查询词典 fractional replication

Antitumor efficacy of replication-competent adenovirus CNHK500 in vivo was associated with increased dosage of CNHK500. Conclusions: The results prove that CNHK500 has highly proliferation selectivity and potent cytolysis effect on breast cancer.

肿瘤选择性增殖腺病毒CNHK500可选择性在端粒酶阳性的乳腺癌细胞中复制，并产生体内外杀伤作用。

Because different cell lines may show various levels of susceptibility to adenovirus infection and virus production, non-selectively replicating wtAd5 was used to be a comparison with the tested conditionally replicating adenovirus CNHK500.ONYX-015, the first replication-competent adenovirus entered into clinical trials was also used to be a comparison. We used virus proliferation assay, cell viability assay and western blot to evaluate the proliferation and cytolysis selectivity of CNHK500. Results demonstrated that the CNHK500 virus proliferation multiples in breast cancer cell lines after 48 hours is similar to that of wtAd5, ONYX-015 virus proliferation ability is less than that of CNHK500 in cancer cells.

然后，通过与ONYX-015（E1B 55 KD a蛋白缺失的2型和5型嵌和型腺病毒，美国ONYX生化制药公司研制）、wtAd5进行对比，利用病毒增殖实验和细胞生长抑制实验，验证了CNHK500选择性增殖能力和肿瘤特异性杀伤作用；利用Western Blot检测CNHK500腺病毒E1A和E1B在乳腺癌细胞和正常成纤维细胞中的表达差异，揭示了腺病毒肿瘤靶向性的机制；利用携带绿色荧光蛋白的CNHK500-EGFP感染乳腺癌细胞株和正常成纤维细胞株，直观地观察其感染乳腺癌细胞的能力和在乳腺癌细胞中的增殖过程。

In addition to humans than chimpanzees are the only primates infected with HIV, but HIV-maneuvers in the human body to body like a chimpanzee was Danian of the same low level of replication does not cause any symptoms of HIV.

黑猩猩是除人类之外唯一能感染HIV的灵长类动物，但在人体内纵横捭阖的HIV到了黑猩猩体内却像被打蔫了一样，复制水平很低，不会引起任何艾滋病症状。

Contribution of asymmetric cytosine deamination was found to be weak to TAP in most phyla, and strong to RAP in all the Proteobacteria but weak in most of the Firmicutes. This possibly reflects the differences in their chromosomal replication machineries.

不对称的cytosine deamination作用对大多数的门中的TAP贡献很小，对Proteobacteria的RAP贡献显著，而对大多数Firmicutes的RAP贡献很小，这可能反映了这两门物种间染色体复制机制的不同。

These skew reflect mainly those in protein coding sequences, which are driven by asymmetric mutation pressures during replication and transcription (notably asymmetric cytosine deamination) plus subsequent selection for preferred structures, signals, amino acid or codons.

这些不对称性主要反应在蛋白质编码序列上，并且主要是受到复制与转录期间复制双股之间的不对称突变压力加上之后为了偏好的结构、信号、胺基酸或转录子的筛选所驱使。

Uracil also can be introduced by hydrolytic deamination of cytosine which paired with guanine. Highly mutagenic dU:dG mispair may cause a C→T transition mutation upon replication if it was not repaired.

另一种可能则是由胞嘧啶(Cytosine； C)发生自发性或氧化脱胺反应而形成尿嘧啶与鸟粪嘌呤的配对错误。

Right now, it co-exists with disk in a tiered storage environment with virtual tape libraries with data deduplication and replication.

现在磁带储存媒体与搭配资料重复删除技术及资料备援功能的虚拟磁带柜产品整合的很好。

The synchronization requirement and the synchronization policy of TMR active replication fault-tolerance system are emphasized with the assumption that the delitescence of error of process\'s kernel data is ignored, so that non-deterministic troubles can be thoroughly eliminated.

其次，按同步定理要求，重点对TMR主动任务复制容错系统的同步必要条件进行研究，通过排除主动复制任务进程的局部非确定性操作对系统同步机制的影响，使系统同步必要条件得到满足，从而设计实现TMR主动任务复制容错系统的同步策略和同步算法。

HBeAg is also detectable in acute infection which is characterized by a high rate of viral replication.

e抗原也是探测急性感染的特点是高利率的病毒复制。

Further studies also show that Dicer can inhibit the replication of the HCV subgenomic replicon.

进一步的研究显示Dicer能抑制HCV的亚基因复制子的复制。

According to our present broadcasting situation,the thesis proposes using new technology to update and reform the present HFC. It also suggests broadcasting using self-advantage and arranging EPON in order to win the supermarket.

论文从我国广电的现状出发，结合实际，积极倡导采用新技术更新、改造我国现有的HFC网络；倡导广电现阶段利用自身优势，部署EPON网络来赢取市场。

A new general kinetic equation was derived in which the effect of the removal of condensation water was taken into account completely, and was applied to the polyesterification kinetic study of AA/HPHP and AA/NPG. It was found that the reaction order of self-catalyzed polyesterification was not constant. For these polyesterifications, the reaction order was 2.5 at a low temperature, while 3.0 at a high temperature.

考虑缩合水的排除对反应体系的影响，用体积浓度单位推导出一个新的聚酯反应总包动力学方程，并应用到AA/HPHP和AA/NPG两个聚酯化反应的动力学研究中，研究发现，自催化聚酯反应的反应级数并不是固定值，对于AA/HPHP和AA/NPG两个聚酯化反应而言，低温时反应级数为2.5，高温时反应级数为3.0。