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ARID (AT-rich interaction domain) protein is a transcription factor family in higher eukaryotes that regulates cell proliferation, development, and differentiation. Specificity of DNA binding ability in this family prefers AT-rich sequences, but some ARID family proteins are not sequence-specific DNA-binding proteins or they do not bind AT-rich sequences. We found two genes that encode ARID in Giardia lamblia genome database, garid1 and garid2. We analyzed the function of garid1 first. AU1-tagged gARID1 was found to localize to nuclei. During encystation, gARID1 mRNA level decreased emphatically, but protein level increased. We also found that gARID1 can bind AT-rich initiator of the cwp1 promoter by EMSA. Mutation analysis revealed gARID1 binding sequence was AGATC and AATAAAATA. We used ChIP to demonstrate that gARID1 can bind cwp1 gene promoter in vivo.

ARID(AT-rich interaction domain)蛋白质家族是真核生物的一种转因子，在许多同种的真核生物有它的同源基因，这个家族的蛋白质通常与调控细胞的生长、发育和分化的作用有关，而这个家族的蛋白质和DNA的结合能，各种ARID蛋白质的专一性尽相同，过大致上偏好於和AT-rich的序结合；我们已经在形鞭毛虫的基因组中找到个含有ARID 的基因，分别是garid1和garid2，我们首先对於garid1做分析；将AU1标记接到gARID1转染形鞭毛虫，用免疫萤光染色可发现gARID1存在於细胞核中。gARID1的讯息RNA在囊体化后会明显下，过其阳性染色和蛋白质表现有明显增加；EMSA实验中也发现gARID1会明显的与cwp1基因启动子之AT-rich initiator结合，经由突变序分析，也显示gARID1的结合序为AGATC和AATAAAATA，随后我们也用ChIP证明gARID1在细胞内也的确会和cwp1基因的启动子结合。

Results: The tHey and blood fat level in blood plasma and expression of MCP-1mRNAof aorta on model group is obviously higher than that of control group (P＜0.05);the result of immunohistochemistry shows that the expression of VCAM-1 and MMP-2enhanced, Bcl-2 is lower; aorta slice shows endarterium discontinuation, strippingpartly, smooth muscle cell arrange puffly and chaotic, infiltration of lipoid ofdifferent degree are observed in aorta wall, pathological changes suffusion, morexanthoma cell, plaque protrude lumens. The they and blood fat level in blood plasmaand expression of MCP-lmRNA, VCAM-1, MMP-2 of aorta on intervention group aremuch lower than that of model group (P＜0.05); Bcl-2 of intervention group isstrengthened, and the pathomorphology and immunohistochemistry of aorta showpathological changes are slighter than model group.

结果：模型组，血浆中同型半胱氨酸浓度、血脂水平、主动脉MCP-1mRNA表达显著高于正常对照组(P＜0.05)，免疫组化示主动脉内皮细胞VCAM-1、MMP-2表达增强，Bcl-2表达降低；主动脉切片发现动脉内膜不连续，部分剥脱，平滑肌细胞排列疏松、紊乱，主动脉壁均见到程度不同的脂质浸润，其病变弥漫，泡沫细胞较多，可见斑块突出管腔；干预组，血浆中同型半胱氨酸含量、血脂水平显著低于对照组和模型组(P＜0.05)，主动脉MCP-1mRNA、VCAM-1、MMP-2表达显著弱于对照组和模型组(P＜0.05)，Bcl-2表达增强(P＜0.05)，主动脉病理形态学和免疫组织化学检测示病变轻于模型组。

The expression level of cAPN gene mRNA in lung,glandular stomach and jejunum were higher than that in other tissues,and the expression level of it in bursa of Fabricius and spleen were lower than that in other.The results also reflected that the tropism of IBV is closely related to the cAPN content diversity.

表明cAPN的表达与IBV亲嗜组织存在着密切的相关性，同时也侧面反映了IBV组织嗜性的差异在一定程度上取决于机体不同组织器官cAPN的含量差异。

The expression level of cAPN mRNA in lung,glandular stomach and jejunum were higher than that in other tissues,and the expression level of it in bursa of Fabricius and spleen were lower than that in other.

结果显示，随着日龄增加，肝、脾、法氏囊、回肠、肾等组织中的cAPN表达量相对稳定，肺、腺胃、空肠等组织中的cAPN表达量呈现持续下降趋势，而十二指肠中的cAPN表达量持续上升，但盲肠、空肠中的cAPN表达量规律性不强且波动较大。

"Water seeks its level," continued Mr. Gann.You can force it higher with a pump, but when you stop pumping it requires no force to cause it to return to its former level.

"水往低处流"，江恩先生接着说道：你可以强行用抽水泵使它到更高的水位，但是当你停止泵水时，不需要任何外力施加给它因为他要返回到它从前的水位去。

Results:The level of serum L fucose in patients (18.17±5.98)μg/L(P.01) was significantly higher than that in normal group (8.8±1.94)μg/L(P.01) The level of L fucose in sera w...

结果：患者组的血清 L岩藻糖含量为（1817±596）μg／ L，细胞毒指数为（063±011）。

The results of the experiment indicated that the average body weight of gosling and daily gain were higher significantly in low energy treatment than in high energy treatment (P.01), and under a certain level of energy, body weight and daily gain went up with the increasing of the level of protein and feed conversion ratio was improved.

本次试验表明低能组的平均体重和日增重要极显著的高于高能组(P＜0.01)，在能量水平一定的条件下，体重、日增重随着蛋白质水平的提高而提高，同时料肉比也得到一定程度的改善。

The reason is that Chinese traditional aesthetic standard advocates natural and implicative beauty and stresses plain face toward the sky to a certain extent; on the other hand, in the more developed regions, the consumption of color cosmetics is higher, and the development level of color cosmetics market is closely related to economic development level.

这在一定程度上是因为中国传统的审美观更提倡自然的、含蓄的美，讲究素面朝天；另一方面，经济越发达的地区，彩妆的消耗量也越高，彩妆市场的发展程度与经济发展程度息息相关。

In interglacial periods, such as at the present time,global sea level rose to its present level and higher, and marine ''.

几次间冰期间，全球的海平面升至目前及更高的水平，并沉积了海洋沉积物。

In interglacial periods, such as at the present time,global sea level rose to its present level and higher, and marine sediments were deposited.

几次间冰期间，全球的海平面升至目前及更高的水平，并沉积了海洋沉积物。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。