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Methods 4-Hydroxy- benzonitrile was treated with sodium hydrogen sulfide and anhydrous magnesium chloride in dimethyl formamide to give thioamide, which was then directly cyclized with ethyl 2-chloroacetoacetate without separation to give ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(2) in one-pot; then 2 was formylated with Duff reaction adopting hexamethylenetetramine in trifluoroacetic acid to give ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate(3); finally, the target compound was obtained by the treatment of 3 with hydroxylamine hydrochloride and sodium formate in formic acid.
采用"一勺烩"方法,以4-羟基苯甲腈为起始原料,首先与硫氢化钠和无水氯化镁在N,N-二甲基甲酰胺中反应,所得中间体不经分离,直接加入2-氯乙酰乙酸乙酯进行环合反应,得到2-(4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯(2);然后通过六亚甲基四胺/三氟乙酸进行Duff反应,得到2-(3-甲酰基-4-羟基)苯基-4-甲基-5-噻唑甲酸乙酯(3);再经盐酸羟胺/甲酸/甲酸钠体系脱水得到目标化合物。
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"There's been many studies that have shown that things like citronella , tea-tree oil, eucalyptus oil give very, very poor protection," Doggett says. Some of them only give protection for five minutes and they give a false sense of security to people ...
昆虫学家Stephen Doggett说,有许多研究表明香茅、茶树油、桉树油等只能提供很小的保护,它们中的一些只提供大约5分钟的保护,但是它们给人们一种错误的安全感。
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Keep on struggling on Don't give up the fight We're sick and tired of your ism and skism game Die and go to heaven in Jesus' name, Lord We know when we understand Almighty God is a living man You can fool some people sometimes But you can't fool all the people all the time So now we see the light We gonna stand up for our right So you'd better get up, stand up, stand up for your right Get Up, Stand Up, don't give up the fight Get Up, Stand Up, stand up for your right Get Up, Stand Up, don't give up the fight....
继续就不要放弃斗争,我们正在生病,你的ISM和skism游戏累了模具和去到耶稣的名字天堂挣扎,当我们知道上帝全能的上帝是我们understand一个活人可以欺骗一些人You有时但你不能欺骗所有的人所有的时间,所以现在我们看到了光明我们要去站起来为我们的权利,因此,你最好站起来,站起来,捍卫你的权利站起来,站起来,不要放弃斗争起来,站起来,捍卫你的权利起床了起来,站起来,不要放弃这场斗争。。。。
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If I had the power to give humor to the nation I would not give them drollery, for that is impractical; I would not give them wit, for that is aristocratic, and many minds cannot grasp it; but I would be contented to deal out fun, which has no intellectual element, no subtlety, belongs to old and young, educated and uneducated alike, and is the natural form of the humor of the Englishman.
如果我有权给予此民族幽默的特质,那么我就不给予他们诙谐的本领,因为那不切实际;我也不给予他们风趣的风格,因为那过于贵族派头,以致多数人无法理解;我要心满意足地给予他们逗乐儿的本事,即不分智力高下,没有隐晦曲折,无论老少或受教育与否都能享受的英国式的自然幽默。
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If I had the power to give humour to the na-tions I would not give them drollery,for that isimpractical;I would not give them wit,for that isaristocratic,and many minds cannot grasp it;but Iwould be contented to deal out fun,which has nointellectual element,no subtlety,belongs to oldand young,educated and uneducated alike,and isthe natural form of the humour of the Englishman.
