查询词典 hippocampus

Conclusion］The results suggest that the possible mechanism of antiepileptic effects of SVHRP is that to decrease of PENK expression in the hippocampus of animal of epileptic susceptibility.

结论］蝎毒耐热蛋白能够抑制红藻氨酸诱导大鼠癫痫敏感性的形成，前脑啡肽原可能参与其作用机制。

Here we examined the expression of one of the target genes from cDNA array screnning-cystatin C, a major cysteine protease inhibitor of mammalian animals, in the murine hippocampus at 3, 7, 15 and 30 days following perforant path transections.

我们对cDNA array筛选得到的一个靶基因-CystatinC，一个哺乳动物体内主要的半胱氨酸蛋白酶抑制剂，在鼠去内嗅皮层支配3，7，15，30天海马的表达进行了考察。

Cystatin C may be involved in the astroglia-mediated neural plasticity events in the hippocampus following perforant path transections.

Cystatin C可能和去内嗅皮层支配海马内星型胶质细胞介导的神经可塑性事件有关。

8 Fold in the hippocampus 10 days following perforant path injury, 32 were up-regulated and 152 down-regulated. Roughly the function categories of the target genes are: immunity reaction, environmental response, cell structure, membrane transport and protein turnover.

CustomcDNA array筛选的8000个cDNA克隆中有47个在去神经30天海马显示差异表达且表达变化在3倍以上，其中25个表达上调，22个表达下调；Northernblot实验表明cDNA array的假阳性率是较高的。cDNA microarray在大鼠中枢神经系统表达的6234种基因和EST序列中，筛选到了152个基因和EST序列在去神经10天海马差异表达，表达变化在1.5-2.8倍之间，其中表达上调的32个，下调的120个。

Increased concentrations to 2×10〓, 2×10〓mol·L〓, securinine potentiated both basal PS and the magnitude of LTP induced by HFS. 2、Effects of securinine on synaptic transmission in freely moving rats Rats were chronically implanted with a stimulating electrode in the perforant path of hippocampus and a recording electrode in the granule cell of dentate gyrus.

一叶萩碱对清醒自由活动大鼠海马齿状回突触传递活动的影响为了更直接的研究学习记忆与突触效能的关系，我们采取慢性种植电极，在大鼠清醒状态下，观察药物对近生理状态下大鼠突触传递的影响。

To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray.

为了阐明中枢神经系统损伤后神经可塑性的分子机制，本实验探索了多种方法，包括传统差异筛库、传统cDNA array和cDNA microarray，对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。

Methods 20 rats were randomly divided into A, B, C, D and E group. The models of cerebral anoxia in group A and C were made by hypopiesia and hypoxia, and the models of hypoxia-reoxgenation were made in group B and D. 24h and 1h before establishment of models, ginsenoside Rb3 was injected peritoneally in rats of group C and D, respectively. The number and form of GABA-like immunoreactive neurons in hippocampus CA1 area of rats after brain hypoxia-reoxgenation were investigated with immunohistochemistry.

將大鼠隨机分为A、B、C、D、E5组，A、C组以低压低氧暴露製作大鼠脑缺氧模型，B、D组为缺氧－复氧模型。C、D组动物分别於制模前24h、1h 2次腹腔注射人参皂甙Rh3溶液；採用免疫组化法，观察各组大鼠在缺氧及缺氧－复氧处理后海马CA1区GABA免疫反应阳性细胞形態及数量的变化，並与正常对照组比较。

Moreover, we established the model of apoptosis induced by corticosterone and explored the effect of gangliosides, which is a active component in pilous antler, on this apoptotic cell model. The effects of gangliosides on neurotransmitter release, neuronal filopodia formation, calcium signal cascade and 5-HTl A receptor-ligand competitive binding were also studied. 2. Theory study: The viewpoint on brain and kidney in traditional Chinese medicine and that in Western medicine were comparatively studied. The essence of the relationship between kidney and brain in traditional Chinese medicine Subsequently, in combination with the analysis on the results in the empirical study, we discussed the essence of the relationship between kidney and brain in traditional Chinese medicine from the viewpoint about the feedback mechanism of hippocampus-hypothalamic-pituitary-adrenal.

体外实验采用糖皮质激素建立神经细胞凋亡模型，研究鹿茸有效成分的干预作用，并从神经递质释放、神经细胞丝状伪足生成、神经细胞钙信号途径、5-HT_(1A)受体配体竞争结合等方面进行机制探讨。2、理论研究：比较中西医学对肾和脑的传统认识以及现代研究，分析中医学中肾和脑的现代科学内涵，结合实验研究结果，从现代生物学海马—下丘脑—垂体—肾上腺轴负反馈机制的角度对中医肾脑相关理论的实质进行探讨。

Objective: To observe the contribution of Qingnao drop pilula to the alteration of myristoylated alanine-rich C kinase substrate mRNA expression in acute multi-infarction hippocampus.

中文摘要：目的：观察清脑滴丸对急性脑缺血海马MARCKS mRNA表达变化的影响，探讨其对急性脑缺血损害的调节作用。

Qingnao drop pilula can alleciate histomorphology lesion of hippocampus when occurring acute multi-infarction, to turn slower MARCKS mRNA expression, may play a neuroprotective effect role through accommodating PKC-MARCKS signal transduction system.

清脑滴丸可以减轻急性脑缺血时海马组织损伤，下调MARCKS mRNA的过高表达，其机制可能是通过调节PKC-MARCKS信号转导系统而起到神经保护作用。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。