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Objective To investigate the alteration of vascular endothelial cells and circulation endothelial cells damage in acute-phase Patients with Coronary Heart DiseasConstruct technology platform of vascular endothelial cells damage, in order to provide new theory evidence and laboratory indicatrix of earlier-phase prophylaxis and diagnosis for nosogenesis、development、turnover of Coronary Heart Disease Methods 65 acute-phase Patients with Coronary Heart Disease of preparing for operation of heart...

目的探讨冠心病患者急性期血管内皮细胞、循环内皮细胞损伤的特点,构建检测内皮细胞损伤的技术平台,为冠心病的发生、发展、转归,甚至早期预防及诊断提供新的理论依据和实验室指标。

Lungs of conclusion children heart turns stream operation of orthoptic congenital heart disease can bring about the hurried inflammation He Kangyan such as TNF-α, IL-6, IL-8, IL-10, CRP inside the heart of disease medium release, turn in heart lungs the likelihood in shedding the systemic inflammation that cause to react produces main effect.

结论小儿心肺转流心内直视先天性心脏病手术可导致TNF-α、IL-6、IL-8、IL-10、CRP等促炎症和抗炎症介质的释放,在心肺转流诱发的全身炎症反应中可能发挥重要功能。

This academy sheds motivation to monitor appearance to detect with blood of impedance type heart patient of coronary heart disease 186, evaluate its heart function, report result analysis as follows now. 1.1 average data choose 1 data and method 2007 patient of 1~5 month be in hospital 186, male 91, female 95, age 41~89 year old, all be patient of coronary heart disease, among them instability angina patient 49, dead patient of stalk of acute cardiac muscle 24, amalgamative hypertension is ill 66, amalgamative diabetic 17, amalgamative heart function is not complete class of Ⅱ~Ⅲ person 30. The BioZ.com blood that 1.2 methods and measure choose company of American CardioDyamics international to produce is kinetic tutelar appearance, entire case all is be admitted to hospital that day or morrow detects, 25 patients treat 1 week hind to check again.

本院用阻抗式心脏血流动力监测仪检测冠心病患者186例,评估其心功能,现将结果分析报告如下。1资料和方法1.1一般资料选择2007年1~5月住院患者186例,男91例,女95例,年龄41~89岁,均为冠心病患者,其中不稳定性心绞痛患者49例,急性心肌梗死患者24例,合并高血压病66例,合并糖尿病17例,合并心功能不全Ⅱ~Ⅲ级者30例。1.2方法和步骤选用美国CardioDyamics国际公司生产的BioZ.com血液动力学监护仪,全部病例均为入院当天或次日检测,有25例患者治疗1周后再次复查。

Cardiac hypertrophy is one of adaptive responses of the heart to a variety of pathological stimuli, including hypertension, myocardial infarction, congenital heart disease, heart valvula disease, and perturbations in sarcomeric function due to altered expression or mutations of contractile proteins. Increase in wall tension and hormonal stimuli are thought to directly activate various membrane-bound receptors and signal transduction cascade within cardiomyocytes resulting in the activation of immediate early genes and responsive genes such as c-jun, c-fos, c-myc, egr-1, ANF, BNP. Then the expression of construction proteins such as MLC-1, skeletal α-actin was unregulated.

中文题名hhlim基因的表达调节及其与心肌细胞肥大发生之间的关系副题名外文题名 hhlim gene expression regulation and its role in development of cardiomyocyte hypertrophy 论文作者郑斌导师温进坤韩梅学科专业生物化学与分子生物学研究领域\研究方向学位级别博士学位授予单位河北医科大学学位授予日期2003 论文页码总数106页关键词心肌细胞肥大基因表达心肌肥厚 hhlim基因馆藏号BSLW /2003 /R542.2 /33 心肌细胞肥大是高血压、心脏瓣膜病、急性心肌梗塞及先天性心脏病等临床常见疾病的一种并发症,是心肌细胞对多种病理刺激的一种适应性反应。

Companion of accentuation of the illness 2 years ago is oedema of discontinuous double lower limbs, nightly clonic breath is difficult, colour of electrocardiogram, heart exceeds an examination to diagnose for " coronary heart disease, heart expands, atrium is vibratile, hypertensive disease 3 class ", the illness after outer courtyard gives step-down, strong heart treatment improves, grant for a long time to block Tuopuli 25mg is daily 3, alvine dissolve aspirin 75mg is daily 1, ester 10mg of Shan Li of nitric acid different is daily take 3 times, the illness is stable.