如果我有权给予各民族幽默,那么我不给予他们解嘲,因为那不切实际;也不给予他们风趣,因为那过于贵族派头,以致多数人无法理解;我要心满意足地给予他们逗乐儿,即不分智力高下,没有隐晦曲折,无论老少或受教育与否都能享受的英国式的自然幽默。
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Turn away from; give up同义词:foreswear, renounce, relinquish5. give up in the face of defeat of lacking hope; admit defeat同义词:drop out, give up, fall by the wayside, drop by the wayside, throw in, throw in the towel, chuck up the sponge
本站所收集信息资料为网络转载版权属各作者并已著明作者旨在资源共享、交流、学习之用,请勿用于商业用途,本站并不保证所有信息、文本、图形、链接及其它内容的绝对准确性和完整性,故仅供访问者参照使用。
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Turn away from; give up同义词:foreswear, renounce, quit, relinquish5. give up in the face of defeat of lacking hope; admit defeat同义词:drop out, give up, fall by the wayside, drop by the wayside, throw in, throw in the towel, quit, chuck up the sponge
本站所收集信息资料为网络转载版权属各作者并已著明作者旨在资源共享、交流、学习之用,请勿用于商业用途,本站并不保证所有信息、文本、图形、链接及其它内容的绝对准确性和完整性,故仅供访问者参照使用。
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Paid or payable to any one and not given or agreed to give and shall not give or agrree to give to any one within or outside Pakistan either directly or indirectly through any natural or juridical person, including its affiliate,,agent,associate,broker,consultant,director,promoter,shareholder,sponsor or susidiary,any commission,gratification,bribe,finder's fee or kickback,whether described as consultation fee or otherwise,with the object of obtaining or inducing the procurement of a contract,right,interest,privilege or other obligation or benefit in whatsoever form from GoP,except that which has been expressly declared pursuant hereto.
在不限制前述的一般,代表和认股权证,它已完全宣布经纪佣金,手续费等已付或应付的任何一个,而不是给予或同意,不得给予或给予agrree任何一个内部或外部巴基斯坦直接或间接通过任何自然人或法人,包括其子公司,代理人,准,经纪人,顾问,主任,推动者,股东,赞助或susidiary ,任何佣金,满足,贿赂,查找费或回扣,无论是描述为协商收费或其他形式的,目的是获取或诱导采购合同,权利,利益,特权或其他义务或利益的任何形式来自共和党,但已明确宣布,根据函。
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Http://www.zshare.net/audio/671213750036217a/ Yungztuh 403 tha realest on da scene triple beam only seventeen yungin dont give phuc lazz it down foh ma homies on da streets nay mean fake ass snake be ducking around running around like their in a phuc'in track meet so im comming back wid da fourty five leave these hataz 6 feet deep and still alive ima keep it live yo foh son young asian cat wid da gun, dis 187 shiet has just begun want beef 2 sicc wid dis leave ya deseased rest in piss on avenue corner of your block straight banging dis set till midnight clock batttle field got da caps peeled back on side be chillin makin these tracks makin these paper stacks rising these tax on these foos young and dangerous u see cant phuc wid a asian g burry your carcus in a cemetary bettah know yo place laz it down 403 soaked up on hennessy, give ya hataz a taste give me face or ya whole life will be a waste...
http://www.zshare.net/audio/671213750036217a/ Yungztuh 403三重塔realest梁大舞台上只有17 yungin不要给伏lazz下来文物之友达街道马兄弟,在NaY平均假像蛇屁股回避他们的周围到处乱跑在phuc'in田径运动会等即时通讯回来妇女参与发展达45给这些hataz 6 英尺深,仍然活着的IMA保持住哟亚洲青少年文物之友子猫妇女参与发展的大枪,解散187 shiet刚开始要牛肉二上咨妇女参与发展的存款保险计划给你块遐deseased休息角落小便大道直上敲打时钟设置,直到午夜解散batttle外地回来了侧面大帽去皮这些轨道是待在马金马金纸堆上升这些ü税这些福斯古惑仔妇女参与发展的一个倾斜伏见亚洲克伯里公墓bettah您卡库斯在知道哟地方拉撤路下来浸泡轩尼诗了403起,给予亚hataz味道给我的脸庞,还是遐一生将是一个废物。。。
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In the four section,we give a kind of method of construction method,we still give an alogrithm for computing Lagrange interpolation polynomial on sphere.and wo give a piecewise interpolation polynomial on sphere and its error estimate.
最后,给出了一种球面分片插值和它的误差估计。
- 推荐网络例句
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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.
另一方面,更重要的是由于城市住房是一种异质性产品。
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Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.
气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。
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You rap, you know we are not so good at rapping, huh?
你唱吧,你也知道我们并不那么擅长说唱,对吧?