查询词典 found upon

After the exposure, the retinas were examined with light and electron microscope. results: under light microscope, irregular nucleoplasm and unclear border of nucleus in the ganglion cell layer were found in the experimental groups of 2 h, 12 h and 24 h. these changes were also found in the inner nucleus layer. under the electron microscope, swollen mitochondria and vacuolized endoplasmic reticulums were found in all the layers of retina in the groups of 2 h, 12 h and 24 h, most obvious in the group of 24 h. in the group of 72 h, only lightly swollen mitochondria and dilated endoplasmic reticulums were found in the ganglion cell layer of retina.

结果： 光镜：实验组中2，12及24 h组均可见视网膜神经节细胞层内细胞核出现核质不均匀，核边界不清，内核层细胞核也有同样改变；电镜：实验组中2，12及24 h组视网膜各层均出现线粒体肿大，内质网空泡样变，以24 h组最为严重，72 h组仅见视网膜神经节细胞层出现轻度线粒体肿大，内质网扩张。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法，研究丘脑网状核(nucleus reticularis thalami，RT)中γ-氨基丁酸(gamma-amino butyric acid ，GABA)能神经元、一氧化氮(nitrogen monoxidum，NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate，cAMP)及中缝背核(nucleus raphes dorsalis，DRN)至RT的5-羟色胺(5-hydroxytryptamine，5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP，5μg)，注射当天睡眠时间略有减少，第二日睡眠时间显著减少，觉醒时间明显增多，第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后，与生理盐水组比较，睡眠时间增加，觉醒时间减少；而RT内微量注射L-谷氨酸(glutamic acid， L-Glu， 0.2μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline，BIC，1.0μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen，BAC，1.0μg)后，产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg，0.5μg)后，与生理盐水组对比，睡眠时间略有减少，但无显著性意义；而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside，SNP，0.2μg)后可明显增加觉醒时间，缩短睡眠时间；微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine，L-NNA，2.0μg)后，引起睡眠时间增多，觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用；RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后，与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠，其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate，MOR，1.0μg)后与生理盐水组对比，睡眠时间减少而觉醒时间增加； RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride，NAL，1.0μg)后与生理盐水组比较，睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后，与生理盐水组对比，原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较，睡眠时间增多而觉醒时间减少；RT内微量注射亚甲蓝(methylene blue，MB，1.0μg)后，与NS组比较，睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 0.2μg)比较，睡眠时间减少，觉醒时间增多；大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射二甲基麦角新碱(methysergide， MS， 1.0μg )后，与对照组(DRN注射L-Glu 0.2μg，双侧RT注射NS 1.0μg)比较，睡眠时间增多，觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine，PCPA，10μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 1.0μg)比较，睡眠时间增多，觉醒时间减少；大鼠DRN内微量注射PCPA(10μg)，产生睡眠增多效应后，在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan ， 5-HTP， 1.0μg )后，与对照组(DRN注射PCPA 10μg，双侧RT注射NS 1.0μg)比较，睡眠时间减少，觉醒时间增多。

Sapphire from Shandon and Hainan commonly have the reaction border, we found out this reaction border enriched with Fe,Mg,and K by testing its components; We also studied the inclusion in the sapphire, and found many KC1 crystal grain with variety of size, a melt inclusion enriched with K,Si, is also found, this may suggest an assimilationary-magmatic course; Besides that, another minerl inclusions such as enstenite, magnetite, chromite, zircon are also found.

观察到了山东、海南蓝宝石普遍存在的反应边，并测试了反应边的成分，证实其以富Fe，Mg，和K为特征；研究了蓝宝石里面的包体，发现蓝宝石里面存在着大小不等的KCl的结晶颗粒，还发现了富K富Si的熔浆包裹体，说明其形成过程中有同化混染的贡献；此外还发现了斜方辉石，磁铁矿，铬铁矿，锆石的包体矿物。

Upon this, I told him the first Thing we had to do, was to stave the Boat, which lay upon the Beach, so that they might not carry her off; and taking every Thing out of her, leave her so far useless as not to be fit to swim; accordingly we went on board, took the Arms which were left on board, out of her, and whatever else we found there, which was a Bottle of Brandy, and another of Rum, a few Bisket Cakes, a Horn of Powder, and a great Lump of Sugar, in a Piece of Canvas; the Sugar was five or six Pounds; all which was very welcome to me, especially the Brandy, and Sugar, of which I had had none left for many Years.

