查询词典 gelsemium

Objective To identify the structure of the alkaloid extract of Gelsemium from east Guangdong province of China.

目的研究粤东产钩吻生物总碱提取物的结构。

Methods Fourier transform infrared absorption spectrometry, hydrogen and carbon spectra of nuclear magnetic resonance and distortionless enhancement by polarization transfer analysis were used for the structural identification of the alkaloid exstract of Gelsemium.

方法采用傅里叶变换红外光谱、核磁共振氢谱(1HNMR)与碳谱(13CNMR)、无畸变极化转移增益(distortionlessenhancementbypolarizationtransfer，DEPT)波谱分析及元素分析阐明该提取物的化学结构。

Aim To study chemical constituents of Gelsemium elegans Benth.

目的 对胡蔓藤中的化学成分进行研究。

People were sorry to hear his death, they call the plant as "Gelsemium elegans".

人们非常难过，把这种草称为"断肠草"。

The alkaloid contents of Chinese gelsemium G.

重研究了国产钩吻生物碱，比较和改良这些生物碱的提取方法。

In these studies, gelsemium were obtained from suburb YuLin city, Guangxi province .The gelsemium total alkaloids which were the main toxicity constituents of the plant were extracted, isolated , identified .Acute toxic and subchronic tests on mice were further studied. The experiment established foundation of production and application of poisonous plant Gou-Wen.

本试验以广西玉林市郊外的钩吻植株为材料，提取、分离、鉴定其主要毒性成分钩吻生物碱，并进一步研究了钩吻生物碱对小鼠的急性毒性和亚慢性毒性作用，为有毒植物钩吻的生产应用提供了理论依据。

Gelsemium total alkaloids improved some blood and immune function of mice when it less than 0.30mg/kg body weight, but more than 1.5mg/kg body weight, the gelsemium total alkaloids can reduced some blood and immune function of mice; below the dose of 3%, GEB"s power can improve some blood and immune function of broilers, but GEB"s power can reduce some blood and immune function of broilers above the dose of 6%.

结论是：钩吻对小鼠和肉鸡的血液学及免疫功能的影响均存在着剂量差别，钩吻总碱稀释液在0.30mg／kg剂量以下，能够提高小鼠的某些血液指标与免疫功能(p＜0.05)，而在1.5mg／kg以上，则降低小鼠的某些血液指标与免疫功能(p＜0.05)；3％以下的钩吻干粉能够提高肉鸡的某些血液指标与免疫功能，而6％以上的钩吻干粉则降低某些血液指标与免疫功能。

The results showed as follows: 1 Extraction of gelsemium total alkaloids. Total alkaloids were extracted with 95 per cent ethanol. The extract rate was 0.519 per cent and the extract purity were 88.02 per cent and 87.38 per cent; Total alkaloids were extracted with chloroform .The extract rate was 0.416 per cent and the extract purity were 89.02 per cent and 94.52 per cent. 2 Isolation of gelsemium total alkaloids with TLC. Total alkaloids contained five or more alkaloids. The optimal developing agent was chloroform :methanol :ethyl acetate(9:l:0.3),the optimal eluent was methylene chloride:methanol(92:8). 3 Isolation of total alkaloids with column chromatography. Alkaloid A and alkaloid B were obtained, alkaloid B was identified as koumine.

研究结果如下：1、钩吻总碱的提取：用95％的乙醇提取钩吻生物碱提取率为0.519％，其提取物纯度为88.02％、87.35％；用氯仿提取钩吻生物碱提取率为0.416％，其提取物纯度为89.02％、94.52％。2、钩吻总碱的薄层层析分离：总碱中含有5种或5种已上的生物碱；氯仿：甲醇：乙酸乙酯(9：1：0.3)是最佳薄层层析的展开剂；二氯甲烷：甲醇(92：8)是柱层析的最佳洗脱剂。3、钩吻总碱的柱层析分离：共得到两种钩吻生物碱单体成分碱A和碱B，碱B为钩吻素子，碱A可能是钩吻素甲。4、钩吻总碱的急性毒性试验：钩吻总碱小鼠腹腔注射的半数致死量LD_(50是：7.38mg／kg，95％的可信限范围为：6.67mg／kg～7.94mg／kg。

We demonstrated the effect of the gelsemium total alkaloids of on blood and immune function of three different doses (0.15mg/kg,0.30mg/kg,1.5mg/kg) on mice and dieted with three GEB powers contents(1.5%,3%,6%) on chicken . The results showed as follow:1.The gelsemium total alkaloids of 0.15mg/kg,0.30mg/kg doses increased RBQHB, percentage of ANAE+ lymphocytes, phagocyty of peritoneal macrophage of mice.

本研究探讨了不同剂量(0.15mg／kg、0.30mg／kg、1.5mg／kg)的钩吻总碱稀释液对小鼠的血液学与免疫功能的影响，以及不同日粮添加水平(1.5％、3％、6％)的钩吻干粉对肉鸡血液学与免疫功能的影响，结果表明： 1、灌胃0.15mg／kg、0.30mg／kg剂量的钩吻液，能够提高小鼠红细胞数、血红蛋白含量、外周血ANAE~+淋巴细胞数、腹腔巨噬细胞吞噬指数及吞噬百分率。

Alkaloid A might be gelsemine. 4 Actue toxic test of total gelsemium on mice. Its intraperitoneal LDsotmedian lethel value of total gelsemium was 7.38mg/kg(the confident limit on 95 per cent level was 6.67mg/kg ~ 7.94mg/kg).Main clinical symptoms of acute toxified mice were reducing activities, crouching, depression on low dosage (5mg/kg).

小鼠急性中毒的主要临床症状是：在低剂量(〈5mg／kg)作用下呈现活动减少、静伏、精神沉郁；在中高剂量(〉5mg╱kg)作用下呈现为呼吸困难、惊厥、阵发性痉挛甚至死亡。5、钩吻总碱的亚慢性毒性试验：生理盐水对照组和各钩吻总碱处理组1／50LD_

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。