数先显著增加(P＜0.05)，然后逐渐减少，至24d基本恢复正常；顶叶、梨状皮质比颞叶皮质变性坏死细胞多，差异有高度显著性(P＜0.01)；大脑左侧比右侧变性坏死细胞稍少但差异无显著性；在BC后4d，脑桥核、斜方体核平面的脑干网状结构中固缩变性和不完全坏死细胞数明显增多(P＜0.05)，其它组间无显著性差异。

MSG could insult the functions and structures of specific brain areas of adult mice through blood-brain barrier. The ability of discrimination learning in Y-maze was affected markedly, especially in 4. 0g/kg MSG group, meanwhile, dark pyknotic and loss of neurons were shown in arcuate nucleus of hypothalamus, but not in hippocampus. Consistent changes occured in mitochondrial membrane protein bound 〓 by 〓-fluoresent probe, i.

MSG可以透过成年小鼠血脑屏障产生神经毒性作用。4.0g/kg MSG对小鼠空间分辨学习能力的损伤程度较2.5g/kg MSG更为明显，同时下丘脑弓状核神经元出现核固缩及神经元数目明显减少，相同处理未引起海马神经元的明显变化。

The research aimed to observe the inclusion body in pyramidale cytoplasm in hippocampus of cerebral cortex in shepherd dog with rabies.

观察患狂犬病的牧羊犬大脑皮层海马的锥体细胞浆内的包涵体。

In the stratum pyramidale of AD hippocampus, the puncta of synapsinⅠwere larger in size, surrounding both pyramidal cells and pretangles.

以上结果表明晚期AD患者海马synapsinⅠ仅表现为选择性区域性丢失。

From medial to lateral, the cerebral cortex can be divided into three parts: hippocampus, general cortex and pyriform lobe, there is no distinct boundary between them, but the cell organization is different.

从内侧到外侧，大脑皮层可分为海马、新皮质和梨状皮质三部分，三者之间无明显界线，细胞排布有所区别。

Objective: To study if Lomerizine protects the hippocampus neurons cultured in vitro from the injury caused by quinolinic acid.

目的：利用洛美利嗪研究钙离子拮抗剂对兴奋性氨基酸喹啉酸所致体外培养海马神经元损伤是否有保护作用。

Quinolinic acid ; hippocampus ; glutamate ; Alzheimer's ; disease ; learning ; memory.

喹啉酸；海马；谷氨酸；阿茨海默病；学习；记忆

Methods Injecting quinolinic acid into rat hippocampus after injecting D-galactose to form the dementia rat model.

在s.c.D-半乳糖造成大鼠亚急性衰老的基础上，双侧海马内注射喹啉酸造成类AD模型。

GLT can improve recessively changed neurons in hippocampus CA1 region.

GLT能改善大鼠海马CA1区神经元的退行性变化。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。