因活动后心慌、气促10年,伴反复抽搐,伴短暂意识丧失11个月,复发1天入院。10年前出现体力活动后心慌、气促,在当地医院诊断为"冠心病",治疗情况不详。2年前病情加重伴间断双下肢水肿、夜间阵发性呼吸困难,心电图、心脏彩超检查诊断为"冠心病、心脏扩大、心房颤抖,高血压病3级",在外院给予降压、强心治疗后病情好转,长期予卡托普利25mg每日3次、肠溶阿司匹林75mg每日1次、硝酸异山梨酯10mg每日3次服用,病情稳定。

Methods Apply xanthine oxidase and third dialdehyde.To determine the serum LPO,SOD,GSH-PX and CAT level in 106 cases of coronary heart disease including 29 cases of acute myocardial infarction,16 cases of coronarism and 61 cases of previously suffered coronary heart disease,and in 31 cases of cerebrovascular disease as well as in 65 cases of healthy persons.

应用黄嘌呤氧化酶法和丙二醛法,对106例冠心病,其中包括29例心肌梗塞,16例心绞痛,61例陈旧性冠心病,31例脑血管病和65例健康人,做血清LPO和SOD,GSH-PX,CAT水平的监测。

Coronary heart disease, also called coronary artery disease and atherosclerotic heart disease, is the end result of the accumulation of atheromatous plaques within the walls of the arteries that supply the myocardium.

冠心病,也被称为冠动脉疾病和心脏冠动脉硬化疾病,主要原因是供给心肌动脉的血管壁上粉瘤的积聚。

Companion of accentuation of the illness 2 years ago is oedema of discontinuous double lower limbs, nightly clonic breath is difficult, colour of electrocardiogram, heart exceeds an examination to diagnose for " coronary heart disease, heart expands, atrium is vibratile, hypertensive disease 3 class ", the illness after outer courtyard gives step-down, strong heart treatment improves, grant for a long time to block Tuopuli 25mg is daily 3, alvine dissolve aspirin 75mg is daily 1, ester 10mg of Shan Li of nitric acid different is daily take 3 times, the illness is stable.

因活动后心慌、气促10年,伴反复抽搐,伴短暂意识丧失11个月,复发1天入院。10年前出现体力活动后心慌、气促,在当地医院诊断为&冠心病&,治疗情况不详。2年前病情加重伴间断双下肢水肿、夜间阵发性呼吸困难,心电图、心脏彩超检查诊断为&冠心病、心脏扩大、心房颤抖,高血压病3级&,在外院给予降压、强心治疗后病情好转,长期予卡托普利25mg每日3次、肠溶阿司匹林75mg每日1次、硝酸异山梨酯10mg每日3次服用,病情稳定。

Perhaps noise pollution has nothing in your heart,as it doesn't affect you yet,or you can't take care to it.but once you suffered it,it will impressed by its affects.people who work in the condition have deep impression.long-term noise pollution can lead to insomnolence、giddiness、headache,evern more,some will suffer from coronary heart disease、heart muscles disease and so on.this is medical theroy,not lie.

噪声在您的心里也许并没有什么,那是因为您还没有受到它的伤害,或者是还没有注意到它,但当您注意到它是,就再也无法忘记了,长期处于噪声污染中的人是深有体会的,因为长期的噪声污染可以让一位很健康的人失眠,头晕,头痛,严重的会得冠心病,心肌梗岁等,这是医学道理,不是随便说出来的。

the coronary heart disease exist the insulin resistance, hyperinsulinism and lipin metabolism abnormity, they are all the dangerous factor which the coronary heart disease occurs, the insulin resist and the coronary heart disease clinical symptom serious degree are related.

冠心病存在胰岛素抵抗、高胰岛素血症及脂质代谢的异常,它们都是冠心病发生的危险因素,胰岛素抵抗与冠心病临床症状的严重程度相关。关键词:冠心病;胰岛素抵抗;血脂

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