查询词典 hippocampus

Aim To observe differentiation of ES cells of mice in adult rat brain after transplantation into septum and hippocampus.

目的观察小鼠胚胎干细胞植人大鼠隔区和海马内后的分化情况，并对其作研究和分析。

By means of stereotaxis instrument, 1×105 BMSCs (2 μL) of passage 3 stained with Hochest33324 for 24 hours were transplanted into the left hippocampus at 24 hours, 72 hours and 7 day after induction of HIBD in the corresponding groups.

在脑立体定位仪下，24 h，72 h，7 d细胞移植组分别于造模后对应时间点，将体外培养3~5代且经Hochest33324标记24 h的鼠骨髓基质细胞2 μL脑内移植于左侧海马，约105个细胞。

Methods: Rat MSC was isolated and purified in vitro,labelled by Hoechst33342, stereotaxis imbed into CA4 of rat hippocampus.

近来研究发现，MSC可以分化为神经元样细胞、胶质样细胞等［1］，植入体内后对脑和脊髓的损伤性疾病有治疗作用［2］，为MSC替代治疗神经系统疾病提供了实验基础。

Methods: Rat MSCs was isolated and purified in vitro, labelled by Hoechst33342, stereotaxis imbed into CA4 of rat hippocampus. To kill rat and recipe brain after 1,2,4 weeks to be made to frozen section, amd to observe Hoechst33342-marked cells under fluorescence microscope.

分离大鼠MSCs体外培养、纯化，Hoechst33342标记后立体定向植入大鼠海马CA4区，1、2、4周后处死大鼠取脑，制作冷冻切片；用荧光显微镜观察Hoechst3342阳性细胞。

Results rcbf in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rcbf明显下降，以术后24小时最明显，至4个月时仍明显低于正常，呈慢性持续性下降的趋势；各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍，至4个月时记忆功能障碍持续存在。

Results rCBF in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously. rCBF showed a tendency to decline. The cognitive functions of rats were obviously reduced after 1 mon of the chronic cerebral hypoperfusion and lasted until 4 mon.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rCBF明显下降，以术后24小时最明显，至4个月时仍明显低于正常，呈慢性持续性下降的趋势；各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍，至4个月时记忆功能障碍持续存在。

Methods Chronic forebrain ischemia model was made by permanent occlusion of bilateral carotid arteries. The cognitive function of the rats were estimated by Morris water maze test and rCBF in prefrontal cortex, parietal cortex, hippocampus and subcortex was assessed by laser doppler flowmetry on any different timepoint after operation (24 h, 7, 14 d, 1, 2, 3, 4 mon).

采用双侧颈总动脉永久结扎方法制备慢性前脑缺血动物模型；应用激光多普勒血流仪检测各组大鼠术后不同时间点（术后24 h、1 w、0.5、1、2、3、4个月）额叶、顶叶、海马及皮质下区局部脑血流量；利用Morris水迷宫方法检测各组大鼠记忆功能。

IL-1βmRNA expression in the developmental brain in Wistar rat: IL-1β mRNA in hippocampus, cerebral cortex and subcortex was detected by postnatal day 1 and gradually increased with development, reached a peak at postnatal day 21, and then gradually decreased to lower level at adult; In P77PMC rat, IL-1β mRNA expression was similar to Wistar rat before postnatal day 14, then gradually increased and surpassed Wistar rat at postnatal day 28, reached a peak in adult.

原位杂交显示谷氨酸诱导Wistar大鼠惊厥和P77PMC大鼠听源性惊厥后脑内IL-1βmRNA表达情况。结果发现，两种不同惊厥模型大鼠惊厥后脑内IL-1βmRNA表达存在明显的差异。谷氨酸引起惊厥诱导脑内皮层、海马和丘脑IL-1βmRNA表达增高的程度远较P77PMC大鼠听源性惊厥为低，而且惊厥后IL-1βmRNA表达增加较慢，于4-8h达高峰，而听源性惊厥可于惊厥后2h迅速达高峰。但两种形式惊厥诱导脑内IL-1βmRNA表达最高的部位均是海马。

Objective To investigate the expression of P2X receptors in CA1 subfield of rat hippocampus and the effect of hypoxia on the expression.

目的 研究P2X受体各亚型在不同年龄大鼠海马CA1区的表达及低压缺氧的影响。

AIM: To investigate the expression of AMPA receptor subunit GluR1 in the hippocampus of rats.

目的：观察AMPA受体亚单位GluR1在大鼠海马的表达。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。