查询词典 fungal

New antifungal agents have been developed over the past years based on the discovery of many new target sites of Candida albicands. For example, Echinocandins, aiming at the cell wall of Candida albicands, showed strong antifungal activities to fluconazole resistant candidas and fungal biofilm. Moreover, because β-glucan synthase does not exist on the cell membrane of mammalian cells, Echinocandins has a low toxicity and a promising clinical future. Though the mechanism of Histatin is not clear, it has strong activity not only on candida resistant of polyene and azole, but also to Candida parapsilosis, Candida krusei and Cry ptococcus neoformans. Berberine and Ocimum gratissimum L. were also found to have prominent anti-fungi activities.

近年来相继提出了许多抗白念珠菌药物作用的新靶点并成功开发出一些活性强大，疗效确切的抗真菌药，如以真菌细胞壁为靶点开发出棘白菌素类药物卡泊芬净、米卡芬净等，该类药物主要抑制β-葡聚糖合成酶，体外对氟康唑耐药的念珠菌属及真菌生物被膜表现出强大的抗菌活性，又由于β-葡聚糖合成酶在哺乳类动物细胞内不存在，故具有高效低毒的临床效果，是一极具前途的新型抗真菌药；以真菌细胞膜为靶点开发出Histatin类药物，虽然作用机制目前还不完全明了，但其作用不同于临床常用的多烯类和氮唑类，并已经发现Histatin5对两性霉素B和氮唑类耐药的念珠菌有效，并且对非白念珠菌如光滑念珠菌、克柔氏念株菌、隐球菌等也有杀灭作用；通过对植物药物的研究发现黄连素和丁香罗勒Ocimum gratissimum L。

Methods Nail samples were collected from patients with suspicious onychopathy, and inoculated into modified DTM, DTM, Sabouraud dextrose agar fortified with cycloheximide and chloromycetin and Sabouraud dextrose agar fortified with chloromycetin respectively. The initial time of fungal growth and of discoloration of medium, as well as the colony diameter at the beginning of discoloration, were documented.

收集临床拟诊甲真菌病的标本，分别接种于改良DTM、DTM、含放线菌酮及氯霉素的沙氏培养基和含氯霉素的沙氏培养基；记录菌株的开始生长时间、培养基开始变色时间及开始变色时菌落的直径。

The experimental dada from Phaseolus vulgaris L. and Triticum aestivum L. indicate that the level of pgip gene transcription and translation is closely related to fungal infection, but this mechanism need further study.

来自菜豆和小麦的实验证据表明病原真菌侵染植株能诱导pgip基因高水平转录、表达，但pgip基因家族对这种诱导信号应答的分子机制待于进一步研究。

Based on phenotypical and biochemical properties as well as its 16S rRNA gene sequence, the bacterium was identified as Paenibacillus polymyxa. In vitro antifungal spectrum assay vindicate that it was active against a broad range of phytopathogens and inhibited the growth of thirteen fungal pathogens.

采用对峙培养法筛选拮抗内生细菌，根据菌株形态、生理生化特性结合16S rRNA基因序列分析鉴定菌株；采用硫酸铵沉淀法提取抗菌粗蛋白，研究其对水稻恶苗病菌菌丝生长和孢子萌发的影响。

Fungal elicitors were extracted from Colletorichum lagnarinm, Phoma filtrate, Fusarium oxysponum, Asperillus niger and culture with HRPG. The total ginseng sponin and four kinds of monomeric sponins were analysed by UV spectrophotometry and RP HPLC.

提取黄瓜炭疽病菌 Colletorichumlagnarinm 、青菜炭疽病菌 Phomafiltrate 、棉花枯萎病菌 Fusariumoxysponum 、黑曲霉 Asperillusniger 中的真菌诱导子与人参毛状根共培养，应用HPLC及比色法对培养物中总苷及几种单体皂苷进行分析测定。

The purpose of this study is to screen microorganisms with growth inhibition against plant fungal pathogens. The plate-dilution method was used to isolate the bacteria from salt marshes at Dafeng, Jiangsu. The antifungal activity of the bacterial broth filtrates against 5 phytopathogens was determined using mycelial disk method. The antifungal compositions of four active bacteria were analyzed primarily with chromatography techniques. Two hundred and thirty-five aerobic (92) and anaerobic (143) bacterial strains have been isolated from the coast salt marsh and sixty-five strains, of which 39 are aerobic and 26 are anaerobic showed greater than 30% of inhibition rate against the growth of at least one of the phytopathogenic fungi on petri dish.

为了开发对植物病原真菌生长有抑制作用的药源微生物，本实验采用平板稀释法从江苏大丰盐沼湿地土壤中分离微生物，并通过菌丝块法检测这些微生物代谢产物对5种植物病原真菌生长的抑制活性，进而利用柱层析分析其活性成分；结果共分离得到235株细菌，其中好氧细菌92株，厌氧细菌143株；体外活性测试结果显示有65株至少对1种测试植物病原真菌的抑制率在30%以上，其中好氧菌39株，厌氧菌26株。

While diagnosing and treating SARS cases, doctors should rule out the possibility of other lung diseases with similar clinical manifestations, such as primary bacterial or fungal pneumonia, pulmonary tuberculosis, lung tumor, non-infective interstitial lung diseases, pneumonedema, atelectasis, pulmonary embolism, pulmonary infiltration with eosinophilia, and pulmonary agents.

答：在非典型肺炎的诊断治疗过程中，首先要注意排除原发细菌性或真菌性肺炎、肺结核、肺部肿瘤、非感染性肺间质性疾病、肺水肿、肺不张、肺栓塞、肺嗜酸性粒细胞浸润症、肺血管炎等临床表现类似的肺部疾患。

The pathologic changes of fungal diseases in alimentary canal were tissue necrosis, ulcer formation and pseudomembranous inflammation.

其病变为消化道组织坏死、溃疡形成及假膜性炎症；炎细胞浸润不明显，且以单核细胞浸润为主；假膜性炎中有较多的中性粒细胞渗出，可能与某些细菌的混合感染有关系。

Puccinia striiformis f. Sp. Tritici is one of the most economically important fungal pathogen of wheat worldwide. However, very little is known about its genome and gene functions, which can be critical for developing the disease management strategies.

小麦条锈菌(Puccinia striiformis f.sp.tritici)是全世界范围内小麦生产上的重要病原真菌，但是对小麦条锈菌的基因组和基因功能却了解甚少。

Abstract］ Objective: To provide a suitable fungal material for protoplast-mediated genetic transformation and mutation induction of Pythium guiyangense Su.

目的：建立贵阳腐霉原生质体的制备和再生系统，为该菌的基因工程和细胞工程改良提供适宜的真菌状态。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失