查询词典 herpes simplex

Inspection of the oral mucosa may faciltate diagnosis of such diseases as pharyngitis, tonsillitis, mucositis, oral candidiasis or oral ulcerations, each of which may present clues to such diseases as SLE, HIV infection, herpes simplex, leukemia, megaloblastic anemia, or Behcet's disease.

检查口腔粘膜有助于咽炎、扁桃体炎、粘膜炎、口腔白色念珠菌病或是口腔溃疡的诊断，从而为系统性红斑狼疮、艾滋病、单纯疱疹、白血病、恶性贫血或 Behcet 病等疾病提供线索。

Objective To analyze clinical characteristics of 8 cases of MELAS syndrome that misdiagnosed as herpes simplex virus encephalitis.

目的分析误诊为单纯疱疹病毒性脑炎的8例线粒体脑肌病伴乳酸血症和卒中样发作综合征的临床特征。

Objective To analyze clinical characteristics of 8 cases of MELAS syndrome that misdiagnosed as herpes simplex virus encephalitis.

线粒体脑肌病伴乳酸血症和卒中样发作综合征具有线粒体脑病、高乳酸血症和卒中样发作的特征，确诊主要依赖临床表现和肌肉病理检查。

MELAS syndrome ; herpes simplex virus encephalitis ; clinical manifestation

线粒体脑肌病伴乳酸血症和卒中样发作综合征；单纯疱疹病毒性脑炎；临床特征

A randomized double-blinplacebo-controlled trial of cidofovir gel for the treatment of acycl-ovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDs.

本研究目的在于通过用&中效作用原理&对药效的分析，为中药方剂组方配比提供科学的实验依据。

Herpes simplex virus HSV -based vectors have primarily been developed for neuronal gene delivery , taking advantage of the virus 39 natural neurotropism .

单纯疱疹病毒为基础的载体主要是发达国家的神经元基因传递，利用病毒的自然神经性。

Like other alpha herpesvirus such as herpes simplex virus type I, varicella-zoster virus and bovine herpesvirus type I, PRV also has some typical characteristics of alpha herpesvirus, including latency and neurotropism.

与同属α—疱疹病毒亚科的人单纯疱疹病毒、水痘-带状疱疹病毒和牛疱疹病毒Ⅰ型等一样，PRV具有潜伏感染和神经嗜性等α—疱疹病毒的典型特征。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Thus, in polyarthritic rat, a model of chronic inflammatory pain, we demonstrated that herpes simplex irus ector mediated oerexpression of proenkephalin A in primary sensory neurons at the lumbar leel elicited both antihyperalgesic and anti-inflammatory actiities.

在一个慢性炎症性疼痛模型－多关节炎鼠上，我们证明单纯疱疹病毒媒介介导的前脑啡肽在腰水平初级神经原的过度表达引起了抗痛觉高敏和抗炎症活动。

OBJECTIE To ealuate the effect of herbal eye drop of Reduqing and potentialization of ultrasonic nebulous adiministration of Reduqing on experimental herpes simplex keratitis in rabbits, the acute toxicity test and the irritating eye reaction.

目的 评估中药热毒清滴眼液对兔实验性单纯疱疹性角膜炎(herpessimplexkeratitis ，HSK)作用和超声雾化强化给药的疗效及急性毒性与眼的刺激反应。

They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性，但我大喊，并在他们的方向扔石头让他们过的线索，远离我，以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。