查询词典 gene

Recent study showed that the devitalization of DPC4 gene was present in nearly 50% of pancreatic carcinoma, which interrupted the TGF-βsignal pathway, so inactivation of DPC4 gene maybe one of the most important cause of pancreatic carcinoma. The present study was carried out to clarify the effect of DPC4 gene on human pareatic carcinoma cell line JF305, which can help us understand the growth and proliferation mechanism of pancreatic carcinoma and provide us the practical guidance on gene therapy of pancreatic carcinoma.

最新研究资料表明近一半的胰腺癌存在DPC4(deleted in pancreatic carcinoma)失活，进而使TGF-β信号传导途径中断，失去其对肿瘤细胞的抑制作用，导致细胞过度生长和增殖，因此DPC4的改变可能是胰腺癌发生、发展的重要原因之一[2]。

We can make use of chip to analysis virus gene group; construct mutation detection technique of heredity diseases and become normal detection technique of many heredity diseases; supervise the changes of cell gene expression, research pathogenic theory of virus; differentiate bacteria gene types and identify bacteria strains, provide base data for screening and supervise drug-fast gene.

利用基因芯片可加速对病毒基因组的功能分析；可建立遗传病的突变检测技术，并成为对多种遗传病的常规诊断技术；可用来监测宿主细胞基因表达的改变，研究病毒的致病机理；基因芯片还可用来对细菌基因的分型和菌种鉴定，为筛选和监测细菌的抗药性基因提供基础数据。

We can make use of chip to analysis virus gene group; construct mutation detection technique of heredity diseases and become normal detection technique of many heredity diseases; supervise the changes of cell gene expression,research pathogenic theory of virus; differentiate bacteria gene types and identify bacteria strains,provide base data for screening and supervise drug-fast gene.

目前我国在出入境检验检疫中，已开始在基因芯片技术检测传染病病原方面开展了研究工作，国家质检总局动植物检疫所研制出了检测SARS病毒的全基因芯片，极大的促进了出入境检验检疫检测技术的发展，但目前国内外尚未见到有关新城疫病毒基因芯片的报道。

Calcium chloride modified nanoparticles prepared by means of chemistry. Analyse the combination of calcium phosphate nanoparticles and DNA, the protection to DNA as well by gelose gelatin electrophoresis. When the green fluorescence protein gene was regarded as report gene, gene vector of calcium phosphate nanoparticles transfected CNE-2 cell in vitro and vivo. Combine the calcium phosphate nanopartides and suicide gene yCDg1yTK for Nasopharyngeal Carcinoma therapy in vitro.

化学方法制备，氯化钙修饰纳米颗粒，用琼脂糖凝胶电泳分析磷酸钙纳米颗粒与DNA的结合效率及对DNA的保护作用，用绿色荧光蛋白基因作报告基因，将磷酸钙纳米颗粒为基因载体转染鼻咽癌(CNE-2)细胞和在动物体内转染肿瘤细胞；以及将磷酸钙纳米与自杀基因yCDglyTK结合，并在体外对鼻咽癌进行基因治疗。

The ORF2 gene is the most important protein-code gene for porcine circovirus, and is the main gene differing porcine circovirus typel from porcine circovirus type2 (PCV2). To construct a specific PCR detecting method, we designed a pair of primers to amplify a partial fragment of ORF2 gene from PCV2, referring to fifteen strains complete genome published in Genbank. The PCR product was about 0.67kb in size detected by gelose gel electrophoresis.

猪圆环病毒的开放阅读框2(ORF2)是其主要结构蛋白的编码基因，也是区分猪圆环病毒1型(PCV1)和猪圆环病毒2型(PCV2)的重要基因，本研究参照GenBank已发表的15株PCV2基因序列，设计合成一对引物，对PCV2的ORF2基因进行PCR扩增，产物经琼脂糖凝胶电泳，呈现一条大小约0.67kb的特异条带，经条件筛选，建立了猪病料中PCV2感染的PCR检测方法。

It has been widely used in analysis of gene expression map, analysis, discovey of new gene ,gene mutation and polymorphism analysis, genom library map, gene sequence, disease diagnosis and prevention, drug selection, tumor biology and environmental toxicology.

基因芯片技术目前已广泛应用于基因表达谱分析、新基因发现、基因突变及多态性分析、基因组文库作图、基因测序、疾病诊断和预防、药物筛选、药物开发和研究、肿瘤生物学、环境毒理学等研究领域。

We discovered the sequence of cs-acs1g gene from GenBank and designed two pairs of primers according to this gene. Two gene partials were cloned from gynoecium of cucumber (C0208). The relationship between cs-acs1g gene and gynoecium was validated through a combination of PCR method and investigations.

从GenBank中查找到cs-acs1g基因序列，根据该序列设计两对引物，然后从黄瓜(C0208)雌性系材料中克隆2个基因片段，利用PCR扩增方法及田间调查手段相结合，验证cs-acs1g基因的2个片段和雌性系之间的相互关系。

Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关，其机制可能是[3]：直接干扰特异的转录子和各自启动子识别位点的结合；通过改变染色质结构，介导转录抑制；甲基化DNA位点直接与转录抑制子结合，诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ，MTS1) [4] ，是肺癌中最易发生甲基化的抑癌基因，该基因位于人类染色体9p21上，全长8.5kb ，由两个内含子和三个外显子组成。

Microparticle can carry antisense MCP-1 gene into aorta successfully, which can inhibitate MCP-1 gene expression, microphage infusion and slow down the development of AAA. At the same time, there is no MCP-1 gene expression in other position, suggesting the microparticle si an secure gene transfer carrier.

以微粒子为载体，能成功地将反义MCP-1基因导入动脉组织中，并能明显抑制内源性MCP-1基因的表达和巨噬细胞在动脉壁的浸润程度，减缓腹主动脉瘤的进一步生长，同时外源基因在机体的其他部位没有表达，提示微粒子是一种安全的基因转移载体。

Coil O85 antigen contained 8 varieties of genes, including UDP-Nacetylglucosamine-2-epimerase gene (f1). UDP-galactopyranose mutase gene, glycosyl transferase genes (f3, f5, f6, f8), O-antigen transferase gene and O-antigen polymerase gene, in which two genes, wzx and wzy and 4 pairs of primers were identified to be specific to E.

发现8个开放阅读框架并确定功能，分别为：UDP-N-乙酰葡萄糖－2-异构酶基因，吡喃型UDP-半乳糖变位酶基因，糖基转移酶基因（orf3、orf5、orf6和orf8），O-抗原转运酶基因和O-抗原聚合酶基因。

The shaping method of noncircular part and the tool holder's radial motion characters in noncircular turning process are discussed in detail in the thesis.

论文详细研究了非圆零件的成型方法和加工过程中刀架的径向运动规律。

I have not really liked him,I do not like his this kind of disposition.

我没有真的喜欢他，我不喜欢他的这种性格。