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The Underwriter may terminate its commitment under the Underwriting Agreement at any time prior to the Latest Time for Termination if: there shall develop, occur, exist or come into effect: any new law or regulation or any change in existing laws or regulations or any change in the interpretation or application thereof by any court or other competent authority in Hong Kong or any other place in which any member of the Group conducts or carries on business; or any event or series of events resulting or likely to result in any change in local, national or international financial, political, military, industrial, economic or market conditions; or any change in the conditions of local, national or international securities markets (including but without limitation, the imposition of any moratorium, suspension or restriction on trading in securities generally on the Stock Exchange due to exceptional financial circumstances or otherwise); or any change or development involving a prospective change in Hong Kong taxation or exchange control which will or may affect the Group or a proportion of the existing Shareholders of the Company in their capacity as such, which, in the reasonable opinion of the Underwriter:(1) is or will or is likely to have a material adverse effect on the business or financial condition of the Group as a whole or the Rights Issue; or (2) has or will have or is likely to have a material adverse effect on the success of the Rights Issue or the level of Rights Shares taken up; or (3) makes it inadvisable or inexpedient for the Company to proceed with the Rights Issue; or there comes to the notice of the Underwriter: any matter or event showing any of the representations, warranties and undertakings made by PIL and the Company was, when given, untrue or misleading or as having been breached in any respect; or any breach by any of the other parties to the Underwriting Agreement of any of their respective obligations or undertakings under the Underwriting Agreement or under any of the PIL Letter of Undertaking, Option Undertakings or the Sub-underwriting Letter, then and in any such case the Underwriter may, upon giving notice to the Company and PIL, terminate the Underwriting Agreement with immediate effect.

倘发生下列事件，包销商可于最后终止时间前任何时间终止其根据包销协议之责任：以下情况将会出现、发生、存在或生效：香港或本集团任何成员公司经营或从事业务所在任何其他地方之法院或其他主管机关颁布任何新法律或法规，或更改现行法律或法规，或有关法律或法规之诠释或应用有变；或发生任何事件或连串事件导致或可能导致本地、国家或国际金融、政治、军事、工业、经济或市况有变；或本地、国家或国际证券市场之状况有变（包括但不限于因特殊金融状况或其他原因而暂时禁止、暂停或限制港交所之整体证券交易）；或香港税务或外汇管制有变或出现可能导致变动之事态发展，而将会或可能对本集团或本公司部份现有股东产生影响，而包销商合理认为上述情况：(1)会或将会或可能会对本集团整体之业务或财务状况或供股有重大不利影响；或(2)经已或将会或可能会对供股之成功或供股股份之认购数量有重大不利影响；或(3)令本公司进行供股变得不智或不宜时；或包销商得悉：任何事情或事件显示太平船务及本公司所作出之任何陈述、保证及承诺于作出时在任何方面属失实或构成误导或遭违反；或包销协议之任何其他订约方违反彼等各自根据包销协议或任何太平船务承诺函、购股权承诺或分包销函件之任何责任或承诺，而在此情况下，包销商可向本公司及太平船务发出通知即时终止包销协议。

A treatment group of 30 patients with acute cerebral infarction was treated by intradermal point injection, an acupuncture group of 30 patients, by acupuncture and a Western drug group of 30 patients, by routine Western medical treatment.

治疗组 30例采用穴位皮内注射"血栓通"注射液治疗急性脑梗死，针刺组 30例采用针刺治疗，西药组 30例采用西医常规治疗。

METHODS: The models of abdominal aorta transplantation were made with micro-surgery in rats. The recipients were divided into three groups: allograft control group, atorvastatin-treated group and isograft control group. Vascular intimal thickness in all of the groups was observed by histological examination. The expression of proliferation cell nuclear antigenl and α-smooth muscle actin were determined by immunohistochemistry. The content of nitric oxide was measured by nitrate reductase chromatometry.

建立大鼠腹主动脉移植慢性排斥反应模型，分为3组：异系移植对照组、异系移植治疗组和同系移植组，60d后对移植动脉行病理组织学检测，观察移植动脉内膜增生程度；并行免疫组织化学染色，检测移植动脉增殖细胞核抗原和平滑肌肌动蛋白的表达情况，行硝酸还原酶比色法测定移植动脉组织NO的含量。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. The n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. Then 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. The n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶治疗组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数分析来评估神经元的情况。

METHODS: Sixty healthy Sprague-Dawley rats were randomly divided into 3 groups: 6 rats in normal control group, 6 rats in EGb treating normal IOP group, and the other 48 rats were established chronic high IOP models of rats by cauterizing two episcleral veins. n 30 rats satisfying experimental level were selected and randomly divided into five groups: 6 rats in physiological brine treating group, and the other 24 rats were divided into four experimental groups according to the dose of EGb: group A, EGb 50mg/; group B, EGb 100mg/; group C, EGb 150mg/; and group D EGb 200mg/. After the treating time of 1 month, the rats were sacrificed on schedule. Flat preparation of whole retinaes was stained distinctively and neuron counting in retinal ganglion cell layer from both eyes of each rat were performed to evaluate neuron situation.