于是，我告诉他，我们首先应该把搁浅在沙滩上的那只小船凿破，把船上所有的东西都拿下来，使它无法下水，他们就无法把它划走。于是我们一起上了小船，把留在上面的那支枪拿了下来，又把上面所能找到的东西通通拿下来。其中有一瓶白兰地，一瓶甘蔗酒，几块饼干，一角火药，以及一大包用帆布包着的糖，大约有五六磅重。这些东西我都非常需要，尤其是糖和白兰地，我已吃光好多年了。

One morning early, lying in my bed, andfilled with thoughts about my danger from the appearances ofsavages, I found it discomposed me very much; upon which thesewords of the Scripture came into my thoughts,"Call upon Me in theday of trouble, and I will deliver thee, and thou shalt glorifyMe."

感谢上帝，上帝的圣灵用上帝的语言教导我们，引导我们认识真理，使我们心悦诚服地服从上帝的指示。所以，即使我们十分了解造成世界上巨大混乱的那些宗教上的争执，在我看来对我们也毫无用处。现在，我还是把一些重要的事情，按发生的先后顺序，继续讲下去吧。

We had found from previous experience that none of our Legation people or servants could be depended upon to do anything when traveling, in consequence of which the entire charge devolved upon my mother, who was without doubt the genius of the party in arranging matters and straightening out difficulties.

从以前的经验来看，在旅途中发生事情的话没有任何一个公使馆的人和仆人可以依靠，所以所有的事情都要母亲来处理。母亲的确是处理麻烦事情和解决难题的天才。

All this Labour I was at the Expence of, purely from my Apprehensions on the Account of the Print of a Man's Foot which I had seen; for as yet I never saw any human Creature come near the Island, and I had now liv'd two Years under these Uneasinesses, which indeed made my Life much less comfortable than it was before; as may well be imagin'd by any who know what it is to live in the constant Snare of the Fear of Man; and this I must observe with Grief too, that the Discomposure of my Mind had too great Impressions also upon the religious Part of my Thoughts, for the Dread and Terror of falling into the Hands of Savages and Canibals, lay so upon my Spirits, that I seldom found my self in a due Temper for Application to my Maker, at least not with the sedate Calmness and Resignation of Soul which I was wont to do; I rather pray'd to God as under great Affliction and Pressure of Mind, surrounded with Danger, and in Expectation every Night of being murther'd and devour'd before Morning; and I must testify from my Experience, that a Temper of Peace, Thankfulness, Love and Affection, is much more the proper Frame for Prayer than that of Terror and Discomposure; and that under the Dread of Mischief impending, a Man is no more fit for a comforting Performance of the Duty of praying to God, than he is for Repentance on a sick Bed: For these Discomposures affect the Mind as the others do the Body; and the Discomposure of the Mind must necessarily be as great a Disability as that of the Body, and much greater, Praying to God being properly an Act Of the Mind, not of the Body.

现在，再接着说说我接下去做的事。我把一部分家畜安置妥当后，便走遍全岛，想再找一片这样深幽的地方，建立一个同样的小圈地养羊。我一直往岛的西部走，到了一个我从前从未涉足的地方。我往海里一看，仿佛看到极远处有一只船。我曾从破船上一个水手的箱子里找到了一两只望远镜，可惜没有带在身边。那船影太远，我也说不准到底是否是船。

We hung about the stadium, we've got no place to stay We hung about the tenderloin and tenderly you tell About the saddest book you ever read that always makes you cry The statue's crying too and well he may I love you I've a drowning grip on your adoring face I love you my responsibility has found a place Beside you and strong warnings in the guise of gentle words Come wave upon me from the family wider net absurd "You'll take care of her, I know it, you will do a better job" Maybe, but not what she deserves Elope with me Miss Private and we'll drink ourselves awake We'll taste the coffee houses and award certificates A privy seal to keep the feel of 1960 style We'll comment on the decor and we'll help the passer by And at dusk when work is over we'll continue the debate In a borrowed bedroom virginal and spare The catcher hits for .318 and catches every day The pitcher puts religion first and rests on holidays He goes into cathedrals and lies prostrate on the floor He knows the drink affects his speed he's praying for a doorway Back into the life he wants and the confession of the bench Life outside the diamond is a wrench I wish that you were here with me to pass the dull weekend I know it wouldn't come to love, my heroine pretend A lady stepping from the songs we love until this day You'd settle for an epitaph like "Walk Away, Renee" The sun upon the roof in winter will draw you out like a flower Meet you at the statue in an hour Meet you at the statue in an hour

