查询词典 hemopoietic

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

CD117; hemopoietic stem cells ; dendritic cells ; directional differentiation

CD117；造血干细胞；树突状细胞；定向分化

The results showed that there were immature cells (2%-10%) and erythroblast, and puncture of bone marrow revealed myelodysplastic features involving multiple hemopoietic lineages in bone marrow of 19 patients.

结果表明： M6患者的外周血中均可见幼稚细胞（2％-10％）及有核红细胞，骨髓穿刺细胞学检查显示19例伴有多系细胞发育异常，累及二系细胞或三系细胞。

RESULTS HECu could increase peripheric white cell counting and accelerate the transformation of hemopoietic stem cells into erythron pregnitor cells significantly.

结果HECu能升高60Co辐射小鼠的外周血白细胞计数，促进60Co辐射小鼠和正常小鼠的造血干细胞向红系转化。

Objective:To study the influence of lead poisoning on viscera growth and hemopoietic system in neonatal Mongolian gerbil.

目的 ：研究铅对新生期长爪沙鼠脏器发育和血液系统的影响。

To study the sensitivity of hemopoietic organ of the silkworm to heavy ion beams, hemopoietic organs of the larvae were locally irradiated with carbon-ion beams (12C5+), and the changes in the hemocyte density were investigated.

为了研究造血器官对重离子射线的感受性，研究了碳离子射线（ 12C5+）局部照射家蚕幼虫的造血器官后血液中的血球密度的变化。

It was so concluded that silkworm hemopoietic organs were related to the formation of hemolymph proteins, and due to the decrease of hemocytes caused by functional disruption of hemopoietic organs, synthesis of protein in fat body was affected and protein components in hemolymph changed.

由此认为家蚕幼虫造血器官与血淋巴中的蛋白质成分有关，造血器官的机能障碍、血球的数量减少可影响脂肪体中蛋白质的合成，从而使存在于血淋巴中的蛋白质成分发生变化。

BACKGROUND: Compared with adult mesenchymal stem cells, yolk sac-derived MSCs of early embryo have stronger self-renewal capacity and plasticity. Moreover, they could differentiate into angioblast and hemopoietic stem cells during embryonic development and trigger embryonic angiogenesis and hemopoietic tissue development.

背景：与成体间充质干细胞相比，来源于早期胚胎的卵黄囊间充质干细胞有更强的自我更新能力和可塑性，且在胚胎发育过程中可分化为成血管细胞和造血干细胞，启动胚胎血管发生和造血组织发育。

Application of hemopoietic stem cells included hemopoietic stem cell transplantation and as target cells for gene therapy.

造血干细胞的应用包括造血干细胞移植和作为基因治疗的靶细胞。

Because the concentration and constitution of hemopoietic progenitor cells in peripheral blood differ from in bone marrow, the limitation of using CFU-GM dose to be reinfused as an indicator of hemopoietic reconstitution in PSCT shows more and more outstanding than in BMT.

但由于外周血干细胞含量及构成与骨髓不同，约为骨髓的1/10，所以关于外周血干细胞分析鉴定方法，如何分离收集足够数量的干细胞，以及采集干细胞的有效保存都是当今开展周围血干细胞移植的迫切需要解决及肯定的热点。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了