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A number of nucleic acid repair genes such as excision repair cross-complementing gene 1(ERCC1) and human xeroderma pigmentosum gene D(XPD/ERCC2),the level descent may be susceptible factors to one or certain kinds of tumors; but if these genes′ level are higher,the ability to repair damage and chemotherapy-induced genetic damage will be enhanced,it may be resistance to chemotherapeutic drugs.

一些核酸修复基因,如切除修复交叉互补基因1(ERCC1)及人类着色性干皮病基因D(XPD/ERCC2)的水平下降,可能会成为某种或某几种肿瘤的易感因素;但如果此种基因的水平较高,修复损伤的能力提高,对化疗药物所致基因损伤的修复能力也就增强了,那么可能对化疗药物产生耐药现象。

Based on soil radon gas survey in Quanzhou City and Jinjiang City, the authors conducted an investigation of the soil radon gas environment in an area of some 465 km2. The results indicate that radon gas concentrations in soils of Quanzhou and Jinjiang urban areas are at a lower level, whereas those in soils of Quanzhou and Jinjiang suburbs are at a fairly high level. It seems that the radon gas concentration is mainly related to geological background: radon gas concentrations in soils derived from weathering of adamellite, moyite, and biotite schist are higher than those in soils derived from weathering of other rock types.

通过泉州市、晋江市土壤中氡气测量,取得约465 km2土壤氡气环境调查成果,从结果来看,泉州市区和晋江市区土壤中氡气浓度普遍较低;市郊主要为山地,土壤中氡气浓度普遍较高;从土壤中氡气浓度水平的分布来看,土壤中氡气浓度水平主要与地质背景有关,二长花岗岩、钾长花岗岩、钾长浅粒岩及黑云片岩风化土壤中氡气浓度明显高于其他地质背景来源土壤。

Results Anergic T cells express high level of CTLA-4 on the cell surface in the late stages of an immune response, but the level of CD28 expression is a little higher than that of activated T cells during whole immune response.

结果与活化T细胞相比,无能T细胞在免疫应答的后期阶段表面表达高水平的CTLA-4分子,而CD28的表达则只较活化组T细胞稍高一些。

Blood pressure should be reduced to normal level to prevent heart and cerebral vessels to occur arteriolosclerosiswhen the blood pressure of hypertensive patient is not very highor the duration of illness is short. when blood pressure rises very high or the course of disease is long, blood pressure should be lowered to slightly higher than normal blood pressure level, so it can prevent arteriolosclerosis to be deteriorated further and can prevent the occurence of cerebral ischemia and infarction.

在血压升高幅度不大或起病不久的高血压患者,治疗时应将血压降至正常水平,以预防心脑血管发生动脉硬化;在血压升高幅度大或病程长者,治疗时应将血压降至比正常血压稍高的水平,即要防止动脉硬化进一步加重,也要预防脑缺血和脑梗塞的发生。

More natatores were found in ponds before drawdown when the water level was high. In contrast, more grallatores were recorded in ponds after drawdown when the water level was low. Waterbird species number and individual density in ponds were higher during drawdown than those before and after drawdown.

养殖塘在放水前水位较高时吸引更多游禽栖息,而在放水后水位较低时吸引更多涉禽;在放水过程中,养殖塘中水鸟的种类最多,密度最大。

After 44 h IVM, MOS level in the immatured ooeytes was higher than matured oocytes, and there was less MOS in nucleus than in the cytoplasm at 6 h after matured oocytes were activated; RNAi was performed before IVM, and all the three siRNA applied could successfully knockdown the level of c-mos mRNA, which were 0.08 ± 0.03, 0.11 ± 0.06 and 0.20± 0.06 times of the control group respectively, and the quantity of MOS was obvious decreased compared with the control group at the same stage.

本实验通过RT- PCR、免疫荧光激光共聚焦检测方法检测了猪卵母细胞在体外成熟培养过程中c-mos基因在转录水平、翻译水平上的表达以及蛋白的分布,并应用注射小干扰RNA方法对其进行了RNA干扰研究。

Thirty two point six percent (42/129) of menopausetransition women and 18.9%(60/318) of menopause women had breast structure changes,〓=9.26, P<0.01. The frequency of breast structure changes decreased with decreasing ofserum of 〓 level and increasing of age. Four (4/29, 13.8%) in HRT group had breaststructure changes, which disappeared after discontinuing HRT or reducing the dose of HRTin 3 subjects. Conclusions: Most of normal menstrual women and menopause transitionwomen experienced Mastalgia; Mastalgia occurred in 89.7% of subjects and lasted forabout 2 M. in the 1-year ccHRT; Image of breast ultrasound changed following menstrualcycle in normal menstrual women; Breast pain and breast structure change may be causedby higher 〓 and P level in luteal phase; The breast structure changes of HRT user weresimilar to that in normal women and were reversible.

