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Radiolabeled pharmacological binding assay showed: 1 BmK AS bound specifically to a single class of non-interacting binding sites on both rat brain and cockroach nerve cord synaptosomes with high affinity and low low capacity. The association of BmK AS with both synaptosomes was quick to reach equilibrium, but the dissociation seemed to be only partial. The specific binding of BmK AS was independent of membrane potential, and couldn't be modified by veratridine. Moreover, the binding of BmK AS could be inhibited by native BmK AS, BmK AS1, BmK IT2 and BmK IT on both synaptosomes, but not or partially inhibited by BmK Ⅰ and suggesting BmK AS type neurotoxins might bind to a distinct receptor site on mammal and insect sodium channels with a similar manner from β-scorpion toxins.

二。蝎毒素多肽配体与哺乳动物和昆虫靶离子通道受体的药理结合特性及其靶结合位点的研究:经放射性标记结合和竞争抑制实验表明:1)BmK AS在大鼠脑和蟑螂神经索突触体上有单一非协同性高亲和力低结合容量结合位点,能快速结合并达到平衡,但仅能部分解离,其结合不依赖于膜电位,也不受藜芦碱调节,天然的BmK AS,BmK AS-1,BmK IT2和BmK IT可抑制〓AS与两种突触体的特异结合,而BmK Ⅰ无或仅有部分抑制效应。

It has a great realistic significance to develop the investigation of the advanced manufacturing technology for composite materials, to achieve the high performance, low defect and low cost for the large aerobus project in Medium and Long term Development for China\'s Science and Technology and in Eleventh Five-Year Plan.

针对国家中长期科技发展规划与&十一五&规划中确立的大飞机研制项目,开展复合材料先进制备技术研究,实现高性能、低缺陷、低成本的目标,具有重大的现实意义。

In search of environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of anthranilic acid esters containing N-pyridylpyrazole were designed and synthesized. All of the compounds were characterized and confirmed by IR, 1H NMR, MS and elemental analysis.

设计,合成了8个新的含N-吡啶基吡唑杂环的邻氨基苯甲酸酯类化合物,结构经FTIR, MS, 1H NMR 和元素分析确证,并且采用X-射线衍射分析方法确证了具有较好生物活性的化合物14d的结构。

Benincasa hispida Cogn. contains various mineral elements and vitamins, with a relatively high level of potassium and low sodium, with low heat energy and no fat.

冬瓜含有多种矿物质和维生素,高钾低钠,不含脂肪,热能低,营养质量指数表明属优质食物。

The silicone rubber membrane used in SRMBR is a polymer-made non-porous material. It is hydrophobe and non-permeable to inorganic salt, and has the high selective ethanol permeability. Compared to the conditional separation technology, the pervaporation through SRM has the advantages of low-cost and low-pollution, especially applicable to separating volatile matter from organic matter-water system or organic-organic matter system.

其中的硅橡胶膜作为一种均相聚合物材料无孔膜,具有不透无机盐成分、疏水和对乙醇有较高选择透过性等特点;与传统分离技术相比,硅橡胶膜的渗透蒸发分离过程具有低能耗、污染少等优点,尤其适用于在有机物-水或有机物-有机物体系中分离挥发性有机物组分,现已用于发酵下游产物分离处理的试验研究中,并取得初步成效。

And countries was 5. 4%. And the control rate was 2. 9%, in which that in cities was 4. 2% and countries was only 0.9%. From these data we knowed that three rate of hypertension very low. The traditonal risk factors of cardiovascular diseases including overweigh, fat, alcohol, high salt intake, hypokalemia, hypocalcemia of cardiovascular diseases and low animal protein intake have been known, but these factors only explained half of cardiovascular diseases. So, it is necessary to find out and recognize the new risk factors.

心血管疾病的传统危险因素(体重超重和肥胖、饮酒、膳食高盐、低钾、低钙、低动物蛋白质)已经早已被认识,在不同的地区和不同的人群也进行了样本量不同大小的流行病学研究和基础研究,但研究表明传统的危险因素只能解释50%的心血管疾病,仍有50%的心血管疾病不能用传统的危险因素来解释,因此有必要认识和寻找新的危险因素。

There were interactions between variated genotype and low intake of fresh vegetables, fresh fruits and high drinking of alcohol in cardia cancer group. While the interactions between variated genotype and low intake of pean products, fresh fruits were observed in non-cardia gastric cancer group.

变异基因型与新鲜蔬菜、水果摄入少和常饮酒在贲门癌发生中存在交互作用,与豆制品和新鲜水果低摄入在非贲门部胃癌发生中存在交互作用。

Result The results indicated that the content of NO in liver, lung and skeletal muscle of high-dose group and in liver of middle dose group were significantly higher than that of control group and low-dose group (P.01). The content of NO in lung and skeletal muscle in middle dose group were higher than that of low-dose group and the control group (P.05). The content of NO in cardiac muscle in control group was higher than that of other group significantly (P.01). Tibetan Saussurea involucrata Kar.

结果]结果表明,高剂量组的肝、肺和骨骼肌和中剂量组的肝中一氧化氮含量中显著高于对照组和低剂量组,差异极显著(P.01);中剂量组的肺和骨骼肌中一氧化氮含量高于对照和低剂量组,差异显著(P.05);对照组的心肌中一氧化氮含量高于各药物组,差异极显著(P.01)。

It introduces the production control of low phosphorus and low carbon high silicon silicomanganese and the measures and crafts requirement of decreasing phosphorus and carbon.

论述了低磷低碳高硅锰硅合金的生产控制和降磷降碳措施以及工艺要求。

The low-phosphorus and low-carbon Al-Si-Mn ferroalloy is produced with aluminium and common silicomanganese in certain proportion and through adding proper amount of Ca-Ba dephosphorizing agent for high temperature dephosphorizing and decarbonizing and adding proper amount of pure aluminum and clean waste steel.

本发明按一定比例的铝、普通硅锰合金,加适量的钙、钡系脱磷剂进行高温脱磷脱碳,再根据产品成份的要求补加金属锰,加入所需的纯铝及纯净废钢,获得的低磷低碳铝硅锰铁合金的组成为:Al 5~20%,Mn 50~70%,Si 8~20%,C≤1.0%,P≤0.1%,S≤0.03%,余量为Fe。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。