查询词典 hematopoietic

Purpose To study the protective effects of polysaccharides from lichen of parmelia tinctorium on hematopoietic function and DNA repair in radiation-injured mice.

目的 研究地衣类石花多糖对辐射损伤小鼠造血功能及DNA损伤的防护作用。

Methods Colony-forming unit of spleen, number of nucleated cells in bone marrow and spleen index were used to investigate the effect of polysaccharides at 50, 80 mg/kg from parmelia tinctorium intraperitoneal injection on hematopoietic function of mice irradiated with 137Cs γ-rays; DNA double-strand breaks were detected using alkaline single cell gel electrophoresis.

用内源性脾结节形成，骨髓有核细胞计数，脾脏指数观察石花多糖50，80 mg/kg腹腔注射对137 Csγ射线照射小鼠造血功能的影响；单细胞凝胶电泳技术检测小鼠淋巴细胞照射后的DNA双链断裂，观察给药后小鼠DNA损伤修复情况。

In Perciformes, chromaffin cells are distributed around the anterior and posterior cardinal veins and ducts of Cuvier; in Salmoniformes, around the posterior cardinal veins and in the hematopoietic tissue; and in G. affinis, around the ducts of Cuvier and posterior cardinal veins, while a few are visible also around the sinus venosus.

在鲈、铬细胞周围分布前后主教Cuvier脉及管道；在鲑鳟鱼类、周围静脉和后部主教在造血组织； G、慈、氩在地层的管道打通Cuvier后路主教，同时也有不少是围绕着静脉窦。

All HSCT patients were divided into aGVHD group ( 43 cases), thrombus group (TMA, HVOD, arterial and phlebothrombosis, 5cases) and infection group (31cases).1.2 Specimen collection and cytokines detectionThe serum specimen of all patients undergoing allogeneic hematopoietic stem cell transplant were collected once a week in the morning from preconditioning, 4 days after preconditioning until the time when they were discharged from hospital, 20 healthy adults were detected as normal controls.

根据并发症的发生情况诊为急性移植物抗宿主病组43例、血栓组(包括TMA、HVOD、动静脉血栓)5例和感染组31例。1.2标本收集与细胞因子指标检测清晨空腹静脉采集移植患者的外周血，采集时间为预处理前，预处理开始第4天，预处理结束后至出院之间各周外周血标本，每周一次。20名健康成人作为对照。

To sum up, we first put forward and proved the hypothesis that postembryonic pluripotent stem cells distribute in multiple human tissues, which may help explain the "stem cell plasticity", and that osteoblastic cells were a regulatory component of the hematopoietic stem cell niche by in vitro experiment.

在本论文的第四部分，我们借助体外造血发生模型，首次从另一个角度在体外证明了Scaden及Li等人的实验结果，并证明在造血&龛位&空间组成中，SCF和BMP-4是造血发生的重要调节因子。

The 1〓 generation of which is transfusion with mature cells, such as the whole blood and blood ingredient: the representative of the second generation is hematopoietic stem/progenitor cells transplantation, which can regraft normal hematopoiesis and immunity in a body with destroyed immunity and hematopoiesis by the self-renewal and multiple differentiation capacity of stem cells.

第一代细胞疗法是成熟血细胞的输注，如全血输注及成分输血等，对于纠正各种血细胞减少有明显疗效；第二代细胞疗法的代表是干细胞移植，指利用干细胞能够在体内自我更新和多向分化的能力在病态免疫和造血功能被摧毁的机体内重建正常的造血和免疫功能。

"Although a longer follow-up is required for assessment of the durability of response, the patient's course indicates that autologous hematopoietic stem cell transplantation may be a way to reinduce tolerance in patients with SLE," the authors write.

作者写道：「尽管仍需要更长时间的随访，来评价这种治疗效果的持久程度，但是患者的治疗过程提示，自身同源性血液干细胞的移植，可能是患有SLE患者再次唤起免疫耐受的一种方法。

Our results indicate that 1 NSC606985, at nanomolar level, can effectively induce apoptosis in AML cells NB4 and U937 and significantly inhibit the proliferation without cell death in breakpoint cluster region–Abelson murine leukemia kinase-carrying leukemic K562 cells; 2 At such low concentrations, this agent also significantly inhibits the clonogenic activity of hematopoietic progenitors from patients with AML; 3 For apoptosis induction, NSC606985 rapidly induces the proteolytic activation of protein kinase Cδ with loss of mitochondrial transmembrane potential and caspase-3 activation; 4 Co-treatment with rottlerin, a PKCδ-specific inhibitor, completely blocks NSC606985-induced mitochondrial m loss and caspase-3 activation, while the

结果显示：(1)纳摩尔浓度的NSC606985即可有效诱导AML细胞系NB4和U937细胞凋亡并显著抑制含有bcr-abl融合蛋白激酶的K562细胞的增殖；(2)低浓度的NSC606985也显著抑制来自AML病人骨髓的新鲜白血病细胞的克隆形成能力；(3)除了迅速诱导线粒体跨膜电位的崩塌及Caspase-3的活化外，NSC60698也导致蛋白激酶Cδ的水解激活；(4)PKCδ特异的抑制剂rottlerin能够完全抑制NSC606985诱导的线粒体跨膜电位的崩塌和Caspase-3的活化，而Caspase-3特异的抑制剂z-DEVD-fmk仅能部分削弱PKCδ的活化及细胞的凋亡；(5)以移植PML-RARα转基因小鼠产生的白血病细胞建立的模型研究了该化合物对白血病可能的治疗作用。

Objective To study the protective effects of polysaceharides of Tremella fueiformis on hematopoietic function in radiation-injured mice.

目的研究银耳多糖注射剂对辐射损伤小鼠造血功能的防护作用。

Objective To explore the protective effect of the polysaccharides of tricholoma matsutake on hematopoietic function of X-rays irradiated mice.

目的：探讨松茸多糖对辐射损伤小鼠造血功能的保护作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。