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Kindler noted. Patients who receied beacizumab had higher rates of hypertension and slighter higher rates of bowel perforation and gastrointestinal bleeding.

接受阿瓦斯丁治疗的患者中高血压的风险增加，肠穿孔和消化道出血的比例也轻度升高。

David Lammy, Minister for Higher Education, said: Higher education remains one of the best pathways to a rewarding career, and it is good to see that students recognise it as a good investment for their future.

高等教育司秘书长，David Lammy说：接受高等教育仍然是奔向锦绣前程的最好道路，并且应该让学生们意识到这对于他们的未来是一个优质投资。

While it is contrary that the more contents of Fe,Ca and P are in yellow soil at higher altitude than those in lateritic red soil;(4) The pine forest has the highest content of Pb,and the Pb content is higher in soil at low altitude than that in high altitude.

鼎湖山土壤二氧化硅，锰含量随着海拔梯度的上升而下降，赤红壤含量高于黄壤；然而铁含量则随着海拔梯度的上升呈上升趋势，赤红壤含量低于黄壤，钙全量含量和磷含量也是赤红壤低于黄壤。（4）土壤Pb马尾松林含量最高，随着海拔梯度上升含量有下降趋势。

Result:(1)Tau prevented neurons against Mn toxicity of low and middle concentrations. The ideal conditions can reach upon 4. 5 mM Tau added just, nearly no apoptosis cells could be detected.(2)The percentages of apoptosis intogether were lower than those in Mn just , being concentration-dependent relations with Taurine levels.(3)Mn induced DNA damage of neurons with dose-depedent, The higher of Mn concentration, the lengther of the comet tail and the higher percent comet-like cells. Tau incubated could weaken significantly the lesions of Mn towards DNA on the degree.

结果：(1)牛磺酸对中低剂量锰的毒性有一定的拮抗作用，单独加入牛磺酸效果最好剂量是4.5mM，视野下几乎不见凋亡细胞；(2)牛磺酸干预后培养神经细胞凋亡率低于相同剂量的单纯锰培养细胞组，且与牛磺酸浓度呈剂量依赖性；(3)锰引起培养神经细胞DNA损伤，表现在彗星尾长增加，彗星样细胞百分率增加；加入牛磺酸干预后，可明显改善锰造成的培养神经细胞DNA损伤。

The results of in situ hybridization and fluorescence quantitative PCR showed that the gene expression of dopamine receptors(including D1 and D2) in the prefrontal cortex and DRD1 in lentiform nucleus of SHR from the Kongsheng Zhenzhong Pill group is higher than that in the methylphenidate hydrochloride group and both groups are lower than that in the control group:the gene expression of dopamine receptors D2 in the lentiform nucleus from the methylphenidate hydrochloride group is higher than that in the Kongsheng Zhenzhong Pill group while both groups are lower than that from the control group.

原位杂交和荧光定量PCR表明，SHR大鼠前额叶皮质的多巴胺受体(包括D1和D2)和豆状核受体D1的基因表达，孔圣枕中丹组比盐酸哌甲酯组要高，且两者均低于对照组；豆状核多巴胺受体D2的基因表达，盐酸哌甲酯组要比孔圣枕中丹组高，且均低于对照组。

Results compared with model control group,dongbao gantai group, the level of body weight,liver index, tc ,tg, alt,ast in serum in tiaozhi hugan decoction group were lower significantly .the level of hld-c was higher.,the level of mda in tiaozhi hugan decoction was lower significantly, the level of sod was higher significantly（in all group p＜0.01）conclusion it suggests that the pharmacodynamics mechanisms of tiaozhi hugan decoction to fatty liver induced by high fatty diet are lowering body weight and liver index, adjusting lipometabolism, improving liver function and having anti-lipid peroxidation effects.

结果 与病理模型组、东宝甘泰组比较调脂护肝方组大鼠体重、肝指数血清tc值、tg值均降低，hld-c值增高，血清alt、ast、mda值均较低，sod值较高（各组比较p.01）。结论调脂护肝方干预非酒精性脂肪肝的药效机制为：降低体重与肝指数，调整脂质代谢，改善肝功能，抗脂质过氧化。

The level of HLD-C was higher.,the level of MDA in Tiaozhi Hugan decoction was lower significantly, the level of SOD was higher significantly（in all group P＜0.01）Conclusion It suggests that the pharmacodynamics mechanisms of Tiaozhi Hugan Decoction to fatty liver induced by high fatty diet are lowering body weight and liver index, adjusting lipometabolism, improving liver function and having anti-lipid peroxidation effects.

调脂护肝方干预非酒精性脂肪肝的药效机制为：降低体重与肝指数，调整脂质代谢，改善肝功能，抗脂质过氧化。

Bounding in eastern Fenghuang, similar to Te, the crustal thickness can also be divided into two sections: northwest high value section and southeast low value section, and there is roughly a positive correlation between crustal thickness and effective elastic thickness of the lithosphere, namely higher crustal thickness value corresponding to relatively higher Te value and lowerer crustal thickness value to relatively lower Te value, which reflects that the lithospheric strength is directly proportional to the crustal thickness in regional tectonic background.

以凤凰东为界，与Te值类似，地壳厚度也可以宏观分为南东低值段与北西高值段，地壳厚度大体上与Te值呈正相关关系，相应较大地壳厚度对应较高的Te值，较小地壳厚度对应较低的Te值，说明在大的区域构造背景下，岩石圈强度与地壳厚度成正比。

Among the nuclear genes, sequences of EF-1α are used most widely, and they are fit for studying the phylogenies at genus or higher levels; nuclear rDNAs are used less in aphids' phylogeny analysis, LWO is a new marker developed in aphids, and both of them are applicable for higher-level taxa above family..

核基因中EF-1α应用最广泛，适用于探讨属级及属以上的问题；核rDNA在蚜虫中应用较少，18S rDNA适用于探讨科级以上高级阶元的问题；LWO是新近在蚜虫中开发使用的一个新基因。

The higher VEGF-C expression and LVD expression in esophageal cancer, the higher risk of lymph node metastasis in esophageal cancer; podoplanin marked LVD is more precise than VEGFR-3 marked LVD, and expression of podoplanin correlates closely with high expression of VEGF-C and LVD. It is a satisfactory lymphangial endothelium marker.

癌旁组织LVD同VEGF-C的高表达及淋巴结转移密切相关，食管癌组织中podoplanin标记的淋巴管密度较VEGFR-3标记的淋巴管密度更为精确，是一种更为满意的淋巴管内皮特异性标志物。

Because all the New York rounders are taking care of the tourists here.

因为所有的纽约扑克牌手都在这里对付游客。

It may sound like I'm bragging, but it's really the best cherry pie in the world.

虽然听起来像在吹牛，但那真的是世界上最好吃的草莓