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The treatment group was given Qizhengxiaotong Emplastrum(0.75 g/kg),and the model group and blank group were given normal saline solution(0.5 mL/each)externally for 5 days on 10th day after the establishment of ...
末次给药后测量各组小鼠的痛行为,包括机械性痛觉超敏和热刺激痛觉过敏;将小鼠股骨进行X线摄片,影像学评估骨破坏;用免疫组化法检测各组局灶皮肤组织肿瘤坏死因子α、内皮素-1(ET-1)、白介素-1β(IL-1β)水平及脊髓后角P物质受体、c-fos及GFAP阳性反应神经元的表达。
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Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan (the average body weight was 25~30 kg)were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P<001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P<001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P<001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P<001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs
目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系,探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只,平均体重25~30 kg。随机分为3组:正常对照组10只,模型组10只(球囊内膜剥脱加高胆固醇饮食),治疗组10只(球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d)。结果兔髂动脉造影、血管病理图像分析检测结果:①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比,各组之间有显著性差异(P<001)。②免疫组化分析:模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组(P<001);复方丹参滴丸组MMP2、MMP9的表达低于模型组,而TIMP1、TIMP2的表达高于模型组;TIMP1/MMP2、TIMP2/MMP9明显增加,差异有显著性(P<001)。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896,P<001)。结论 MMP和TIMP在再狭窄形成中起重要作用;复方丹参滴丸能够明显抑制血管损伤后的内膜增生,可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生,而减少内膜的增生。
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Enhydra DODS - DODS is a tool which, for the given doml file, can generate SQL script files for creating tables and/or java code for data objects described in the given doml file.
Enhydra DODS是为处理doml文件提供的一个工具,可以为在给定的doml文件中描述的数据对象生成SQL脚本来创建表和Java代码。
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Most of the literature on bank runs takes the asset side of the bank activities as given and assumes that the bank's returns are determined by an exogenously given production function.
大多数有关银行挤兑的文献将银行经营的资产部分作为给定的,并假定银行收益是由外生给定的生产函数决定的。
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The classical Mirrlees tax model is a particular example of this essay when the state is given. But there are minute differences that Mirrlees has taken the public spending as variables given exogenously and instead I regard it as endogenous variables that need be optimized and selected by government.
经典的Mirrlees税收模型是本文在给定状态下的一个特例,略微不同的是,Mirrlees将公共商品的花费作为外生给定的,而在这里,我们把它作为由政府选择需要优化的内生变量。
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Methods 100 patients were randomly assigned into two groups. Fifty cases in treatment group were given conventional treatment combined with "Fagopyrum Cymosum Decoction" and another 50 cases in control group were given conventional treatment combined with ambroxol.
100例COPD急性加重期病例分为治疗组和对照组,均给予氧疗、抗生素等西医常规治疗,治疗组给予金荞麦水剂口服,对照组给予氨溴索口服。
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82 patients diagnosed as having RVVC were given fluconazole and mycostain until their fungological detection results were negative.They were then randomly divided into 2 groups: the treatment group was given live preparation of Lactobacillus,while the control group continued the above anti-fungal consolidation treatment for 6 months.
方法确诊为RVVC的患者82例,用氟康唑加制霉菌素治疗至真菌学转阴后,随机分成2组:治疗组用上述抗真菌巩固后采用阴道乳酸杆菌活菌制剂治疗;对照组连续进行6个月的抗真菌巩固治疗。
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The concept of harmonic control between two systems is presented. Necessary and sufficient conditions are given for harmonical stabilization of two systems. These results can be generalized to harmonic stability problems for more than two systems. Examples are given to illustrate the results.
摘要提出了两个系统协调控制的概念,主要研究了不同系统间的互助合作问题,给出两个系统间可协调稳定的充要条件及构造协调控制律的算法,并举例说明了所给结果的有效性,这些结果都可以向多系统协调稳定问题推广。
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The concept of harmonic control between two systems is presented. Necessary and sufficient conditions are given for harmonical stabilization of two systems. These results can be generalized to harmonic stability problems for more than two systems. Examples are given to illustrate the results.
提出了两个系统协调控制的概念,主要研究了不同系统间的互助合作问题,给出两个系统间可协调稳定的充要条件及构造协调控制律的算法,并举例说明了所给结果的有效性,这些结果都可以向多系统协调稳定问题推广。
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In this paper, the standard accelerated hygrothermal aging spectrum for military aircraft composite structures is given based on the domestic climatic environment and the developing aircraft properties, and the aging effects for our composite material system are systematically studied, and the conclusion for guiding and modifying the structure design are given.
本文根据我国气候环境和在研型号性能,编制了适用于军机复合材料结构的标准加速湿热老化谱,并系统研究了国产材料体系的老化效应,得出了指导和修改结构设计的有益结论。
- 相关中文对照歌词
- Given The Dog A Bone
- Given A Chance
- All That I've Given Away
- Nothing, Save The Power They're Given
- Given Half The Chance
- Given It All
- On Any Given Night
- On Any Given Day
- All You've Given
- Blessed, Broken & Given
- 推荐网络例句
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In the United States, chronic alcoholism and hepatitis C are the most common ones.
在美国,慢性酒精中毒,肝炎是最常见的。
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If you have any questions, you can contact me anytime.
如果有任何问题,你可以随时联系我。
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Very pretty, but the airport looks more fascinating The other party wisecracked.
很漂亮,不过停机坪更迷人。那人俏皮地答道。