我们红约大球场，我们已经准备好没有住宿地点我们红关于tenderloin和温柔，你告诉关于最悲惨的书，你读总是让你哭雕像的哭声太以及他可能我爱你我已经一溺水掌握在您的崇拜面对我爱你，我有责任找到一个地方旁边的你和强烈的警告，假借温柔的话来波后，把我从更广泛的家庭净荒谬"你可以照顾她，我知道它，你会做的更好"也许，但不是什么值得她 elope与我错过私人，我们会喝自己清醒我们将品尝到咖啡的房屋和颁授证书 1枢密院密封，以保持觉得1960年的作风我们会发表评论装潢和我们将帮助途由和黄昏时的工作是超过我们将继续辩论在借来的卧室处女和备件捕手安打为0.318和捕捞的渔获，每一天投手把宗教首先在于对假期他进入大教堂和谎言前列腺在地板上他知道酒后影响他的速度，他的祈祷一大门口回到生活，他希望和认罪的板凳生活以外的钻石是一个扳手我希望你在这里跟我通过平淡的周末我知道它不会来的爱，我的女主人公假装一位加强从我们热爱的歌曲，直到这一天您想要解决为墓志铭一样，"走开，蕾妮"太阳后，屋顶在冬季将以此为你喜欢的花满足你的雕像在一个小时满足你的雕像在一个小时

To milk my She-goats, and manage my little Flock, in the Wood; which as it was quite on the other Part of the Island, was quite out of Danger; for certain it is, that these Savage People who sometimes haunted this Island, never came with any Thoughts of finding any Thing here; and consequently never wandred off from the Coast; and I doubt not, but they might have been several Times on Shore, after my Apprehensions of them had made me cautious as well as before; and indeed, I look'd back with some Horror upon the Thoughts of what my Condition would have been, if I had chop'd upon them, and been discover'd before that, when naked and unarm'd, except with one Gun, and that loaden often only with small Shot, I walk'd every where peeping, and peeping about the Island, to see what I could get; what a Surprise should I have been in, if when I discover'd the Print of a Man's Foot, I had instead of that, seen fifteen or twenty Savages, and found them pursuing me, and by the Swiftness of their Running, no Possibility of my escaping them.

羊群在岛的另一边，因此没有什么危险。因为那些偶尔上岛的野人，从来没有想在岛上找到什么东西，所以他们从不离开海岸向岛里走。我也毫不怀疑，自从我处处小心提防他们之后，他们还照常到岛上来过好几次。真的，我一想到我过去出游的情况，不禁不寒而栗。我以前外出只带一支枪，枪里装的也是一些小子弹。就这样我在岛上到处东走走，西瞧瞧，看看能不能弄到什么吃的东西。在这种情况下，假使碰上他们，或被他们发现，我该怎么办呢？因为，我没有多少自卫能力。或者，假定我当时看到的不是一个人的脚印，而是一二十个野人，一见到我就向我追来。他们善于奔跑，我是无论如何跑不过他们的，那我必定会落在他们手里！

They found that 27 (73%) patients had iron-deficiency anemia, as confirmed by bone marrow aspiration, while two (5.4%) patients had dilutional anemia, as indicated by normal red blood cell olumes on chromium radioisotope-labeled erythrocyte analysis, and one (2.7%) had enalapril-induced anemia that resoled upon treatment discontinuation and returned upon treatment rechallenge.

他们发现27个(73%)患者经骨髓穿刺诊断患有缺铁性贫血，2个(5.4%)患者经铬标记红血球分析红细胞法诊断稀释性贫血，1个(2.7%)因中途停药后又重新治疗的患者患了依那普利引起的贫血。

You can do some assertiveness training.

你可以进行一些自信训练。

We were well on the path to making a rear-wheel-drive global platform," says Mays."

我们正致力于建立一个后轮驱动的平台，"Mays这样说道。"