查询词典 graft

Methods Four patients with chronic myeloblastic leukemia and 4 with acute myeloid leukemia received allo-BMT with graft from 1 - 3 HLA-mismatched related donors.

方法4例慢性粒细胞白血病和4例急性髓性白血病患者接受人类白细胞抗原1-3个位点不相合骨髓移植，用阿糖胞苷、环磷酰胺和全身照射或马利兰进行预处理。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

In this review data on the use of rituximab is presented from 92 studies involving 1197 patients with the following diseases: systemic lupus erythematosus, idiopathic thrombocytopenic purpura, anti-neutrophil cytoplasmic antibody associated vasculitis, Grave's disease, autoimmune hemolytic anemia, pemphigus vulgaris, hemophilia A, cold agglutinin disease, Sjogren's syndrome, graft vs. host disease, thrombotic thrombocytopenic purpura, cryoglobulinemia, IgM mediated neuropathy, multiple sclerosis, neuromyelitis optica, idiopathic membranous nephropathy, dermatomyositis, and opsoclonus myoclonus.

本综述资料总结了92项共1197例患者应用利妥昔的研究，包括系统性红斑狼疮、特发性血栓性血小板减少性紫癜，抗中性粒细胞抗体相关性血管炎、甲状腺功能亢进、自身免疫性溶血性贫血、寻常型天疱疮、甲型血友病、冷凝集素病、干燥综合征、移植抗宿主疾病、血栓性血小板减少性紫癜、IgM介导性神经病、多发性硬化、视神经脊髓炎、特发性膜性肾病、皮肌炎和眼肌阵挛性肌阵挛。

And 16 caes were operated on,including neurolysis,repaired by direct suture,nerve graft and nerve transposition.

16例行手术治疗，治疗方法包括：神经松解，神经吻合，神经移植，神经移位。

Objective To explore the nerve repair disparity of dobule end-to-side neurorrhaphy,end-to-side neurorrhaphy and nerve graft with vessels and to discuss the possibilities of clinical application.

目的 比较神经双端侧吻合、端侧吻合与神经移植三种术式修复神经缺损的能力差异，进一步探讨神经双端侧吻合术式的临床应用可行性，为临床神经缺损的修复提供新的术式及其理论根据。

This safe and easy method shortens the hospital stay and reduces the risk of graft extrusion and complications associated with the use of nonabsorbable devices.

结论∶与利用不能吸收的装置相比，这是一种安全有效的简便治疗方法，缩短了住院时间，减少了移植物被挤出的风险和其他并发症。

Intervention: In group 1, 31 patients were treated with either a Neer or Aequalis shoulder prosthesis using nonabsorbable sutures and no bone graft for the reattachment of the tuberosities.

干预：第1组，31名病人接受Neer 或Aequalis人工肩关节置换术治疗，使用非吸收性缝线和非植骨肱骨结节复位法。

However, nonadherence is common, jeopardizing graft survival.

然而，患者中不坚持药物治疗的情况也很常见，这样常会危及移植物的存活。

Criterion for graft patence was contrast opacification on at least two noncontiguous levels and time-density curve morphologically similar to that of the aorta.

UFCT是一种很有价值，少创的评价冠状动脉搭桥血管的方法，检查技术成功率高，绝大多数病例扫描后可分析判定搭桥血管通畅与否。

Many osteoid were formed around metal surface and bone graft remodeling was active in 1 month as shown by nondecalcified section.

大体观察可见6个月时三翼臼植骨区表面与正常骨表面相仿，界限不清，可见三翼臼的翼板被骨组织包埋。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。