查询词典 gaucher

SAN DIEGO – Untreated patients with type 1 Gaucher disease face a high risk of avascular necrosis during their lifetime, and the risk is greatly increased in untreated splenectomized patients.

圣地亚哥——未经治疗的1型戈谢病患者一生中罹患非血管性坏死的风险增加，在未经治疗的脾切除患者中风险尤其高。

Mistry, professor of pediatrics and internal medicine at Yale University, New Haven, Connecticut, set out to determine the incidence of avascular necrosis in untreated patients with type 1 Gaucher disease, which is the most common disease type.

Mistry博士为领导的研究者开展了这项研究，旨在确定在未经治疗的1型戈谢病患者中非血管性坏死的发生率，1型戈谢病是该病的最常见类型。

However, because the type 1 Gaucher disease population is genotypically and phenotypically heterogeneous, further analyses will attempt to identify characteristics that distinguish untreated patients at high risk of developing avascular necrosis from those who are less likely to develop this serious complication.

但鉴于1型戈谢病患者人群的基因型和表型都存在异质性，因此还需进一步开展分析，以发现能够区分未经治疗的非血管性坏死高风险患者与不大可能出现这一严重并发症的患者的疾病特征。

"We appreciate the guidance and vote of confidence provided by the FDA in establishing a treatment protocol for prGCD and are working closely with physicians and patient advocacy groups to allow Gaucher disease patients to gain access to our drug," commented Dr. David Aviezer, the Company's President and Chief Executive Officer.

"我们赞赏的指导和信任投票林业局提供的建立一个治疗议定书prGCD和密切合作的医生和病人宣传团体，使高雪氏症患者获得我们的药物，"大卫Aviezer博士的公司总裁兼首席执行官。

The former genes cause neurological diseases, such as Tay-Sachs, Gaucher's and Niemann-Pick. The latter cause cancer.

前者会引发神经性疾病，如泰萨二氏病、脑苷脂沉积病和神经鞘磷脂沉积病；而后者会导致癌症。

Glucocerebrosidase, the enzyme defective in Gaucher disease, is targeted to the lysosome independently of the mannose-6-phosphate receptor.

葡糖脑苷脂酶在高雪病患者中表现为缺陷型，它靶向性结合不依赖于甘露糖-6-磷酸的溶酶体。

The myeloproliferation degree in CML is more serious than CLL, there were cellular morphological changes in two types of leukemia, Gaucher cells were seen in CML.

骨髓增生度CML高于CLL，两类白血病细胞形态上有不同程度的改变，CML可见戈谢氏样细胞。

An Israeli clinic devoted to treating people with Gaucher's has vastly more engineers, scientists, accountants and lawyers on its books than would be expected by chance.

根据一家专门治疗脑苷脂沉积病的以色列诊所的医疗记录，患者中的工程师、科学家、会计和律师的比例多于常人。

Discussion: Bone infarcts can be seen in many diseases including sickle cell disease, post-trauma, Gaucher's disease as well as in steroid use.

骨梗死在多种疾病中可见，比如：镰刀细胞白血病、外伤后疾病、戈谢病及类固醇药物使用后。

Metabolic cherry-red spot occurs in other lysosomal enzyme deficiences such as generalized gangliosidosis (GM 1), Sandhoff's, Gaucher's, mucolipidosis Types 1 and 2, Niemann-Pick Type A, and multiple sulfatase deficiency. Vision is usually subnormal because the ganglion cells are not working properly.

代谢性眼部樱桃红斑发生在许多溶酶体酶缺乏的疾病中出现，如GM1神经节苷脂贮积病，sandhoff病，高雪氏病，粘脂质贮积病1，2型，尼曼匹克病A型，及多种硫酸酯酶缺乏病等，由于神经节细胞异常，视力一般轻度受损。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失