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In addition, germ-line epimutations of other tumor suppressor genes, such as MSH2 and BRCA1, have also been reported, demonstrating that epimutations might arise in the germ-line (during gametogenesis or early embryonic development).

随后,关于其他抑癌基因MSH2与BRCA1等的胚系异常甲基化也陆续有报道。这提示,表观突变也可以起源于胚系(生殖细胞形成期或胚胎发育早期),从而造成全身细胞广泛的基因转录沉默。

Easily store food broken bits inside the gums ditch, adhere to a germ spot, become the good district that the germ growth breeds, because it presents to close appearance, don't easily sweep and often cause the gum burning disease and tooth the paroxysm occurrence is for week.

龈沟内易积存食物碎屑,附着菌斑,成为细菌生长繁殖的良好区域,由于其呈封闭状态,不易清洁,常导致牙龈炎症及牙周疾病的发生。

Because of the characteristics of tiny ecoenvironment under the gums, gums next stir up an in great quantities poisonous dint's bigger tooth week to the germ in the germ spot, like gum rod bacteria, in the center type rod bacteria, helicoid etc., make the burning disease of gum aggravated and expand to postpone, cause tooth for week bag formation and the tooth slot bone absorption, make tooth burning for week.

由于龈下微生态环境的特点,龈下菌斑中滋生着大量毒力较大的牙周致病菌,如牙龈类杆菌,中间类杆菌,螺旋体等,使牙龈的炎症加重并扩延,导致牙周袋形成和牙槽骨吸收,造成牙周炎。

This disease much because of the germ spot, tartar, the food Qian fills and badly repairs a body and bites wound etc. to cause, the gum inflammation swells and makes the germ spot piled up to aggravate in the meantime, and is expanded to postpone to the gums bottom by the gums.

本病多因为菌斑,牙石,食物嵌塞,不良修复体,咬创伤等引起,牙龈发炎肿胀,同时使菌斑堆积加重,并由龈上向龈下扩延。

The tartar is a gums various tooth week the harmful germ stirs up a ratio can not little"carry a body", because the gum atrophies, but be disgusted with making oxygen germ can stir up, spread under the gums, hit gum and tooth over a long period of time the week organizes of health;In the meantime such as front say of because of the malnutrition of gum, this eliminates that long under, then cause the adult mouth cavity resist the disease violate of ability, along with age growth but significantly decadent result, thus cause various gum burning, tooth week burning, tooth Sui burning symptom.

牙石是龈下各种牙周有害病菌滋生比不可少的"载体",由于牙龈萎缩,而令厌氧菌在龈下得以滋生、扩散,长期侵袭着牙龈和牙周组织的健康;同时如前面所说的由于牙龈的营养不良,此消彼长之下,进而导致成年人口腔抵抗疾病侵害的能力,随着年龄增长而大幅衰退的结果,从而引发各种牙龈炎、牙周炎、牙髓炎症状。

The results are as follows:Defatted wheat germ was micronized useing both hammer mill and colloid mill to increase the extraction rate of protein, followed by alkali extraction and ultrafiltration, respectively. A quadratic mathematical model was statistically constructed by using of Box-Behnken central composite design and response surface methodology. Under the optimized processing parameters of 23μm particle sizes, pH 9.5 and 51℃, a maximum extraction rate, 68.6%, was achieved, which is 30.63% higher than that of non- micronized wheat germ (passing through 80 mesh sieve).

首先采用锤式粉碎与胶体粉碎相结合的方法对脱脂麦胚进行微细化处理,然后利用碱提、超滤浓缩法提取制备麦胚蛋白,并通过Box-Behnken中心组合设计及响应面分析建立预测麦胚蛋白提取率的二次多项数学模型,优化蛋白质的提取工艺,在麦胚粒度为23μm、pH值9.5、提取温度51℃的条件下,经微细化处理的蛋白提取率为68.6%,比未经微细化处理的(过80目筛)提高30.63%。2。

BA and GA3 in proper concentrations were the effective hormones to induce the germination of germ tube and the germinating rate was 3.3%. When treated with 6-BA + GA3 + IBA, the germinating rate doubled compared with single hormone treatments. However, the germ tube didn't form haustorium afterwards.

结果如下: 1、适当浓度的6-BA和GA3能够诱导肉苁蓉种子萌发形成芽管,芽管萌发率仅为3.3%,6-BA + GA3 + IBA组合使种子芽管萌发率提高2倍,激素只能诱导肉苁蓉种子萌发芽管,不能进一步诱导肉苁蓉种子形成吸器。

They called it "infection of the germ", a neat instance of a modern sounding phrase with an obsolete meaning: the fetus permanently affecting the mother's reserve eggs. this idea was given its impressive greek name, telegony ("at a distance"and "offspring") by august weismann (1834–1914), the german biologist whose rigorous separation of somatic and germinal cells cast doubt on the inheritance of acquired characteristics. weismann believed his notion of the germ plasm could explain telegony, should it be shown to exist, but he doubted its reality.

他们称之为"细菌感染",意思是"胎儿永久影响母亲的储备卵子"。august weismann(1834年~1914年,德国生物学家)给这一理论起了一个令人印象深刻的希腊名字, telegony ("距离"和"后代"),他仔细的分离肉体和生发细胞,对特征遗传提出质疑。weismann相信他的关于遗传物质的概念可以解释telegony,它可能是真的,但weismann怀疑其真实性。

We reviewed the update on germ-line epimutations of TSGs including the possible mechanisms underlying germ-line epimutations, the possibility of transgenerational inheritance, and their impact on our understanding of human disease.

本文着重对近年来抑癌基因胚系表观突变研究进展作一综述,探讨胚系表观突变可能的产生机制和代间遗传的可能性,并展望其给人类疾病病因研究所带来的深远影响。

And we summarized stable treatments of wheat germ and the exploitation of wheat germ products.

叙述了小麦胚的营养价值和功能性成分,对小麦胚稳定化技术进行了综述,同时综述了小麦胚的产品开发,并展望了其广阔的发展前景。

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