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Forty female KM mice were classified into four groups by weight: control group, carnosine group, CDDP modal group and carnosine prevention group.

雌性昆明小鼠按体重分成4组，分别为正常对照组，肌肽对照组，顺铂化疗模型组和肌肽保护组。

Results: IL-8 protein was located in the epithelium of viii. The expression of IL-8 was significantly increased in RSA group than that in the control group. Positive IL-8 cells was shown in decidua of RSA group, and its IL-8 level was higher than that in the control group. By hematoxylin-eosin staining. trophoblastic layer was found to get thinner, cells of trophoblastic layer denatured or necrotized, and turned acidophily, and the fibration of villous axis increased in RSA; decidual cells lost connection, a part of decidual cells appeared cytoclasis and turned more acidophilic, and nuclei disappeared in RSA.

结果：在绒毛组织中，IL-8蛋白定位于绒毛上皮细胞的细胞质内，且病例组的表达明显高于对照组；在蜕膜组织中；病例组蜕膜细胞的胞质内可见IL-8蛋白表达，且高于对照组；H-E染色可见病例组绒毛组织的滋养层变薄，细胞变性甚至坏死、嗜酸性增强，绒毛中轴纤维化程度增强；蜕膜组织中蜕膜细胞失去细胞间连接，部分蜕膜细胞解体、核消失。

The model of thyroid hormone-induced diarrheic rats was prepared and interfered by low, medium and high dose of Asi-antidiarrheal capsule and berberine. Immunohistochemistry was used to detect the population, ratio of degranulation, area, perimeter, equivalent diameter and cyclo-dimension of the MC in duodenum mucosa of control group, model group, berberine group and Asi-antidiarrheal capsule group.

运用阿是止泻胶囊低、中、高剂量及黄连素对其干预，采用免疫组化技术测定对照组、模型组、黄连素组、阿是止泻胶囊低、中、高剂量组大鼠十二指肠黏膜MC数量、脱颗粒比率、面积、周长、等效直径及圆形度。

Sugar water choosed degree have no significant change. It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进，降低慢性应激所致IBS模型大鼠的内脏敏感性，显著减少了IBS模型大鼠的排便数量，从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的：探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进，降低慢性应激所致IBS模型大鼠的内脏敏感性，显著减少了IBS模型大鼠的排便数量，从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的：探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环(来源：49ABC论文网www.abclunwen.com)烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

It may means that Iridoids composition of Valeriana jatamansi Jones doesn\'t regulate the TPH1 transcription expression.3.4 Effection of Iridoids composition of Valeriana jatamansi Jones on SP and VIP of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

造模后，中枢5-HT呈现降低趋势，这可能是导致动物出现活动能力下降和兴趣缺失的原因之一，蜘蛛香环烯醚萜可以增加下丘脑、海马和杏仁核中5-HT含量，推断蜘蛛香环烯醚萜可通过干预中枢的5-HT通路来改善IBS精神症状。3.2蜘蛛香环烯醚萜对胃肠激素的影响目的：探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠SP和VIP的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Methods A total of 60 male rats were randomly assigned into normal group,model group,drug control group,low -dose(17.5 mg·kg-1),mid-dose (35.0 mg·kg-1) and high -dose QLS (70.0 mg·kg-1) groups,10 rats in each group. White cell count,lecithin corpuscle density in prostatic fluid,prostate weight and prostate index were observed respectively after acute rat models were made by injecting 1 % carrageenan in th e seminal vesicle of prostate gland notopodium.

Wistar大鼠按体重区组随机分组方法分为空白对照组、模型组、阳性对照组及QLS低（17.5 mg·kg-1）、中（35.0 mg·kg-1）、高剂量组（70.0 mg·kg-1），每组10只，分别于前列腺背叶的精囊腺注入1 %角叉菜胶生理盐水溶液，制作大鼠非细菌性前列腺炎模型，观察测定前列腺液中白细胞数和卵磷脂小体密度、前列腺重量、前列腺指数。

The Tongfuxingshen liquid proctoclysis can promote the patients in unconscious state to conscious state, and improve the degree of coma and the scores of nervous functional defects,To observe the expression of HSP70, HO-1mRNA and the Cerebral vessels permeability, encephaledema in rat brain after experimental haemorrhagic stroke. Hemorrhagic stroke Sprague Dawley rat model was made by injecting collagenase type Ⅶ and hepathrom stereotaxically, Rats were randomly divided into fake operation group, model group and enema group, take orally group, in three time point (3 days, 5 days, 7 days) we observed the change of cerebral vessels permeability, encephaledema and HSP70 immunohistochemistry, HO-1mRNA hybridization in situ.

结果表明，通腑醒神液直肠滴注较灌胃起效快，能尽快促使昏迷患者神志清醒，意识清醒时间平均为4.94天，而灌胃组为6.9天，经统计学处理有极显著性差异；明显改善患者的昏迷程度，第8天治疗组Glasgow-Pittsburgh昏迷评分值平均为29.39分，对照组为26.60分，经统计学处理有极显著性差异；治疗后14天临床疗效比较，通腑醒神液直肠滴注组总显效为54.84%，总有效率为80.65%，而灌胃组总显效为43.33%，总有效率为66.67%，经统计学处理无差异性，可能为样本量过少有关，尚需进一步增加样本量评估。

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Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。