取健康SD大鼠60只，正常对照组和正常银杏叶组各6只，其余48只采用烧烙法，烙闭大鼠左眼2条浅层巩膜静脉，制作大鼠持续性高眼压模型，从中选出眼压稳定在实验要求水平的大鼠30只，随机分为生理盐水组，治疗A组（每日EGb 50mg/kg）、治疗B 组（每日EGb 100mg/kg）、治疗C 组（每日EGb 150mg/kg）、治疗D 组（每日EGb 200mg/kg），治疗时间为1mo，处死大鼠后做视网膜全层铺片，对RGCL神经元做特异性染色后行神经元计数来评估神经元的情况。

Materials and Methods: According to authoritative clinical diagnosis standards and evaluation standards, 90 cases of outpatients and inpatients were selected as the research subjects. These patients of H.pylori associated alimentary disease all failed on routine triple therapy and belonged to deficiency-cold of spleen and gaster, damp-heat of spleen and gaster as well as stagnant blood of gaster. 90 cases were divided into three groups stochastically. Among these patients, 30 cases were served as contrast groupⅠ treated by "Omeprazole, Clarithromycin, Metronidazole", 30 cases were served as contrast groupⅡtreated by "Omeprazole, Levofloxacin, Ornidazole", the other 30 cases were served as observation group treated by "Qingyou Soup" associated with above-mentioned routine medicines. The period of treatment of all three groups was 2 weeks.

资料与方法：根据2007年《第三次全国Hp共识会议》制定的Hp感染临床诊断标准、根除标准，以及2002年《中药新药临床研究指导原则》的病例选择标准、中医辨证标准、临床疗效判断标准，选择经西医常规三联疗法根除失败的Hp感染相关消化疾病，且中医辨证属脾胃虚寒、脾胃湿热、胃络瘀血证的门诊和住院患者90例，随机分为对照组Ⅰ、对照组Ⅱ、治疗组，对照组Ⅰ30例予常规三联药物&奥美拉唑、克拉霉素、甲硝唑&治疗，对照组Ⅱ30例予新三联药物&奥美拉唑、左氧氟沙星、奥硝唑&治疗，治疗组30例予中药方剂&清幽汤&联合上述常规三联药物治疗，三组均以1周为一个疗程，共治疗2个疗程。

Methods: the present study improved isolation of LDL, undertook one-step of density gradient centrifugation, generate E-LDL by treatment LDL with multiple enzymes, direct fluorescent label CRP and LDL, and investigate whether CRP play as intermedial mediator in atherosclerosis. Experiment consists of 8 groups: control group, N-LDL group, ox-LDL group, E-LDL group, CRP+N-LDL group, CRP+ox-LDL group, CRP+E-LDL group.

本研究参考文献改进LDL提取方法，通过一次性密度梯度超速离心，分离LDL，并且通过复合酶处理以及铜离子氧化法分别生成E-LDL和ox-LDL，并直接对CRP及LDL进行荧光标记，通过与内皮细胞共孵育，利用荧光显微镜检测CRP及LDL与内皮细胞结合，实验分为8组：空白对照组、CRP组、N-LDL组、ox-LDL组、E-LDL组、CRP+N-LDL组、CRP+ox-LDL组、CRP+E-LDL组。

RESULTS: FGFR1-positive chondrocytes were abundant in the maturative layer and hypertrophic layer, but only few FGFR1-positive chondrocytes were found in the proliferative layer. In the control group, the expression of FGFR1 increased from 6-week-old to 10-week-old rats, and then decreased and went stable. In both young and adult group, the expression of FGFR1 in the experimental group was significantly lower at 4, 6 weeks and higher at 8 weeks than that in the control group, especially in the young group (P.05). But no difference was found between the experimental group and the control group at 2 weeks in both groups. CONCLUSION: FGFR1 may play an important role in the remodling of condylar cartilage induced by occlusal disorders.

结果：FGFR1主要表达在大鼠髁突软骨过渡层和肥大层，增殖层很少；正常组大鼠髁突软骨从6周龄到10周龄FGFR1表达逐渐增强，10周龄后降低，并保持在一个稳定水平；成年组和幼年组实验4、6周时FGFR1的表达均显著低于对照组，实验8周时的表达高于对照组(P.05)，幼年组尤为明显，实验2周组与对照组无显著差异。

When trading exclusives with media for positive stories, make sure the deal stays

和媒体签订的协议只有总编知道就好了，没必要通知每一个员工

We are nine and fifty-nine, and one of us is good at guessing plots—not me!

我们两人中有一个很擅长猜情节——不是我！