大部分正常月经妇女和绝经过渡期妇女有周期性乳房胀疼,绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年中大部分使用者有持续约两个月的乳房胀疼;乳腺体层厚度随体内雌孕激素水平的下降和年龄的增加而逐渐萎缩,绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年后,对乳腺体层的厚度没有明显的影响;超声下乳腺结构改变主要受体内雌孕激素水平的影响,正常月经妇女中1/3的乳腺结构改变具有可逆性,绝经过渡期和绝经后妇女中有一半的乳腺结构改变的特征类似正常月经妇女具有可逆性的乳腺结构改变;绝经后妇女应用17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗1年后,少数使用者出现的乳腺结构改变可随药物剂量的调整或停药而恢复;对长期HRT使用者仍需加强乳腺的监测,长期HRT对乳腺的影响值得进一步研究。

Our previous studies have shown that ubiquitous overexpression of HmgD caused hemocytes proliferation and the formation of melanotic tumors in the Drosophila larvae. To clarify the mechanism of melanotic tumors appearance,we also generated RT-PCR analysis to test the transcriptional changes of PPAE and Spn27A,which encode the key factors in the phenoloxidasecascade pathway from larvae samples of mid-third instar,late-third instar and prior to pupation relative to wild type flies.Our result showed that in the HmgD overexpression mid-third instar larvae,the expression level.of Spn27A was lower than wild type,otherwise the expression level of PPAE was higher than wild type.It suggests that overexpression of HmgD affects the PO cascade pathway.

本研究组前期工作发现,过量表达HmgD引起果蝇幼虫体内血细胞增生,并出现黑色素瘤,为探讨HmgD过量表达导致了血细胞增生即形成黑色素瘤的分子机制,本研究分别提取三龄中期、后期和相对于野生型化蛹前时刻的幼虫的RNA,首先检测了编码酚氧化酶级联反应途径中的两个关键基因PPAE,Spn27A在突变体中的转录发生变化,结果发现,Spn27A在三龄中期的表达量低于野生型,而PPAE的表达高于野生型,表明过量表达HmgD影响了酚氧化酶级联反应途径,低水平的Spn27A不足以抑制PPAE的活性,活化的PPAE催化了PPO的活性,使其转变成有活性的PO,从而促进黑色素的生成,使果蝇体内产生黑色素瘤。

Study result suggest: The change of stock in RFCCU directly affect gasoline content. Gasoline content can be reduced through increasing the equilibrium activity of catalyst, controlling reaction level, increasing recirculating rate of gasoline and stability of gasoline level. Conclusions drawn from experiment is that optimization of operating condition has great effect on lowering olefine content of gasoline which can be reduced from 60% to 50%.Reducing reaction temperature is useful for lowering olefine content of gasoline, when the reaction temperature is raised, thermal cracking rate is higher than catalytic cracking rate, so that olefine content is increased. Raising catalyst-to-oil ratio is good for lowering olefine content. With conversion rate increased, the yield of LPG and coke is raised, the yield of gasoline is increased firstly and then decreased slightly, hydrogen transfer index is increased, so the olefine content is decreased.

研究结果表明:催化裂化装置的原料的变化直接影响到催化汽油的烯烃含量;可以通过优化催化装置的操作条件来降低催化汽油中的烯烃含量,其中通过提高催化剂平衡活性、控制反应深度、增加汽油回炼量、汽油深度稳定可以降低催化汽油烯烃含量,优化工艺条件对降低催化汽油烯烃含量有较大作用,汽油烯烃含量由60%降至50%左右;降低反应温度有利于降低催化汽油的烯烃含量,当反应温度的提高,热裂化反应速度提高的幅度大于催化裂化反应速度提高的幅度,汽油烯烃含量增加;剂油比的提高有利于降低催化汽油的烯烃含量,转化率提高,液化气产率提高,汽油收率先增加后略有下降,焦炭产率增加,氢转移反应指数提高,汽油烯烃含量下降;反应时间对产品分布及汽油烯烃含量有影响,增加提升管反应时间,液化汽、汽油产率提高,干气和焦炭产率增加。

Methods 120 SD rats were divided randomly into blank group, model group, Baoliezhi control group and Qianliening granule groups with different doses. The models were established with hypodermic injection of testosterone propionate at 4 mg/kg after orchiectomy, at the same time, these rats were gastric perfused with different drugs respectively for 30 days. The body weight, prostate weight, prostate index, morphological changes, the level of T and E2 were measured. Results The body weight in model group was significantly lower than that in control group (P.05), the prostate weight and index were obviously higher than that in control group (P.01). The prostate weight and index were decreased significantly in Qianliening granule groups with meddle and high doses (P.01), the level of testosterone was increased significantly and E2 was decreased obviously in Qianliening granule group with high doses.

将雄性SD大鼠60只,随机分成空白组、模型组、保列治治疗对照组、前列宁颗粒低、中、高剂量组,采用丙酸睾丸酮皮下注射引起大鼠前列腺增生模型,连续给药30d后,观察6组动物体重前列腺湿重前列腺指数前列腺组织形态血清睾酮雌二醇(E2)水平的变化结果模型组大鼠体重较正常组明显减轻(P.05),而前列腺重量和前列腺指数明显升高(P.01);前列宁颗粒中、高剂量组的前列腺重量和前列腺指数明显下降(P.01);前列宁颗粒高剂量组可明显升高大鼠血清T水平,降低E2水平,使T/E2比例升高。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力